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Find missing coordinates, structure-free bioactivity, incomplete assay context and unresolved evolutionary relationships.

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42 domain records

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Trypanosoma brucei brucei (strain 927/4 GUTat10.1)

28H13_90 PWWP1

1 observed-core PDB entries · 2 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 0 other PDB components

no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
all atom completeness unassessed
residues without curated pairwise structural correspondence
deep phylogeny unresolved

62 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

ARID4A PWWP1

3 observed-core PDB entries · 3 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 0 other PDB components

no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
all atom completeness unassessed
residues without curated pairwise structural correspondence
deep phylogeny unresolved

24 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

ARID4B PWWP1

0 observed-core PDB entries · 4 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 0 other PDB components

no experimental coordinates
prediction without coordinates
no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
residues without curated pairwise structural correspondence
deep phylogeny unresolved

93 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

BRD1 PWWP1

3 observed-core PDB entries · 2 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 1 other PDB components

no curated domain bioactivity
no source curated studied small molecules
structures without curated bioactivity
all atom completeness unassessed
residues without curated pairwise structural correspondence
deep phylogeny unresolved

2 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

BRPF1 PWWP1

7 observed-core PDB entries · 4 predicted model records · 1 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 1 earlier studied small-molecule profiles · 4 other PDB components

bioactivity without bound structure
assay construct unresolved
assay method unresolved
all atom completeness unassessed
deep phylogeny unresolved

0 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

BRPF3 PWWP1

1 observed-core PDB entries · 3 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 1 other PDB components

no curated domain bioactivity
no source curated studied small molecules
deposited components not research ligands
no curated compound evidence
all atom completeness unassessed
deep phylogeny unresolved

0 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

DNMT3A PWWP1

14 observed-core PDB entries · 3 predicted model records · 1 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 4 other PDB components

no curated domain bioactivity
no source curated studied small molecules
deposited components not research ligands
structures without curated bioactivity
assay construct unresolved
observed core missing heavy atoms
all atom completeness unassessed
deep phylogeny unresolved

0 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

5 assessed chain/domain records have missing heavy atoms. Entries: 11OA.

Residue evidence Inspect missing atoms Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

DNMT3B PWWP1

14 observed-core PDB entries · 8 predicted model records · 2 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 1 earlier studied small-molecule profiles · 4 other PDB components

bioactivity without bound structure
assay construct unresolved
assay method unresolved
all atom completeness unassessed
deep phylogeny unresolved

0 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Mus musculus

Dnmt3b PWWP1

1 observed-core PDB entries · 4 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 0 other PDB components

no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
all atom completeness unassessed
residues without curated pairwise structural correspondence
deep phylogeny unresolved

59 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

GLYR1 PWWP1

0 observed-core PDB entries · 5 predicted model records · 1 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 1 earlier studied small-molecule profiles · 0 other PDB components

no experimental coordinates
prediction without coordinates
bioactivity without bound structure
assay construct unresolved
assay method unresolved
residues without curated pairwise structural correspondence
deep phylogeny unresolved

59 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

HDGF PWWP1

2 observed-core PDB entries · 3 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 0 other PDB components

no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
all atom completeness unassessed
deep phylogeny unresolved

0 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

HDGFL1 PWWP1

0 observed-core PDB entries · 1 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 0 other PDB components

no experimental coordinates
prediction without coordinates
no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
residues without curated pairwise structural correspondence
deep phylogeny unresolved

52 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

HDGFL2 PWWP1

86 observed-core PDB entries · 4 predicted model records · 7 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 2 earlier studied small-molecule profiles · 5 other PDB components

bioactivity without bound structure
unresolved chemical identity
assay construct unresolved
all atom completeness unassessed
deep phylogeny unresolved

0 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

HDGFL3 PWWP1

5 observed-core PDB entries · 1 predicted model records · 1 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 1 earlier studied small-molecule profiles · 4 other PDB components

deposited components not research ligands
bioactivity without bound structure
assay construct unresolved
assay method unresolved
all atom completeness unassessed
deep phylogeny unresolved

0 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Rattus norvegicus

Hdgf PWWP1

3 observed-core PDB entries · 1 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 1 other PDB components

no curated domain bioactivity
no source curated studied small molecules
deposited components not research ligands
no curated compound evidence
all atom completeness unassessed
residues without curated pairwise structural correspondence
deep phylogeny unresolved

58 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Mus musculus

Hdgfl3 PWWP1

no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
all atom completeness unassessed
residues without curated pairwise structural correspondence
deep phylogeny unresolved

58 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

IOC4 PWWP1

1 observed-core PDB entries · 1 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 0 other PDB components

no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
all atom completeness unassessed
residues without curated pairwise structural correspondence
deep phylogeny unresolved

151 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

JMJD1C PWWP1

0 observed-core PDB entries · 3 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 0 other PDB components

no experimental coordinates
prediction without coordinates
no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
residues without curated pairwise structural correspondence
predicted candidate excluded from tree

99 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Drosophila melanogaster

Jasper PWWP1

4 observed-core PDB entries · 1 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 1 other PDB components

no curated domain bioactivity
no source curated studied small molecules
deposited components not research ligands
structures without curated bioactivity
all atom completeness unassessed
residues without curated pairwise structural correspondence
deep phylogeny unresolved

52 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

KDM3A PWWP1

no experimental coordinates
prediction without coordinates
no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
residues without curated pairwise structural correspondence
predicted candidate excluded from tree

