Studied + deposited research ligandReported probe
BI-9321
NSD3
SPR Kd= 166 ± 3 nMOne source observation · PMID:31285596
3 matching observations1 PWWP research-ligand PDB entries
Scientific evidence classification · Phase 6A preserved + Phase 6B additions
PWWP Compounds
& Bioactivity
Explore experimentally studied preparations separately from deposited research ligands, buffers, ions and unresolved chemical evidence. Every role is source- and target-context specific.
Different denominators · 26 October 2026
38studied preparation profiles · 26 baseline + 12 new
109profiles with PWWP research-ligand geometry
93source assay / association observations · 80 baseline + 13 new
Combined Phase 6A + Phase 6B denominators. These groups overlap; the 109 structurally source-tagged research ligands are unchanged. Deposited components and reagents are not automatically biochemical binders.
Evidence classification · exact source records
109 matching profiles
26 matching assay / association observations. Counts here are profiles, not unique assay events or deposited ligand instances; views overlap.
Identity, assays & sources
Studied + deposited research ligandReported probe
UNC6934
NSD2NSD3
SPR Kd= 91 ± 8 nMOne source observation · PMID:34782742
6 matching observations1 PWWP research-ligand PDB entries
Studied + deposited research ligand
BPP
BRPF1DNMT3BGLYR1HDGFL2HDGFL3+2 targets
NMR chemical-shift perturbation Kd= 7 ± 5 µMOne source observation · PMID:39031937
8 matching observations2 PWWP research-ligand PDB entries
Studied + deposited research ligand
compound 7 (Collie 2025)
NSD2NSD3
SPR Kd= 0.15 ± 0.02 µMOne source observation · PMID:40959233
4 matching observations1 PWWP research-ligand PDB entries
Studied + deposited research ligand
MR837 (3f)
NSD2
SPR Kd= 7 ± 3 µMOne source observation · PMID:33522809
2 matching observations1 PWWP research-ligand PDB entries
Studied + deposited research ligand
MRT866
NSD2
SPR Kd= 349 ± 19 nMOne source observation · PMID:34782742
1 matching observations2 PWWP research-ligand PDB entries
Studied + deposited research ligand
varenicline
HDGFL2
NMR chemical-shift perturbation Kd= 250 ± 40 µMOne source observation · PMID:39031937
2 matching observations1 PWWP research-ligand PDB entries
Source identityDepiction not verified
Source SMILES and full InChIKey require reconciliation.
Deposited research ligand · no curated assay
(1R)-N-methyl-1-(pyridin-4-yl)propan-1-amine
HDGFL2
Source verification is pending.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
(1S)-1-(1-phenyl-1H-1,2,3-triazol-4-yl)ethan-1-amine
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
(2,6-difluorophenyl)(pyrrolidin-1-yl)methanone
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
(2R)-1-(2-methyl-1H-imidazol-1-yl)propan-2-ol
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Source identityDepiction not verified
Source SMILES and full InChIKey require reconciliation.
Deposited research ligand · no curated assay
(2R)-1-(cyclohexylamino)propan-2-ol
HDGFL2
Source verification is pending.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
(2R)-2-ethyl-N,N-dimethylmorpholine-4-sulfonamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
(2R)-2-phenylpropane-1-sulfonamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of (2S)-1-[4-[[(3R)-1,1-bis(oxidanylidene)thiolan-3-yl]methyl-methyl-amino]-6-methyl-pyrimidin-2-yl]-N-methyl-pyrrolidine-2-carboxamide](/compounds/depiction/0a262befb369d4ee0287-light.svg)
![Verified 2D molecular structure of (2S)-1-[4-[[(3R)-1,1-bis(oxidanylidene)thiolan-3-yl]methyl-methyl-amino]-6-methyl-pyrimidin-2-yl]-N-methyl-pyrrolidine-2-carboxamide](/compounds/depiction/0a262befb369d4ee0287-dark.svg)
Deposited research ligand · no curated assay
(2S)-1-[4-[[(3R)-1,1-bis(oxidanylidene)thiolan-3-yl]methyl-methyl-amino]-6-methyl-pyrimidin-2-yl]-N-methyl-pyrrolidine-2-carboxamide
NSD2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of (2S)-1-[4-[[(3S)-1,1-bis(oxidanylidene)thiolan-3-yl]methyl-methyl-amino]-6-methyl-pyrimidin-2-yl]-N-methyl-pyrrolidine-2-carboxamide](/compounds/depiction/baa8ac5817f9f50c15af-light.svg)
![Verified 2D molecular structure of (2S)-1-[4-[[(3S)-1,1-bis(oxidanylidene)thiolan-3-yl]methyl-methyl-amino]-6-methyl-pyrimidin-2-yl]-N-methyl-pyrrolidine-2-carboxamide](/compounds/depiction/baa8ac5817f9f50c15af-dark.svg)
Deposited research ligand · no curated assay
(2S)-1-[4-[[(3S)-1,1-bis(oxidanylidene)thiolan-3-yl]methyl-methyl-amino]-6-methyl-pyrimidin-2-yl]-N-methyl-pyrrolidine-2-carboxamide
NSD2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Source identityDepiction not verified
Source SMILES and full InChIKey require reconciliation.
