Studied + deposited research ligandReported probe
BI-9321
NSD3
SPR Kd= 166 ± 3 nMOne source observation · PMID:31285596
3 matching observations1 PWWP research-ligand PDB entries
Scientific evidence classification · Phase 6A preserved + Phase 6B additions
PWWP Compounds
& Bioactivity
Explore experimentally studied preparations separately from deposited research ligands, buffers, ions and unresolved chemical evidence. Every role is source- and target-context specific.
Different denominators · 26 October 2026
38studied preparation profiles · 26 baseline + 12 new
109profiles with PWWP research-ligand geometry
93source assay / association observations · 80 baseline + 13 new
Combined Phase 6A + Phase 6B denominators. These groups overlap; the 109 structurally source-tagged research ligands are unchanged. Deposited components and reagents are not automatically biochemical binders.
Evidence classification · exact source records
7 matching profiles
9 matching assay / association observations. Counts here are profiles, not unique assay events or deposited ligand instances; views overlap.
Identity, assays & sources
Experimental preparationIdentity not assigned
Measurements remain attached to the reported preparation.
Studied · no deposited PWWP research ligand
compound 11 (Collie 2025)
NSD2NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
1 matching observations0 PWWP research-ligand PDB entries
Unresolved preparation · individual modeled components do not inherit its potency.
Experimental preparationIdentity not assigned
Measurements remain attached to the reported preparation.
Studied · no deposited PWWP research ligand
compound 12 (Collie 2025)
NSD2NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
1 matching observations0 PWWP research-ligand PDB entries
Unresolved preparation · individual modeled components do not inherit its potency.
Experimental preparationIdentity not assigned
Measurements remain attached to the reported preparation.
Studied · no deposited PWWP research ligand
compound 13 (Collie 2025)
NSD2NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
1 matching observations0 PWWP research-ligand PDB entries
Unresolved preparation · individual modeled components do not inherit its potency.
Experimental preparationIdentity not assigned
Measurements remain attached to the reported preparation.
Studied · no deposited PWWP research ligand
compound 5 (Collie 2025)
NSD2NSD3
SPR Kd counter-screen> 30 µMOne source observation · PMID:40959233
1 matching observations0 PWWP research-ligand PDB entries
Unresolved preparation · individual modeled components do not inherit its potency.
Experimental preparationIdentity not assigned
Measurements remain attached to the reported preparation.
Studied · no deposited PWWP research ligand
compound 6 (Collie 2025)
NSD2NSD3
SPR Kd counter-screen> 30 µMOne source observation · PMID:40959233
1 matching observations0 PWWP research-ligand PDB entries
Unresolved preparation · individual modeled components do not inherit its potency.
Experimental preparationIdentity not assigned
Measurements remain attached to the reported preparation.
Studied · no deposited PWWP research ligandExperiment-specific control
MS9715N
NSD3
ITC Kd= 1.62 ± 0.33 µMOne source observation · PMID:34469831
1 matching observations0 PWWP research-ligand PDB entries
Unresolved preparation · individual modeled components do not inherit its potency.