PWWPAtlas
STRUCTURAL BIOLOGY & CHEMICAL EVIDENCEDataset v1.2 · Phase 6D · Comparative experimental recognition environments

Scientific evidence classification · Phase 6A preserved + Phase 6B additions

PWWP Compounds
& Bioactivity

Explore experimentally studied preparations separately from deposited research ligands, buffers, ions and unresolved chemical evidence. Every role is source- and target-context specific.

Explore studied compoundsStructural & Binding Landscape →
Different denominators · 26 October 2026
38studied preparation profiles · 26 baseline + 12 new
109profiles with PWWP research-ligand geometry
93source assay / association observations · 80 baseline + 13 new

Combined Phase 6A + Phase 6B denominators. These groups overlap; the 109 structurally source-tagged research ligands are unchanged. Deposited components and reagents are not automatically biochemical binders.

Assay, source & experimental-context filters

Assay filters must match the same observation. Concentration ranges require one endpoint and exact positive measurements; inequalities and qualitative findings remain searchable separately.

Reset filtersProtein-level observations are never copied to individual PWWP domains.

Phase 6B · source-reviewed additions (separate from the Phase 6A snapshot)

0 matching new observations · 0 preparations

Keep source-level IC50, Kd, and whole-protein DC50 separate; these records were not included in the original 80.

Filter all Phase 6B assay contexts
PreparationTarget scopeOriginal assayPrimary source
No Phase 6B additions match the selected observation-level filters. This does not erase existing Phase 6A observations.

Evidence classification · exact source records

11 matching profiles

13 matching assay / association observations. Counts here are profiles, not unique assay events or deposited ligand instances; views overlap.

Export assay CSVExport evidence JSON
Verified 2D molecular structure of BI-9321 Verified 2D molecular structure of BI-9321
Studied + deposited research ligandReported probe

BI-9321

NSD3
SPR Kd= 166 ± 3 nMOne source observation · PMID:31285596
3 matching observations1 PWWP research-ligand PDB entries
Identity, assays & sources
Verified 2D molecular structure of BI-9466 Verified 2D molecular structure of BI-9466
Studied · no deposited PWWP research ligandExperiment-specific control

BI-9466

NSD3

No source-curated measured assay in this context. Structural evidence is shown separately.

1 matching observations0 PWWP research-ligand PDB entries
Identity, assays & sources
Verified 2D molecular structure of MS9715 Verified 2D molecular structure of MS9715
Studied · no deposited PWWP research ligand

MS9715

NSD3
ITC Kd= 1.3 ± 0.17 µMOne source observation · PMID:34469831
1 matching observations0 PWWP research-ligand PDB entries
Identity, assays & sources
Verified 2D molecular structure of UNC6934 Verified 2D molecular structure of UNC6934
Studied · no deposited PWWP research ligand

UNC6934

NSD2NSD3
SPR Kd counter-screen> 30 µMOne source observation · PMID:40959233
1 matching observations0 PWWP research-ligand PDB entries
Identity, assays & sources