Deposited research ligand · no curated assay
(2S)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)oxolane-2-carboxamide
HDGFL2
Source verification is pending.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of (2S,5R)-4-[(5-chloro-1,2,3-thiadiazol-4-yl)methyl]-2,5-dimethylmorpholine](/compounds/depiction/560f2aeb5644890698d8-light.svg)
![Verified 2D molecular structure of (2S,5R)-4-[(5-chloro-1,2,3-thiadiazol-4-yl)methyl]-2,5-dimethylmorpholine](/compounds/depiction/560f2aeb5644890698d8-dark.svg)
Deposited research ligand · no curated assay
(2S,5R)-4-[(5-chloro-1,2,3-thiadiazol-4-yl)methyl]-2,5-dimethylmorpholine
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of (2~{S})-1-[2-hydroxyethyl-[(2~{S})-2-oxidanylpropyl]amino]propan-2-ol](/compounds/depiction/5bfc68b5c2a69a39cb07-light.svg)
![Verified 2D molecular structure of (2~{S})-1-[2-hydroxyethyl-[(2~{S})-2-oxidanylpropyl]amino]propan-2-ol](/compounds/depiction/5bfc68b5c2a69a39cb07-dark.svg)
Deposited research ligand · no curated assay
(2~{S})-1-[2-hydroxyethyl-[(2~{S})-2-oxidanylpropyl]amino]propan-2-ol
DNMT3B
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
(2~{S})-6-methyl-~{N}-propan-2-yl-heptan-2-amine
DNMT3B
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Source identityDepiction not verified
Source SMILES and full InChIKey require reconciliation.
Deposited research ligand · no curated assay
(3R)-N-methyl-1-(pyridazin-3-yl)piperidin-3-amine
HDGFL2
Source verification is pending.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
(3S)-1-(methanesulfonyl)piperidine-3-carboxylic acid
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of (4-methylpiperazin-1-yl)[(2R)-oxolan-2-yl]methanone](/compounds/depiction/c3891a6f786e387c734a-light.svg)
![Verified 2D molecular structure of (4-methylpiperazin-1-yl)[(2R)-oxolan-2-yl]methanone](/compounds/depiction/c3891a6f786e387c734a-dark.svg)
Deposited research ligand · no curated assay
(4-methylpiperazin-1-yl)[(2R)-oxolan-2-yl]methanone
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of (5S)-7-(pyrazin-2-yl)-2-oxa-7-azaspiro[4.4]nonane](/compounds/depiction/536652fcd633bca3c1cf-light.svg)
![Verified 2D molecular structure of (5S)-7-(pyrazin-2-yl)-2-oxa-7-azaspiro[4.4]nonane](/compounds/depiction/536652fcd633bca3c1cf-dark.svg)
Deposited research ligand · no curated assay
(5S)-7-(pyrazin-2-yl)-2-oxa-7-azaspiro[4.4]nonane
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of (5~{R})-7-pyrazin-2-yl-2-oxa-7-azaspiro[4.4]nonane](/compounds/depiction/f6cb3b7c6ddfd4f326ea-light.svg)
![Verified 2D molecular structure of (5~{R})-7-pyrazin-2-yl-2-oxa-7-azaspiro[4.4]nonane](/compounds/depiction/f6cb3b7c6ddfd4f326ea-dark.svg)
Deposited research ligand · no curated assay
(5~{R})-7-pyrazin-2-yl-2-oxa-7-azaspiro[4.4]nonane
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
(6R)-6-(3,5-dichlorophenyl)morpholin-3-one
