STRUCTURAL BIOLOGY & CHEMICAL EVIDENCEDataset v1.2 · Phase 6D · Comparative experimental recognition environments

small molecule preparation

UNC6934

Published observations for this preparation and the reported assay constructs.

exact single CCD identity

Identity scope

Measured preparation

Preparation ID
PREP:UNC6934
Exact CCD identity
V01
Modeled candidate components
None

Assay evidence

Published observations

6 records
Assay recordTarget and constructEndpointReported resultSource
PWWP:ASSAY:0004NSD2 PWWP1
Construct 208–368
SPR Kd= 91.0 nM ± 8.0PMID:34782742
Conditions and interpretation
PWWP:ASSAY:0005NSD2 PWWP1
Construct 208–368
AlphaScreen IC50= 104.0 nM ± 13.0PMID:34782742
Conditions and interpretation
PWWP:ASSAY:0006NSD2 PWWP1
Construct Uncurated–Uncurated
NanoBRET PPI half-response= 1.23 µM ± 0.25PMID:34782742
Conditions and interpretation
PWWP:ASSAY:0014NSD2 PWWP1
Construct 208–368
SPR Kd= 0.24 µM ± 0.03
SD
PMID:40959233
Conditions and interpretation
PWWP:ASSAY:0021NSD2 PWWP1
Construct 211–350
SPR Kd= 1.33 µM ± 0.19
SD
PMID:40959233
Conditions and interpretation
PWWP11:ASSAY:0001NSD3 PWWP1
Construct 263–398
SPR Kd counter-screen> 30.0 µMPMID:40959233
Conditions and interpretation