STRUCTURAL BIOLOGY & CHEMICAL EVIDENCEDataset v1.2 · Phase 6D · Comparative experimental recognition environments

Provenance & attribution

Source references

Follow bibliographic and deposition records to their primary sources.

Bibliographic and deposition sources retain their individual verification scope. A PDB citation may describe an unpublished deposition; inclusion is not a claim that the full publication has been scientifically reviewed.

SourcePublication or depositionVerification
PMID:42503659
2026
AI-Driven Discovery of a Hydrophobic-Tag Degrader Targeting NSD3 for Lung Squamous Carcinoma Therapy.
Journal of medicinal chemistry
10.1021/acs.jmedchem.6c00983
bibliographic_metadata_and_abstract_verified
PMID:42444282
2026
Computational analysis of non-synonymous SNPs-induced structural perturbations and histone binding alterations in the PWWP domain of PWWP2A and PWWP2B proteins.
Journal of biomolecular structure & dynamics
10.1080/07391102.2026.2698738
bibliographic_metadata_and_abstract_verified
REF:PDB:9S28:primary
2026
Core nucleosomes are refractory to lentiviral DNA integration.
Nat Commun
10.1038/s41467-026-76698-8
PDB citation metadata; original paper not independently reviewed unless curated record is linked
PMID:42489162
2026
De novo design of proteinaceous binders targeting the LEDGF PWWP domain.
Protein science : a publication of the Protein Society
10.1002/pro.70726
primary_abstract_and_data_availability_verified
PMID:42442058
2026
Discovery and biological evaluation of HS13 as a novel covalent ligand targeting the NSD2-PWWP1 domain.
Bioorganic & medicinal chemistry
10.1016/j.bmc.2026.118751
bibliographic_metadata_and_abstract_verified
PMID:41820229
2026
Fluorogenic Ligand Enables Identification of NSD3-Overexpressed Tumors by Targeting the PWWP1 Domain of NSD3.
Analytical chemistry
10.1021/acs.analchem.5c07785
bibliographic_metadata_and_abstract_verified
PMID:42194065
2026
High-Affinity Nanobody Against the LEDGF PWWP Domain Inhibits Chromatin Binding In Vitro.
Biomolecules
10.3390/biom16050716
primary_full_text_sections_verified
REF:PDB:9MP0:primary
2026
Mechanisms of DNMT3A-3L-mediated de novo DNA methylation on chromatin.
Nat.Struct.Mol.Biol.
10.1038/s41594-025-01704-4
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:9LQ1:primary
2026
Molecular basis for the inhibition of de novo DNA methylation by TCL1A.
Nat Commun
10.1038/s41467-025-67710-8
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:11NZ:primary
2026
Multidomain interaction governs the filamentous assembly of the dominant-negative DNMT3A R882H mutant.
Proc.Natl.Acad.Sci.USA
10.1073/pnas.2609226123
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:9Y60:primary
2026
NSD2 degradation remediates the oncogenic cistrome in t(4;14) multiple myeloma.
Blood
10.1182/blood.2025031998
PDB citation metadata; original paper not independently reviewed unless curated record is linked
PMID:41742418
2026
Nucleosome spacing regulates linker methylation by DNMT3A2/3B3.
Molecular cell
10.1016/j.molcel.2026.01.030
bibliographic_metadata_and_abstract_verified
REF:PDB:29HG:primary
2026
Structural basis of NSD2 degradation via targeted recruitment of SCF-FBXO22.
Nat Commun
10.1038/s41467-026-72235-9
PDB citation metadata; original paper not independently reviewed unless curated record is linked
PMID:41708613
2026
Structural insight into hierarchical DNMT3A autoinhibition and its dysregulation in disease.
Nature communications
10.1038/s41467-026-69563-1
primary_full_text_sections_verified
REF:PDB:9XYC:primary
2026
Structure and function of IWS1 in transcription elongation.
Nucleic Acids Res.
10.1093/nar/gkag357
PDB citation metadata; original paper not independently reviewed unless curated record is linked
PMID:40709919
2025
Crystal engineering of the hepatoma-derived growth factor-related protein 2 PWWP domain towards crystallographic fragment screening.