NSD2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
(Z)-N-methyl-3-sulfanyl-prop-2-enamide
NSD2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
1-(1,4-diazepan-1-yl)ethan-1-one
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
1-(2-ethyl-1,3-thiazol-5-yl)-N-methylmethanamine
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 1-(5-{9-[(4-{2-[(2S,3R)-2-(3,5-dichloro-4-fluorophenyl)-5-oxomorpholin-3-yl]ethyl}piperazin-1-yl)methyl]-3-azaspiro[5.5]undecane-3-carbonyl}-2-methylphenyl)-1,3-diazinane-2,4-dione](/compounds/depiction/b73cfe57eabe372da74e-light.svg)
![Verified 2D molecular structure of 1-(5-{9-[(4-{2-[(2S,3R)-2-(3,5-dichloro-4-fluorophenyl)-5-oxomorpholin-3-yl]ethyl}piperazin-1-yl)methyl]-3-azaspiro[5.5]undecane-3-carbonyl}-2-methylphenyl)-1,3-diazinane-2,4-dione](/compounds/depiction/b73cfe57eabe372da74e-dark.svg)
Deposited research ligand · no curated assay
1-(5-{9-[(4-{2-[(2S,3R)-2-(3,5-dichloro-4-fluorophenyl)-5-oxomorpholin-3-yl]ethyl}piperazin-1-yl)methyl]-3-azaspiro[5.5]undecane-3-carbonyl}-2-methylphenyl)-1,3-diazinane-2,4-dione
NSD2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
1-(diphenylmethyl)azetidin-3-ol
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
1-(ethanesulfonyl)piperidine-4-carboxylic acid
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
1-(methanesulfonyl)piperidin-4-ol
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
1-(propan-2-yl)-1H-imidazole-4-sulfonamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 1-[(1-methyl-1H-pyrazol-4-yl)methyl]piperazine](/compounds/depiction/01780619bb072c88b5bc-light.svg)
![Verified 2D molecular structure of 1-[(1-methyl-1H-pyrazol-4-yl)methyl]piperazine](/compounds/depiction/01780619bb072c88b5bc-dark.svg)
Deposited research ligand · no curated assay
1-[(1-methyl-1H-pyrazol-4-yl)methyl]piperazine
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 1-[(thiophen-3-yl)methyl]piperidin-4-ol](/compounds/depiction/a4d4b05caad27905944a-light.svg)
![Verified 2D molecular structure of 1-[(thiophen-3-yl)methyl]piperidin-4-ol](/compounds/depiction/a4d4b05caad27905944a-dark.svg)
Deposited research ligand · no curated assay
1-[(thiophen-3-yl)methyl]piperidin-4-ol
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
1-bromanyl-4-methylsulfonyl-benzene
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
1-cyclohexyl-N-methylmethanesulfonamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
2-(2,2-dimethylpyrrolidin-1-yl)ethan-1-amine
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
2-(4-bromanylpyrazol-1-yl)-~{N}-cyclopropyl-~{N}-methyl-ethanamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
2-(4-fluorophenoxy)-1-(pyrrolidin-1-yl)ethan-1-one
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Source identityDepiction not verified
Source SMILES and full InChIKey require reconciliation.
