Phase 6B · provenance and decision ledger
Deferred source leads
Source review outcomes are not automatically accepted assays or biological negatives. Original identifiers and frozen evidence remain intact.
6 / 6 records
CSV download (selected status)| Record ID | Source / evidence | Review outcome | Original data & limitations |
|---|---|---|---|
| P6B:LEAD:92B7_IC50 | 92-B7 (parthenolide) | unpromoted Source-level review pending | Original assay technique and preparation not independently reconciled; no new accepted profile Full source/provenance record{
"endpoint": "IC50",
"lead_id": "P6B:LEAD:92B7_IC50",
"name": "92-B7 (parthenolide)",
"reason": "Original assay technique and preparation not independently reconciled; no new accepted profile",
"relation": "=",
"source_id": "P6B:S:HS132026",
"source_location": "Publisher abstract",
"target": "NSD2 PWWP1",
"units": "\u00b5M",
"value": 332
} |
| P6B:LEAD:HS13_IC50 | HS13 | unpromoted Source-level review pending | Assay system, construct, and exact chemistry not independently extracted Full source/provenance record{
"endpoint": "IC50",
"lead_id": "P6B:LEAD:HS13_IC50",
"name": "HS13",
"original_observation_id": "PWWP:ASSAY:0035",
"reason": "Assay system, construct, and exact chemistry not independently extracted",
"relation": "=",
"source_id": "P6B:S:HS132026",
"source_location": "Publisher Results preview",
"target": "NSD2 PWWP1",
"units": "\u00b5M",
"value": 21.62
} |
| P6B:LEAD:HS13_KD | HS13 | unpromoted Source-level review pending | Existing qualitative record, exact assay method and chemical preparation remain unresolved; quantitative value kept as source-reported lead, not counted anew Full source/provenance record{
"endpoint": "Kd",
"lead_id": "P6B:LEAD:HS13_KD",
"name": "HS13",
"original_observation_id": "PWWP:ASSAY:0035",
"reason": "Existing qualitative record, exact assay method and chemical preparation remain unresolved; quantitative value kept as source-reported lead, not counted anew",
"relation": "=",
"source_id": "P6B:S:HS132026",
"source_location": "Abstract",
"target": "NSD2 PWWP1",
"units": "\u00b5M",
"value": 8.33
} |
| P6B:LEAD:LY06_KD | LY-06 | unpromoted Source-level review pending | Published source abstract supports claim; original assay/structure and full chemical identity not independently reconciled Full source/provenance record{
"endpoint": "Kd",
"lead_id": "P6B:LEAD:LY06_KD",
"name": "LY-06",
"reason": "Published source abstract supports claim; original assay/structure and full chemical identity not independently reconciled",
"relation": "=",
"source_id": "P6B:S:LY2026",
"source_location": "Publisher abstract",
"target": "NSD3 PWWP1",
"uncertainty": 0.05,
"units": "\u00b5M",
"value": 1.69
} |
| P6B:LEAD:XSY12_DC50 | XSY12 | unpromoted Source-level review pending | Cellular degradation only; exact assayed preparation and full method not independently extracted Full source/provenance record{
"endpoint": "DC50",
"lead_id": "P6B:LEAD:XSY12_DC50",
"name": "XSY12",
"reason": "Cellular degradation only; exact assayed preparation and full method not independently extracted",
"relation": "=",
"source_id": "P6B:S:XIU2026",
"source_location": "Publisher abstract",
"target": "cellular NSD3 protein",
"units": "\u00b5M",
"value": 2.21
} |
| P6B:LEAD:XSY12_DMAX | XSY12 | unpromoted Source-level review pending | Protein-level degradation magnitude; not an affinity Full source/provenance record{
"endpoint": "Dmax",
"lead_id": "P6B:LEAD:XSY12_DMAX",
"name": "XSY12",
"reason": "Protein-level degradation magnitude; not an affinity",
"relation": "=",
"source_id": "P6B:S:XIU2026",
"source_location": "Publisher abstract",
"target": "cellular NSD3 protein",
"units": "%",
"value": 80.2
} |