PWWP family explorer

Find a domain. Understand its evidence.

42 native annotation cores across 39 proteins, including 33 cores across 30 human records.

Human annotation-core coverage

18 of 33 domains have observed coordinates

Observed in the snapshotNo observed coordinates

Annotation and observation are distinct. 27 human proteins have annotation-supported assignments. KDM3A, KDM3B and JMJD1C remain predicted PWWP-like candidates.

Source annotation intervals are not certified whole-domain or pocket boundaries. Selected nonhuman comparators are not an exhaustive species inventory. Canonical AlphaFold records are available for all 42 cores in this snapshot.

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Native domains

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Gene, accession or domain

Species scope

Annotation tier

Coordinates

42 of 42 annotation cores shown

ARID4A PWWP1

Homo sapiens

Annotation supported

P29374 · 170–262 · 93 residues

3PDB entries with observed core coordinates

Protein and species	Native domain	Canonical interval	Observed entries	Assignment
ARID4A Homo sapiens	PWWP1	170–262 93 residues	3	annotation supported
ARID4B Homo sapiens	PWWP1	170–262 93 residues	0	annotation supported
BRD1 Homo sapiens	PWWP1	929–1012 84 residues	3	annotation supported
BRPF1 Homo sapiens	PWWP1	1085–1168 84 residues	7	annotation supported
BRPF3 Homo sapiens	PWWP1	1076–1159 84 residues	1	annotation supported
DNMT3A Homo sapiens	PWWP1	292–350 59 residues	14	annotation supported
DNMT3B Homo sapiens	PWWP1	225–283 59 residues	14	annotation supported
GLYR1 Homo sapiens	PWWP1	8–66 59 residues	0	annotation supported
HDGF Homo sapiens	PWWP1	12–69 58 residues	2	annotation supported
HDGFL1 Homo sapiens	PWWP1	11–62 52 residues	0	annotation supported
HDGFL2 Homo sapiens	PWWP1	7–64 58 residues	86	annotation supported
HDGFL3 Homo sapiens	PWWP1	11–68 58 residues	5	annotation supported
JMJD1C Homo sapiens	PWWP1	81–179 99 residues	0	predicted PWWP like
KDM3A Homo sapiens	PWWP1	88–177 90 residues	0	predicted PWWP like
KDM3B Homo sapiens	PWWP1	90–188 99 residues	0	predicted PWWP like
MBD5 Homo sapiens	PWWP1	1385–1409 25 residues	0	annotation supported
MSH6 Homo sapiens	PWWP1	92–154 63 residues	2	annotation supported
NSD1 Homo sapiens	PWWP1	323–388 66 residues	0	annotation supported
NSD1 Homo sapiens	PWWP2	1756–1818 63 residues	0	annotation supported
NSD2 Homo sapiens	PWWP1	222–286 65 residues	19	annotation supported
NSD2 Homo sapiens	PWWP2	880–942 63 residues	0	annotation supported
NSD3 Homo sapiens	PWWP1	270–333 64 residues	11	annotation supported
NSD3 Homo sapiens	PWWP2	960–1022 63 residues	2	annotation supported
PSIP1 Homo sapiens	PWWP1	1–64 64 residues	13	annotation supported
PWWP2A Homo sapiens	PWWP1	655–715 61 residues	0	annotation supported
PWWP2B Homo sapiens	PWWP1	490–550 61 residues	1	annotation supported
PWWP3A Homo sapiens	PWWP1	411–472 62 residues	1	annotation supported
PWWP3B Homo sapiens	PWWP1	392–453 62 residues	0	annotation supported
PWWP4 Homo sapiens	PWWP1	1756–1817 62 residues	0	annotation supported
ZCWPW1 Homo sapiens	PWWP1	317–383 67 residues	0	annotation supported
ZCWPW2 Homo sapiens	PWWP1	98–162 65 residues	0	annotation supported
ZMYND11 Homo sapiens	PWWP1	280–331 52 residues	1	annotation supported
ZMYND8 Homo sapiens	PWWP1	277–327 51 residues	5	annotation supported
Jasper Drosophila melanogaster	PWWP1	12–63 52 residues	4	annotation supported
IOC4 Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	PWWP1	10–160 151 residues	1	annotation supported
pdp1 Schizosaccharomyces pombe (strain 972 / ATCC 24843)	PWWP1	52–114 63 residues	1	annotation supported
pdp2 Schizosaccharomyces pombe (strain 972 / ATCC 24843)	PWWP1	125–189 65 residues	1	annotation supported
28H13_90 Trypanosoma brucei brucei (strain 927/4 GUTat10.1)	PWWP1	7–68 62 residues	1	annotation supported
Hdgf Rattus norvegicus	PWWP1	12–69 58 residues	3	annotation supported
Dnmt3b Mus musculus	PWWP1	232–290 59 residues	1	annotation supported
Hdgfl3 Mus musculus	PWWP1	11–68 58 residues	1	annotation supported
Zmynd11 Mus musculus	PWWP1	280–331 52 residues	3	annotation supported

Find a domain. Understand its evidence.

18 of 33 domains have observed coordinates

Native domains

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Complete domain inventory