Deposited research ligand · no curated assay
2-[(2S)-2-methylpiperidin-1-yl]ethan-1-amine
HDGFL2
Source verification is pending.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 2-[(~{E})-2-thiophen-2-ylethenyl]benzoic acid](/compounds/depiction/2ea4c42c778a41e7a970-light.svg)
![Verified 2D molecular structure of 2-[(~{E})-2-thiophen-2-ylethenyl]benzoic acid](/compounds/depiction/2ea4c42c778a41e7a970-dark.svg)
Deposited research ligand · no curated assay
2-[(~{E})-2-thiophen-2-ylethenyl]benzoic acid
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 2-[4-(propan-2-yl)piperazin-1-yl]pyrimidine](/compounds/depiction/43b6bbd13490ba0ef66f-light.svg)
![Verified 2D molecular structure of 2-[4-(propan-2-yl)piperazin-1-yl]pyrimidine](/compounds/depiction/43b6bbd13490ba0ef66f-dark.svg)
Deposited research ligand · no curated assay
2-[4-(propan-2-yl)piperazin-1-yl]pyrimidine
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 2-[methyl(pyridin-2-yl)amino]ethan-1-ol](/compounds/depiction/58d172793d6b7bea9c09-light.svg)
![Verified 2D molecular structure of 2-[methyl(pyridin-2-yl)amino]ethan-1-ol](/compounds/depiction/58d172793d6b7bea9c09-dark.svg)
Deposited research ligand · no curated assay
2-[methyl(pyridin-2-yl)amino]ethan-1-ol
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
2-bromo-4-fluoro-N,N-dimethylbenzamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
2-chloro-N-methylbenzene-1-sulfonamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 2-methoxy-N-[(4-methylphenyl)methyl]acetamide](/compounds/depiction/22e66cecfba0ef5249ba-light.svg)
![Verified 2D molecular structure of 2-methoxy-N-[(4-methylphenyl)methyl]acetamide](/compounds/depiction/22e66cecfba0ef5249ba-dark.svg)
Deposited research ligand · no curated assay
2-methoxy-N-[(4-methylphenyl)methyl]acetamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)-1,2-oxazole
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
3,5-dimethyl-4-(4-pyridin-4-yl-1~{H}-pyrazol-3-yl)-1,2-oxazole
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 3-[(2S)-1-(methanesulfonyl)pyrrolidin-2-yl]-5-methyl-1,2-oxazole](/compounds/depiction/9ed27f4df1571d474e1b-light.svg)
![Verified 2D molecular structure of 3-[(2S)-1-(methanesulfonyl)pyrrolidin-2-yl]-5-methyl-1,2-oxazole](/compounds/depiction/9ed27f4df1571d474e1b-dark.svg)
Deposited research ligand · no curated assay
3-[(2S)-1-(methanesulfonyl)pyrrolidin-2-yl]-5-methyl-1,2-oxazole
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
3-cyclohexyl-1-(morpholin-4-yl)propan-1-one
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
4-(3-methyl-5-phenyl-imidazol-4-yl)pyridine
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
4-(dipropylamino)butanenitrile
DNMT3B
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 4-[(5-chloro-1,2,3-thiadiazol-4-yl)methyl]morpholine](/compounds/depiction/5dae89c55c7fc52ac947-light.svg)
![Verified 2D molecular structure of 4-[(5-chloro-1,2,3-thiadiazol-4-yl)methyl]morpholine](/compounds/depiction/5dae89c55c7fc52ac947-dark.svg)
Deposited research ligand · no curated assay
4-[(5-chloro-1,2,3-thiadiazol-4-yl)methyl]morpholine
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 4-[5-(7-fluoranylquinolin-4-yl)-1-methyl-imidazol-4-yl]-3,5-dimethyl-1,2-oxazole](/compounds/depiction/a777f153aedb74c06a50-light.svg)
![Verified 2D molecular structure of 4-[5-(7-fluoranylquinolin-4-yl)-1-methyl-imidazol-4-yl]-3,5-dimethyl-1,2-oxazole](/compounds/depiction/a777f153aedb74c06a50-dark.svg)
Deposited research ligand · no curated assay
4-[5-(7-fluoranylquinolin-4-yl)-1-methyl-imidazol-4-yl]-3,5-dimethyl-1,2-oxazole
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 4-[5-[4-(aminomethyl)-2,6-dimethoxy-phenyl]-3-methyl-imidazol-4-yl]benzenecarbonitrile](/compounds/depiction/ca5b2ddaf0e2a46c0f12-light.svg)
![Verified 2D molecular structure of 4-[5-[4-(aminomethyl)-2,6-dimethoxy-phenyl]-3-methyl-imidazol-4-yl]benzenecarbonitrile](/compounds/depiction/ca5b2ddaf0e2a46c0f12-dark.svg)
Deposited research ligand · no curated assay
4-[5-[4-(aminomethyl)-2,6-dimethoxy-phenyl]-3-methyl-imidazol-4-yl]benzenecarbonitrile
NSD2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 4-[[(5-bromanylpyridin-3-yl)methylamino]methyl]aniline](/compounds/depiction/b0d16cbd3258e0c3c55c-light.svg)
![Verified 2D molecular structure of 4-[[(5-bromanylpyridin-3-yl)methylamino]methyl]aniline](/compounds/depiction/b0d16cbd3258e0c3c55c-dark.svg)
Deposited research ligand · no curated assay
4-[[(5-bromanylpyridin-3-yl)methylamino]methyl]aniline
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Source identityDepiction not verified
Source SMILES and full InChIKey require reconciliation.
