Studied + deposited research ligandReported probe
BI-9321
NSD3
SPR Kd= 166 ± 3 nMOne source observation · PMID:31285596
3 matching observations1 PWWP research-ligand PDB entries
Scientific evidence classification · Phase 6A preserved + Phase 6B additions
PWWP Compounds
& Bioactivity
Explore experimentally studied preparations separately from deposited research ligands, buffers, ions and unresolved chemical evidence. Every role is source- and target-context specific.
Different denominators · 26 October 2026
38studied preparation profiles · 26 baseline + 12 new
109profiles with PWWP research-ligand geometry
93source assay / association observations · 80 baseline + 13 new
Combined Phase 6A + Phase 6B denominators. These groups overlap; the 109 structurally source-tagged research ligands are unchanged. Deposited components and reagents are not automatically biochemical binders.
Evidence classification · exact source records
19 matching profiles
13 matching assay / association observations. Counts here are profiles, not unique assay events or deposited ligand instances; views overlap.
Identity, assays & sources
Studied · no deposited PWWP research ligandExperiment-specific control
BI-9466
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
1 matching observations0 PWWP research-ligand PDB entries
Experimental preparationIdentity not assigned
Measurements remain attached to the reported preparation.
Studied · no deposited PWWP research ligand
compound 11 (Collie 2025)
NSD2NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
1 matching observations0 PWWP research-ligand PDB entries
Unresolved preparation · individual modeled components do not inherit its potency.
Experimental preparationIdentity not assigned
Measurements remain attached to the reported preparation.
Studied · no deposited PWWP research ligand
compound 12 (Collie 2025)
NSD2NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
1 matching observations0 PWWP research-ligand PDB entries
Unresolved preparation · individual modeled components do not inherit its potency.
Experimental preparationIdentity not assigned
Measurements remain attached to the reported preparation.
Studied · no deposited PWWP research ligand
compound 13 (Collie 2025)
NSD2NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
1 matching observations0 PWWP research-ligand PDB entries
Unresolved preparation · individual modeled components do not inherit its potency.
Experimental preparationIdentity not assigned
Measurements remain attached to the reported preparation.
Studied · no deposited PWWP research ligand
compound 5 (Collie 2025)
NSD2NSD3
SPR Kd counter-screen> 30 µMOne source observation · PMID:40959233
1 matching observations0 PWWP research-ligand PDB entries
Unresolved preparation · individual modeled components do not inherit its potency.
Experimental preparationIdentity not assigned
Measurements remain attached to the reported preparation.
Studied · no deposited PWWP research ligand
compound 6 (Collie 2025)
NSD2NSD3
SPR Kd counter-screen> 30 µMOne source observation · PMID:40959233
1 matching observations0 PWWP research-ligand PDB entries
Unresolved preparation · individual modeled components do not inherit its potency.
Studied · no deposited PWWP research ligand
compound 7 (Collie 2025)
NSD2NSD3
SPR Kd counter-screen> 30 µMOne source observation · PMID:40959233
1 matching observations0 PWWP research-ligand PDB entries
Studied · no deposited PWWP research ligand
MS9715
NSD3
ITC Kd= 1.3 ± 0.17 µMOne source observation · PMID:34469831
1 matching observations0 PWWP research-ligand PDB entries
Experimental preparationIdentity not assigned
Measurements remain attached to the reported preparation.
Studied · no deposited PWWP research ligandExperiment-specific control
MS9715N
NSD3
ITC Kd= 1.62 ± 0.33 µMOne source observation · PMID:34469831
1 matching observations0 PWWP research-ligand PDB entries
Unresolved preparation · individual modeled components do not inherit its potency.
Studied · no deposited PWWP research ligand
UNC6934
NSD2NSD3
SPR Kd counter-screen> 30 µMOne source observation · PMID:40959233
1 matching observations0 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 2-[(~{E})-2-thiophen-2-ylethenyl]benzoic acid](/compounds/depiction/2ea4c42c778a41e7a970-light.svg)
![Verified 2D molecular structure of 2-[(~{E})-2-thiophen-2-ylethenyl]benzoic acid](/compounds/depiction/2ea4c42c778a41e7a970-dark.svg)
Deposited research ligand · no curated assay
2-[(~{E})-2-thiophen-2-ylethenyl]benzoic acid
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)-1,2-oxazole
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
3,5-dimethyl-4-(4-pyridin-4-yl-1~{H}-pyrazol-3-yl)-1,2-oxazole
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
4-(3-methyl-5-phenyl-imidazol-4-yl)pyridine
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of 4-[5-(7-fluoranylquinolin-4-yl)-1-methyl-imidazol-4-yl]-3,5-dimethyl-1,2-oxazole](/compounds/depiction/a777f153aedb74c06a50-light.svg)
![Verified 2D molecular structure of 4-[5-(7-fluoranylquinolin-4-yl)-1-methyl-imidazol-4-yl]-3,5-dimethyl-1,2-oxazole](/compounds/depiction/a777f153aedb74c06a50-dark.svg)
Deposited research ligand · no curated assay
4-[5-(7-fluoranylquinolin-4-yl)-1-methyl-imidazol-4-yl]-3,5-dimethyl-1,2-oxazole
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
5-methyl-2-piperidin-4-yl-6-pyridin-4-yl-pyridazin-3-one
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
Deposited research ligand · no curated assay
5-methyl-6-phenyl-2-piperidin-4-yl-pyridazin-3-one
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries
![Verified 2D molecular structure of [3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)phenyl]methanamine](/compounds/depiction/feba6300aa726bcedcc9-light.svg)
![Verified 2D molecular structure of [3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)phenyl]methanamine](/compounds/depiction/feba6300aa726bcedcc9-dark.svg)
Deposited research ligand · no curated assay
[3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)phenyl]methanamine
NSD3
No source-curated measured assay in this context. Structural evidence is shown separately.
0 matching observations1 PWWP research-ligand PDB entries