STRUCTURAL BIOLOGY & CHEMICAL EVIDENCEDataset v1.2 · Phase 6D · Comparative experimental recognition environments

small molecule preparation

compound 12 (Collie 2025)

Published observations for this preparation and the reported assay constructs.

paper label exact identity unresolved

Identity scope

Measured preparation

Preparation ID
PREP:COLLIE2025_12
Exact CCD identity
Unresolved at exact-identity level
Modeled candidate components
None

Assay evidence

Published observations

4 records
Assay recordTarget and constructEndpointReported resultSource
PWWP:ASSAY:0019NSD2 PWWP1
Construct 208–368
SPR Kd= 1.47 µM ± 0.13
SD
PMID:40959233
Conditions and interpretation
PWWP:ASSAY:0026NSD2 PWWP1
Construct 211–350
SPR Kd= 2.8 µM ± 0.31
SD
PMID:40959233
Conditions and interpretation
PWWP:ASSAY:0030NSD2 PWWP1
Construct 208–368
HTRF displacement IC50= 2.49 µM ± 0.06
SEM
PMID:40959233
Conditions and interpretation
PWWP11:ASSAY:0006NSD3 PWWP1
Construct 263–398
SPR Kd counter-screenNo bindingPMID:40959233
Conditions and interpretation