Deposited research ligand · no curated assay
4-[[cyclopropyl-[(~{Z})-2-methyl-4-(5-oxidanylidene-2~{H}-1,4-oxazin-3-yl)but-3-enoyl]amino]methyl]-~{N}-[3-[2-[[4-(hydroxymethyl)phenyl]carbonyl-methyl-amino]ethyl]phenyl]benzamide
NSD2
Source verification is pending.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
4-bromo-1H-pyrazole
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
4-IODOPYRAZOLE
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 4-methyl-3-[1-methyl-5-(3-oxidanylidene-4~{H}-1,4-benzoxazin-7-yl)imidazol-4-yl]-~{N}-phenyl-benzamide](/compounds/depiction/a578d43c942507209461-light.svg)
![Verified 2D molecular structure of 4-methyl-3-[1-methyl-5-(3-oxidanylidene-4~{H}-1,4-benzoxazin-7-yl)imidazol-4-yl]-~{N}-phenyl-benzamide](/compounds/depiction/a578d43c942507209461-dark.svg)
Deposited research ligand · no curated assay
4-methyl-3-[1-methyl-5-(3-oxidanylidene-4~{H}-1,4-benzoxazin-7-yl)imidazol-4-yl]-~{N}-phenyl-benzamide
NSD2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 5-[2-hydroxyethyl(propyl)amino]pentan-1-ol](/compounds/depiction/41e85265c0f4698217d1-light.svg)
![Verified 2D molecular structure of 5-[2-hydroxyethyl(propyl)amino]pentan-1-ol](/compounds/depiction/41e85265c0f4698217d1-dark.svg)
Deposited research ligand · no curated assay
5-[2-hydroxyethyl(propyl)amino]pentan-1-ol
DNMT3B
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
5-bromanylpyrimidine
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
5-methyl-2-piperidin-4-yl-6-pyridin-4-yl-pyridazin-3-one
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
5-methyl-6-phenyl-2-piperidin-4-yl-pyridazin-3-one
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
6-dipropylamino-1-hexanol
DNMT3B
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 6-methyl-2-[(3-methyl-1,2-oxazol-5-yl)methyl]pyridazin-3(2H)-one](/compounds/depiction/061ab37d5b735ee7dc60-light.svg)
![Verified 2D molecular structure of 6-methyl-2-[(3-methyl-1,2-oxazol-5-yl)methyl]pyridazin-3(2H)-one](/compounds/depiction/061ab37d5b735ee7dc60-dark.svg)
Deposited research ligand · no curated assay
6-methyl-2-[(3-methyl-1,2-oxazol-5-yl)methyl]pyridazin-3(2H)-one
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 6-methyl-N-{[(3S)-pyrrolidin-3-yl]methyl}pyridin-2-amine](/compounds/depiction/e4ca19f54808ecb689ca-light.svg)
![Verified 2D molecular structure of 6-methyl-N-{[(3S)-pyrrolidin-3-yl]methyl}pyridin-2-amine](/compounds/depiction/e4ca19f54808ecb689ca-dark.svg)
Deposited research ligand · no curated assay
6-methyl-N-{[(3S)-pyrrolidin-3-yl]methyl}pyridin-2-amine
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 7-[3-methyl-5-[2-methyl-5-[(pyridin-3-ylamino)methyl]phenyl]imidazol-4-yl]-4~{H}-1,4-benzoxazin-3-one](/compounds/depiction/45b68058cab2707d148a-light.svg)
![Verified 2D molecular structure of 7-[3-methyl-5-[2-methyl-5-[(pyridin-3-ylamino)methyl]phenyl]imidazol-4-yl]-4~{H}-1,4-benzoxazin-3-one](/compounds/depiction/45b68058cab2707d148a-dark.svg)
Deposited research ligand · no curated assay
7-[3-methyl-5-[2-methyl-5-[(pyridin-3-ylamino)methyl]phenyl]imidazol-4-yl]-4~{H}-1,4-benzoxazin-3-one
NSD2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 7-[5-methyl-3-[2-methyl-5-(piperidin-1-ylmethyl)phenyl]-1,2-oxazol-4-yl]-4~{H}-1,4-benzoxazin-3-one](/compounds/depiction/18f1bcef217c83788503-light.svg)
![Verified 2D molecular structure of 7-[5-methyl-3-[2-methyl-5-(piperidin-1-ylmethyl)phenyl]-1,2-oxazol-4-yl]-4~{H}-1,4-benzoxazin-3-one](/compounds/depiction/18f1bcef217c83788503-dark.svg)
Deposited research ligand · no curated assay
7-[5-methyl-3-[2-methyl-5-(piperidin-1-ylmethyl)phenyl]-1,2-oxazol-4-yl]-4~{H}-1,4-benzoxazin-3-one
NSD2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
methanone](/compounds/depiction/e83ca2ed7b5cdf66c6ec-light.svg)
methanone](/compounds/depiction/e83ca2ed7b5cdf66c6ec-dark.svg)
Deposited research ligand · no curated assay
[(2R)-2-methylpiperidin-1-yl](4-methyl-1,3-thiazol-5-yl)methanone
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Source identityDepiction not verified
Source SMILES and full InChIKey require reconciliation.