90 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

KDM3B PWWP1

no experimental coordinates
prediction without coordinates
no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
residues without curated pairwise structural correspondence
predicted candidate excluded from tree

99 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

MBD5 PWWP1

0 observed-core PDB entries · 2 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 0 other PDB components

no experimental coordinates
prediction without coordinates
no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
residues without curated pairwise structural correspondence
deep phylogeny unresolved

25 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

MSH6 PWWP1

2 observed-core PDB entries · 4 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 2 other PDB components

no curated domain bioactivity
no source curated studied small molecules
deposited components not research ligands
no curated compound evidence
all atom completeness unassessed
deep phylogeny unresolved

0 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

NSD1 PWWP1

no experimental coordinates
prediction without coordinates
no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
residues without curated pairwise structural correspondence
deep phylogeny unresolved

66 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

NSD1 PWWP2

no experimental coordinates
prediction without coordinates
no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
residues without curated pairwise structural correspondence
deep phylogeny unresolved

63 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

NSD2 PWWP1

19 observed-core PDB entries · 7 predicted model records · 34 Phase 5/6A domain observations + 2 Phase 6B exact-domain source observations · 17 earlier studied small-molecule profiles · 5 other PDB components

bioactivity without bound structure
unresolved chemical identity
assay construct unresolved
observed core missing heavy atoms
all atom completeness unassessed
deep phylogeny unresolved

0 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

3 assessed chain/domain records have missing heavy atoms. Entries: 6XCG.

Residue evidence Inspect missing atoms Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

NSD2 PWWP2

0 observed-core PDB entries · 7 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 1 other PDB components

no experimental coordinates
prediction without coordinates
no curated domain bioactivity
no source curated studied small molecules
deposited components not research ligands
no curated compound evidence
all atom completeness unassessed
residues without curated pairwise structural correspondence
deep phylogeny unresolved

63 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

NSD3 PWWP1

11 observed-core PDB entries · 5 predicted model records · 13 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 11 earlier studied small-molecule profiles · 1 other PDB components

bioactivity without bound structure
unresolved chemical identity
assay construct unresolved
source conflict
all atom completeness unassessed
deep phylogeny unresolved

0 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

NSD3 PWWP2

2 observed-core PDB entries · 5 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 1 other PDB components

no curated domain bioactivity
no source curated studied small molecules
deposited components not research ligands
no curated compound evidence
all atom completeness unassessed
deep phylogeny unresolved

0 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

PSIP1 PWWP1

13 observed-core PDB entries · 3 predicted model records · 2 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 1 earlier studied small-molecule profiles · 4 other PDB components

deposited components not research ligands
bioactivity without bound structure
unresolved chemical identity
assay construct unresolved
all atom completeness unassessed
residues without curated pairwise structural correspondence
deep phylogeny unresolved

3 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

PWWP2A PWWP1

no experimental coordinates
prediction without coordinates
no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
residues without curated pairwise structural correspondence
deep phylogeny unresolved

61 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

PWWP2B PWWP1

no curated domain bioactivity
no source curated studied small molecules
deposited components not research ligands
no curated compound evidence
all atom completeness unassessed
residues without curated pairwise structural correspondence
deep phylogeny unresolved

2 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

PWWP3A PWWP1

no curated domain bioactivity
no source curated studied small molecules
deposited components not research ligands
no curated compound evidence
all atom completeness unassessed
residues without curated pairwise structural correspondence
deep phylogeny unresolved

3 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

PWWP3B PWWP1

no experimental coordinates
prediction without coordinates
no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
residues without curated pairwise structural correspondence
deep phylogeny unresolved

62 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

PWWP4 PWWP1

no experimental coordinates
prediction without coordinates
no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
residues without curated pairwise structural correspondence
deep phylogeny unresolved

62 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

ZCWPW1 PWWP1

0 observed-core PDB entries · 5 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 0 other PDB components

no experimental coordinates
prediction without coordinates
no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
residues without curated pairwise structural correspondence
deep phylogeny unresolved

67 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

ZCWPW2 PWWP1

no experimental coordinates
prediction without coordinates
no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
residues without curated pairwise structural correspondence
deep phylogeny unresolved

65 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

ZMYND11 PWWP1

1 observed-core PDB entries · 6 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 0 other PDB components

no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
all atom completeness unassessed
deep phylogeny unresolved

0 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Homo sapiens

ZMYND8 PWWP1

5 observed-core PDB entries · 23 predicted model records · 0 Phase 5/6A domain observations + 0 Phase 6B exact-domain source observations · 0 earlier studied small-molecule profiles · 4 other PDB components

no curated domain bioactivity
no source curated studied small molecules
deposited components not research ligands
no curated compound evidence
all atom completeness unassessed
deep phylogeny unresolved

0 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Mus musculus

Zmynd11 PWWP1

no curated domain bioactivity
no source curated studied small molecules
deposited components not research ligands
no curated compound evidence
all atom completeness unassessed
residues without curated pairwise structural correspondence
deep phylogeny unresolved

52 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

pdp1 PWWP1

no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
all atom completeness unassessed
residues without curated pairwise structural correspondence
deep phylogeny unresolved

63 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

pdp2 PWWP1

no curated domain bioactivity
no source curated studied small molecules
no curated compound evidence
all atom completeness unassessed
residues without curated pairwise structural correspondence
deep phylogeny unresolved

65 annotated positions lack a retained pairwise structural correspondence. This concerns representative-core comparisons, not all experimental coordinates.

Residue evidence Chemical evidence Domain landscape Comprehensive structure QA

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