E3 Recruiter Builder

Design and explore E3 ligase recruiter compounds with intuitive visualization tools.

Ligase

Scaffold Class

Recruiter Class

Min QED QED — Quantitative Estimate of Drug-likeness (0–1). Combines key physicochemical metrics.

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QED ≥ 0.00 ⓘ

Quantitative Estimate of Drug-likeness (QED): combines molecular weight, lipophilicity (LogP), polar surface area, hydrogen bond counts, and rotatable bonds into a 0–1 score (higher = more drug-like).

MW ≥ 0

Advanced Filters

Max LogP (lipophilicity)

Max TPSA (Å²)

Max HBA (hydrogen bond acceptors)

Max HBD (hydrogen bond donors)

Max Rotatable Bonds

Min Fsp³ (0–1, higher = more 3D)

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