Deposited research ligand · no curated assay
[(3S)-1-(propan-2-yl)piperidin-3-yl]methanol
HDGFL2
Source verification is pending.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of [3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)phenyl]methanamine](/compounds/depiction/feba6300aa726bcedcc9-light.svg)
![Verified 2D molecular structure of [3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)phenyl]methanamine](/compounds/depiction/feba6300aa726bcedcc9-dark.svg)
Deposited research ligand · no curated assay
[3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)phenyl]methanamine
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of [3-[(5-bromanylpyridin-3-yl)methylamino]phenyl]methanol](/compounds/depiction/f7bdf037eb6c69e36010-light.svg)
![Verified 2D molecular structure of [3-[(5-bromanylpyridin-3-yl)methylamino]phenyl]methanol](/compounds/depiction/f7bdf037eb6c69e36010-dark.svg)
Deposited research ligand · no curated assay
[3-[(5-bromanylpyridin-3-yl)methylamino]phenyl]methanol
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of [4-methyl-6-(piperidin-1-yl)pyrimidin-2-yl]methanol](/compounds/depiction/22896a7f9ac93e9d71ba-light.svg)
![Verified 2D molecular structure of [4-methyl-6-(piperidin-1-yl)pyrimidin-2-yl]methanol](/compounds/depiction/22896a7f9ac93e9d71ba-dark.svg)
Deposited research ligand · no curated assay
[4-methyl-6-(piperidin-1-yl)pyrimidin-2-yl]methanol
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
CHOLINE ION
DNMT3B
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
Ethambutol
DNMT3B
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
isoquinoline-3-carboxylic acid
BRD1BRPF1
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations2 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
N,N,3,5-tetramethyl-1H-pyrazole-4-sulfonamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
N,N-diethyl-2-methylbenzamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
N,N-dimethylmorpholine-4-sulfonamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
N,N-dimethylpiperazine-1-carboxamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
N,N-dimethylpyridine-3-sulfonamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
N-(2-fluorophenyl)ethanesulfonamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
N-(2-methoxyphenyl)-2-selanyl-benzamide
NSD2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
N-(4-acetylphenyl)-2-(pyrrolidin-1-yl)acetamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of N-[(1S)-1-(pyridin-3-yl)ethyl]cyclopropanamine](/compounds/depiction/b8e03b6640b8d4e165f7-light.svg)
![Verified 2D molecular structure of N-[(1S)-1-(pyridin-3-yl)ethyl]cyclopropanamine](/compounds/depiction/b8e03b6640b8d4e165f7-dark.svg)
Deposited research ligand · no curated assay
N-[(1S)-1-(pyridin-3-yl)ethyl]cyclopropanamine
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of N-[(3R)-1,1-dioxo-1lambda~6~-thiolan-3-yl]-N-methyl-N'-propan-2-ylurea](/compounds/depiction/071f233e0ea93d721b58-light.svg)
![Verified 2D molecular structure of N-[(3R)-1,1-dioxo-1lambda~6~-thiolan-3-yl]-N-methyl-N'-propan-2-ylurea](/compounds/depiction/071f233e0ea93d721b58-dark.svg)
Deposited research ligand · no curated assay
N-[(3R)-1,1-dioxo-1lambda~6~-thiolan-3-yl]-N-methyl-N'-propan-2-ylurea
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of N-[(3S)-piperidin-3-yl]benzamide](/compounds/depiction/158bc3d67e95393d04c7-light.svg)
![Verified 2D molecular structure of N-[(3S)-piperidin-3-yl]benzamide](/compounds/depiction/158bc3d67e95393d04c7-dark.svg)
Deposited research ligand · no curated assay
N-[(3S)-piperidin-3-yl]benzamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of N-[(piperidin-4-yl)methyl]methanesulfonamide](/compounds/depiction/0b90dc5e2c0125865c4b-light.svg)
![Verified 2D molecular structure of N-[(piperidin-4-yl)methyl]methanesulfonamide](/compounds/depiction/0b90dc5e2c0125865c4b-dark.svg)
Deposited research ligand · no curated assay