Acta crystallographica. Section F, Structural biology communications
10.1107/s2053230x25006302
primary_full_text_sections_verified
REF:PDB:9KN9:primary
2025
Fragment-Based Screening of NSD2-PWWP1 Identifies Novel Covalent Allosteric Ligands That Diminish Methyllysine and DNA Binding Abilities of NSD2.
J.Med.Chem.
10.1021/acs.jmedchem.5c01902
PDB citation metadata; original paper not independently reviewed unless curated record is linked
PMID:40138405
2025
Histone modification-driven structural remodeling unleashes DNMT3B in DNA methylation.
Science advances
10.1126/sciadv.adu8116
primary_full_text_sections_verified
PMID:40959233
2025
Structural and Molecular Insight into the PWWP1 Domain of NSD2 from the Discovery of Novel Binders Via DNA-Encoded Library Screening.
ACS medicinal chemistry letters
10.1021/acsmedchemlett.5c00396
primary_full_text_sections_verified
PMID:40089621
2025
Structural basis of thymidine-rich DNA recognition by Drosophila P75 PWWP domain.
Communications biology
10.1038/s42003-025-07895-2
primary_full_text_sections_verified
PMID:38687638
2024
Discovery of LLC0424 as a Potent and Selective in Vivo NSD2 PROTAC Degrader.
Journal of medicinal chemistry
10.1021/acs.jmedchem.3c01765
full_text_retrieved_metadata_verified_claims_pending
PMID:39031937
2024
Fragment-based discovery of small molecule inhibitors of the HDGFRP2 PWWP domain.
FEBS letters
10.1002/1873-3468.14981
primary_full_text_sections_verified
REF:PDB:9EXW:primary
2024
Identification of Novel Potent NSD2-PWWP1 Ligands Using Structure-Based Design and Computational Approaches.
J.Med.Chem.
10.1021/acs.jmedchem.4c00215
PDB citation metadata; original paper not independently reviewed unless curated record is linked
PMID:39413441
2024
Inhibitors targeting the PWWP domain-containing proteins.
European journal of medicinal chemistry
10.1016/j.ejmech.2024.116965
bibliographic_metadata_and_abstract_verified
PMID:39461037
2024
Rational fragment-based design of compounds targeting the PWWP domain of the HRP family.
European journal of medicinal chemistry
10.1016/j.ejmech.2024.116960
bibliographic_metadata_and_abstract_verified
REF:PDB:8QZM:primary
2024
The N-terminal region of DNMT3A engages the nucleosome surface to aid chromatin recruitment.
Embo Rep.
10.1038/s44319-024-00306-3
PDB citation metadata; original paper not independently reviewed unless curated record is linked
PMID:36976643
2023
Discovery of a Potent and Selective Targeted NSD2 Degrader for the Reduction of H3K36me2.
Journal of the American Chemical Society
10.1021/jacs.3c01421
bibliographic_metadata_and_abstract_verified
PMID:37615563
2023
Multivalency of nucleosome recognition by LEDGF.
Nucleic acids research
10.1093/nar/gkad674
primary_full_text_sections_verified
REF:PDB:8EIH:primary
2023
Structural basis for the allosteric regulation and dynamic assembly of DNMT3B.
Nucleic Acids Res.
10.1093/nar/gkad972
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:8AG6:primary
2023
Unexpected moves: a conformational change in MutS alpha enables high-affinity DNA mismatch binding.
Nucleic Acids Res.
10.1093/nar/gkad015
PDB citation metadata; original paper not independently reviewed unless curated record is linked
PMID:34782742
2022
A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization.
Nature chemical biology
10.1038/s41589-021-00898-0
primary_full_text_sections_verified
PDB:7V8N
2022
Crystal structure of the PWWP-ARID of ARID4A
Journal not recorded in this snapshot
10.2210/pdb7V8N/pdb
authoritative_structural_metadata_verified
PMID:35895319
2022
Discovery of a First-in-Class Degrader for Nuclear Receptor Binding SET Domain Protein 2 (NSD2) and Ikaros/Aiolos.
Journal of medicinal chemistry
10.1021/acs.jmedchem.2c00807
bibliographic_metadata_and_abstract_verified
PMID:35717870
2022
Discovery of a potent and selective proteolysis targeting chimera (PROTAC) degrader of NSD3 histone methyltransferase.
European journal of medicinal chemistry
10.1016/j.ejmech.2022.114528
bibliographic_metadata_and_abstract_verified
REF:PDB:7E29:primary
2022
H3K36 methylation and DNA-binding both promote Ioc4 recruitment and Isw1b remodeler function.
Nucleic Acids Res.
10.1093/nar/gkac077
PDB citation metadata; original paper not independently reviewed unless curated record is linked
PMID:35704853
2022
Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors.
Journal of medicinal chemistry
10.1021/acs.jmedchem.2c00709
bibliographic_metadata_and_abstract_verified
PMID:33556623
2021
Crystal structure of the BRPF2 PWWP domain in complex with DNA reveals a different binding mode than the HDGF family of PWWP domains.
Biochimica et biophysica acta. Gene regulatory mechanisms
10.1016/j.bbagrm.2021.194688
bibliographic_metadata_and_abstract_verified
PMID:33522809
2021
Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2.
Journal of medicinal chemistry
10.1021/acs.jmedchem.0c01768
primary_full_text_sections_verified
PMID:34271259
2021
Histone and DNA binding ability studies of the NSD subfamily of PWWP domains.
Biochemical and biophysical research communications
10.1016/j.bbrc.2021.07.017
bibliographic_metadata_and_abstract_verified
REF:PDB:7CRO:primary
2021
Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.
Nature
10.1038/s41586-020-03069-8
PDB citation metadata; original paper not independently reviewed unless curated record is linked
PMID:34506790
2021
Structural Insight into Chromatin Recognition by Multiple Domains of the Tumor Suppressor RBBP1.
Journal of molecular biology
10.1016/j.jmb.2021.167224
primary_full_text_sections_verified
REF:PDB:7OUF:primary
2021
Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures.
Nat Commun
10.1038/s41467-021-25284-1
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:7PEL:primary
2020
Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56gamma.
Nat Commun
10.1038/s41467-020-18874-y
PDB citation metadata; original paper not independently reviewed unless curated record is linked
PMID:31819277
2020
Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding.
Nature structural & molecular biology
10.1038/s41594-019-0345-4
primary_full_text_sections_verified
PMID:32968275
2020
Structure of nucleosome-bound DNA methyltransferases DNMT3A and DNMT3B.
Nature
10.1038/s41586-020-2747-1
bibliographic_metadata_and_abstract_verified
REF:PDB:6IIP:primary
2019
Apo-form structure of the HRP3 PWWP domain
Nucleic Acids Res.
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:6IIR:primary
2019
Complex structure of the HRP3 PWWP domain with a 10-bp GC-rich DNA
Nucleic Acids Res.
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:6IIQ:primary
2019
Complex structure of the HRP3 PWWP domain with a 16-bp TA-rich DNA
Nucleic Acids Res.
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:6IIT:primary
2019
Complex structure of the HRP3 PWWP domain with both a 16-bp TA-rich DNA and a H3K36me2-containing histone peptide
Nucleic Acids Res.
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:6IIS:primary
2019
Complex structure of the HRP3 PWWP domain with both a 16-bp TA-rich DNA and an H3K36me3-containing histone peptide
Nucleic Acids Res.
PDB citation metadata; original paper not independently reviewed unless curated record is linked
PMID:31285596
2019
Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3.
Nature chemical biology
10.1038/s41589-019-0310-x
primary_data_availability_and_developer_assays_verified
PMID:31634469
2019
H3K36me2/3 Binding and DNA Binding of the DNA Methyltransferase DNMT3A PWWP Domain Both Contribute to its Chromatin Interaction.
Journal of molecular biology
10.1016/j.jmb.2019.09.006
bibliographic_metadata_and_abstract_verified
PMID:31616795
2019
LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells.
Science advances
10.1126/sciadv.aay3068
full_text_retrieved_metadata_verified_claims_pending
REF:PDB:29HG:1
2019
Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
Acta Crystallogr., Sect. D: Biol. Crystallogr.
10.1107/S2059798319011471
PDB citation metadata; original paper not independently reviewed unless curated record is linked
PMID:30666492
2019
Resonance assignments for the tandem PWWP-ARID domains of human RBBP1.
Biomolecular NMR assignments
10.1007/s12104-019-09873-2
bibliographic_metadata_and_abstract_verified
PMID:30626613
2019
Solution structure of TbTFIIS2-2 PWWP domain from Trypanosoma brucei and its binding to H4K17me3 and H3K32me3.
The Biochemical journal
10.1042/bcj20180870
bibliographic_metadata_and_abstract_verified
PMID:31162607
2019
The HRP3 PWWP domain recognizes the minor groove of double-stranded DNA and recruits HRP3 to chromatin.
Nucleic acids research
10.1093/nar/gkz294
primary_full_text_sections_verified
PMID:30228260
2018
A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes.
Nature communications
10.1038/s41467-018-06235-9
full_text_retrieved_metadata_verified_claims_pending
PMID:29321480
2018
Domain swapping and SMYD1 interactions with the PWWP domain of human hepatoma-derived growth factor.
Scientific reports
10.1038/s41598-017-18510-8
primary_full_text_sections_verified
PMID:30327463
2018
PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex.
Nature communications
10.1038/s41467-018-06665-5
primary_full_text_sections_verified
PMID:28645917
2017
Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation.
The EMBO journal
10.15252/embj.201695757
bibliographic_metadata_and_abstract_verified
PMID:28966017
2017
The Structure of the ZMYND8/Drebrin Complex Suggests a Cytoplasmic Sequestering Mechanism of ZMYND8 by Drebrin.
Structure (London, England : 1993)
10.1016/j.str.2017.08.014
bibliographic_metadata_and_abstract_verified
PMID:26912663
2016
A PWWP Domain of Histone-Lysine N-Methyltransferase NSD2 Binds to Dimethylated Lys-36 of Histone H3 and Regulates NSD2 Function at Chromatin.
The Journal of biological chemistry
10.1074/jbc.m116.720748
bibliographic_metadata_and_abstract_verified
PMID:27926874
2016
Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin.
Cell reports
10.1016/j.celrep.2016.11.014
primary_full_text_sections_verified
PMID:28510146
2016
PWWP domains and their modes of sensing DNA and histone methylated lysines.
Biophysical reviews
10.1007/s12551-015-0190-6
bibliographic_metadata_and_abstract_verified
PMID:26655721
2016
Selective Recognition of H3.1K36 Dimethylation/H4K16 Acetylation Facilitates the Regulation of All-trans-retinoic Acid (ATRA)-responsive Genes by Putative Chromatin Reader ZMYND8.
The Journal of biological chemistry
10.1074/jbc.m115.679985
bibliographic_metadata_and_abstract_verified
PMID:27005948
2016
Solution structure of TbTFIIS2-1 PWWP domain from Trypanosoma brucei.
Proteins
10.1002/prot.25035
bibliographic_metadata_and_abstract_verified
PMID:26993463
2016
Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B.
Journal of structural biology
10.1016/j.jsb.2016.03.013
bibliographic_metadata_and_abstract_verified
REF:PDB:5B73:primary
2016
ZMYND8 Reads the Dual Histone Mark H3K4me1-H3K14ac to Antagonize the Expression of Metastasis-Linked Genes
Mol.Cell
10.1016/j.molcel.2016.06.035
PDB citation metadata; original paper not independently reviewed unless curated record is linked
PMID:26067205
2015
The First Residue of the PWWP Motif Modulates HATH Domain Binding, Stability, and Protein-Protein Interaction.
Biochemistry
10.1021/acs.biochem.5b00454
bibliographic_metadata_and_abstract_verified
PMID:25104842
2014
A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions.
Molecular & cellular proteomics : MCP
10.1074/mcp.m114.038224
bibliographic_metadata_and_abstract_verified
PMID:25263594
2014
BS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processing.
Molecular cell
10.1016/j.molcel.2014.08.022
bibliographic_metadata_and_abstract_verified
PMID:24675531
2014
Crystal structure of human BS69 Bromo-ZnF-PWWP reveals its role in H3K36me3 nucleosome binding.
Cell research
10.1038/cr.2014.38
bibliographic_metadata_and_abstract_verified
PMID:25277115
2014
Structure and function of the nucleosome-binding PWWP domain.
Trends in biochemical sciences
10.1016/j.tibs.2014.09.001
bibliographic_metadata_and_abstract_verified
PMID:24590075
2014
ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.
Nature
10.1038/nature13045
bibliographic_metadata_and_abstract_verified
PMID:23656834
2013
Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain.
Epigenetics & chromatin
10.1186/1756-8935-6-12
primary_full_text_sections_verified
PMID:23396443
2013
Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes.
Nucleic acids research
10.1093/nar/gkt074
primary_full_text_sections_verified
PMID:24312278
2013
TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication.
PloS one
10.1371/journal.pone.0081217
full_text_retrieved_metadata_verified_claims_pending
PMID:23622243
2013
The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα.
Cell
10.1016/j.cell.2013.03.025
bibliographic_metadata_and_abstract_verified
PMID:22734652
2012
Evolution of the PWWP-domain encoding genes in the plant and animal lineages.
BMC evolutionary biology
10.1186/1471-2148-12-101
full_text_retrieved_metadata_verified_claims_pending
PMID:22150589
2012
Solution structure of the Pdp1 PWWP domain reveals its unique binding sites for methylated H4K20 and DNA.
The Biochemical journal
10.1042/bj20111885
bibliographic_metadata_and_abstract_verified
PMID:22247551
2012
Structural insight into recognition of methylated histone tails by retinoblastoma-binding protein 1.
The Journal of biological chemistry
10.1074/jbc.m111.299149
primary_abstract_and_structural_metadata_verified
PMID:21720545
2011
Structural and histone binding ability characterizations of human PWWP domains.
PloS one
10.1371/journal.pone.0018919
primary_full_text_sections_verified
PMID:20400950
2010
Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1.
Nature structural & molecular biology
10.1038/nsmb.1797
bibliographic_metadata_and_abstract_verified
PMID:20347427
2010
Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1.
Molecular cell
10.1016/j.molcel.2009.12.040
bibliographic_metadata_and_abstract_verified
PMID:20547484
2010
The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation.
The Journal of biological chemistry
10.1074/jbc.m109.089433
bibliographic_metadata_and_abstract_verified
PMID:19250904
2009
Regulation of Set9-mediated H4K20 methylation by a PWWP domain protein.
Molecular cell
10.1016/j.molcel.2009.02.002
bibliographic_metadata_and_abstract_verified
PMID:18484749
2008
Human mismatch repair protein MSH6 contains a PWWP domain that targets double stranded DNA.
Biochemistry
10.1021/bi7024639
bibliographic_metadata_and_abstract_verified
PMID:18799576
2008
Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity.
Journal of virology
10.1128/jvi.01561-08
bibliographic_metadata_and_abstract_verified
PMID:17974029
2007
Hepatoma-derived growth factor binds DNA through the N-terminal PWWP domain.
BMC molecular biology
10.1186/1471-2199-8-101
full_text_retrieved_metadata_verified_claims_pending
PMID:17270212
2007
PWWP module of human hepatoma-derived growth factor forms a domain-swapped dimer with much higher affinity for heparin.
Journal of molecular biology
10.1016/j.jmb.2007.01.010
bibliographic_metadata_and_abstract_verified
PMID:16384999
2006
High resolution structure of the HDGF PWWP domain: a potential DNA binding domain.
Protein science : a publication of the Protein Society
10.1110/ps.051751706
bibliographic_metadata_and_abstract_verified
PMID:15689505
2005
Solution structure of the PWWP domain of the hepatoma-derived growth factor family.
Protein science : a publication of the Protein Society
10.1110/ps.04975305
bibliographic_metadata_and_abstract_verified
PMID:14998998
2004
Chromatin targeting of de novo DNA methyltransferases by the PWWP domain.
The Journal of biological chemistry
10.1074/jbc.m312296200
bibliographic_metadata_and_abstract_verified
PMID:15491618
2004
Solution structure and heparin interaction of human hepatoma-derived growth factor.
Journal of molecular biology
10.1016/j.jmb.2004.09.014
bibliographic_metadata_and_abstract_verified
PMID:15456878
2004
The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin.
Molecular and cellular biology
10.1128/mcb.24.20.9048-9058.2004
bibliographic_metadata_and_abstract_verified
PMID:12842472
2003
Structural variation in PWWP domains.
Journal of molecular biology
10.1016/s0022-2836(03)00470-4
bibliographic_metadata_and_abstract_verified
PMID:11836534
2002
The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds.
Nature structural biology
10.1038/nsb759
bibliographic_metadata_and_abstract_verified
PMID:10802047
2000
The PWWP domain: a potential protein-protein interaction domain in nuclear proteins influencing differentiation?
FEBS letters
10.1016/s0014-5793(00)01449-6
bibliographic_metadata_and_abstract_verified
REF:PDB:9T2F:primary
Date uncurated
A fast, parallel method for efficiently exploring crystallization behaviour of large numbers of protein variants
To Be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:9T2G:primary
Date uncurated
A fast, parallel method for efficiently exploring crystallization behaviour of large numbers of protein variants
To Be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:3FLG:primary
Date uncurated
Crystal Structure of the PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 beta
To be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:4Z02:primary
Date uncurated
Crystal structure of BRD1 incomplex with Isoquinoline-3-carboxylic acid
to be published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:4LD6:primary
Date uncurated
Crystal structure of PWWP domain of human PWWP Domain-Containing Protein 2B
To be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:7V8N:primary
Date uncurated
Crystal structure of the PWWP-ARID of ARID4A
To Be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:7LMT:primary
Date uncurated
Histone-lysine N-methyltransferase NSD2-PWWP1 with compound MRT10241866a
To Be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:5C6S:primary
Date uncurated
Human Bromodomain and PHD Finger Containing 1, PWWP domain in complex with XST005904a
to be published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:6KCU:primary
Date uncurated
Shuguo PWWP domain
To Be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:6KD6:primary
Date uncurated
Shuguo PWWP domain
To Be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:6KCO:primary
Date uncurated
Shuguo PWWP in complex with ssDNA
To Be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:6KCP:primary
Date uncurated
Shuguo PWWP in complex with ssDNA
To Be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:2NAS:primary
Date uncurated
Soluion Structure of a PWWP domain from Trypanosoma brucei
To be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:2DAQ:primary
Date uncurated
Solution structure of second PWWP domain of WHSC1L1 protein
To be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:2YRV:primary
Date uncurated
Solution structure of the RBB1NT domain of human RB(retinoblastoma)-binding protein 1
To be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:5XSK:primary
Date uncurated
Structure of PWWP-DNA complex at 2.84 Angstroms resolution
To Be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:5XSL:primary
Date uncurated
Structure of the PWWP domain at 3.3 Angstroms resolution
To Be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:5NR3:primary
Date uncurated
Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors
To be published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:5NRR:primary
Date uncurated
Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors
To be published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:5NRS:primary
Date uncurated
Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors
To be published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:5NRV:primary
Date uncurated
Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors
To be published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:5NV0:primary
Date uncurated
Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors
To Be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:5NV2:primary
Date uncurated
Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors
To Be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:5NV7:primary
Date uncurated
Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors
To be published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:5NVO:primary
Date uncurated
Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors
To be published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:6R3E:primary
Date uncurated
Targeting PWWP domain of DNMT3B for epigenetic cancer therapy: identification and structural characterization of potential protein-protein interaction inhibitors
To be published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:2GFU:primary
Date uncurated
The PWWP domain of Mismatch Repair protein hMSH6 is involved in double stranded and single stranded DNA binding
To be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:9E3U:primary
Date uncurated
The structural basis for de novo DNA methylation in chromatin
To Be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked
REF:PDB:6OQM:primary
Date uncurated
crystal structure of the MSH6 PWWP domain
To Be Published
PDB citation metadata; original paper not independently reviewed unless curated record is linked