N-[(piperidin-4-yl)methyl]methanesulfonamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
N-cycloheptyl-N-methylmethanesulfonamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
N-ethyl-2-fluoro-4-(methylsulfonyl)aniline
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of N-methyl-1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)methanamine](/compounds/depiction/86c477db916885cbe1a6-light.svg)
![Verified 2D molecular structure of N-methyl-1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)methanamine](/compounds/depiction/86c477db916885cbe1a6-dark.svg)
Deposited research ligand · no curated assay
N-methyl-1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)methanamine
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
N-methyl-2-(methylsulfonyl)aniline
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
N-methyl-3-oxo-N-(propan-2-yl)piperazine-1-sulfonamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
N-methyl-N-(pyridin-3-yl)acetamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of N-methyl-N-[2-oxo-2-(piperidin-1-yl)ethyl]methanesulfonamide](/compounds/depiction/0ffbff76878a0ac133ac-light.svg)
![Verified 2D molecular structure of N-methyl-N-[2-oxo-2-(piperidin-1-yl)ethyl]methanesulfonamide](/compounds/depiction/0ffbff76878a0ac133ac-dark.svg)
Deposited research ligand · no curated assay
N-methyl-N-[2-oxo-2-(piperidin-1-yl)ethyl]methanesulfonamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of N-{(1R)-1-[(4S)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}acetamide](/compounds/depiction/8366dfdd01ed2ef6d915-light.svg)
![Verified 2D molecular structure of N-{(1R)-1-[(4S)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}acetamide](/compounds/depiction/8366dfdd01ed2ef6d915-dark.svg)
Deposited research ligand · no curated assay
N-{(1R)-1-[(4S)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}acetamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of N-{[(4R)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3-yl]methyl}propanamide](/compounds/depiction/dfbbdc5251c16cea9020-light.svg)
![Verified 2D molecular structure of N-{[(4R)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3-yl]methyl}propanamide](/compounds/depiction/dfbbdc5251c16cea9020-dark.svg)
Deposited research ligand · no curated assay
N-{[(4R)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3-yl]methyl}propanamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
N1-(2-hydroxyethyl)-2-methyl-1,2-propanediamine
DNMT3B
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
N~1~,N~1~,N~4~,N~4~-tetramethylpiperazine-1,4-dicarboxamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
Triisopropanolamine
DNMT3B
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
~{N},~{N}-dimethyl-1~{H}-pyrazole-4-sulfonamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
~{N}-(3-azanyl-2-methyl-phenyl)propanamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
~{N}-(4-aminophenyl)-2-selanyl-benzamide
NSD2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
~{N}-(4-fluorophenyl)-2-pyrrolidin-1-yl-ethanamide
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of ~{N}-cyclopropyl-~{N}-[[4-[[2-(6-oxidanylhexanoyl)-1~{H}-isoquinolin-6-yl]carbamoyl]phenyl]methyl]-3-oxidanylidene-4~{H}-1,4-benzoxazine-7-carboxamide](/compounds/depiction/4797066c0d81deced663-light.svg)
![Verified 2D molecular structure of ~{N}-cyclopropyl-~{N}-[[4-[[2-(6-oxidanylhexanoyl)-1~{H}-isoquinolin-6-yl]carbamoyl]phenyl]methyl]-3-oxidanylidene-4~{H}-1,4-benzoxazine-7-carboxamide](/compounds/depiction/4797066c0d81deced663-dark.svg)
Deposited research ligand · no curated assay
~{N}-cyclopropyl-~{N}-[[4-[[2-(6-oxidanylhexanoyl)-1~{H}-isoquinolin-6-yl]carbamoyl]phenyl]methyl]-3-oxidanylidene-4~{H}-1,4-benzoxazine-7-carboxamide
NSD2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations2 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
~{N}-methyl-1-pyridin-4-yl-methanamine
HDGFL2
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries