Evidence explorer

Structure and assay evidence

Follow DNMT3A from a deposited contact to its preparation, assay and primary source.

Complete query JSON

6exact contact–assay rows

0assay rows without an exact contact link

1preparation records

DNMT3A · Structure-linked observations

Exact identity links to deposited contacts

6 rows

6 rows join a geometric contact to an assay on the same native target/domain. Multiple rows may describe the same ligand, structure or measurement. Chain-contact rank is geometric and is not a biological-site assignment.

PDB and chain	Domain / component	Contact evidence	Preparation and measurement	Assay construct and source
3LLR Chain A	PWWP1 · BTB INCHIKEY:OWMVSZAMULFTJU-UHFFFAOYSA-N	native annotation core contact Core 2.68 Å Broader 2.68 Å Distance rank 1	Bis-Tris No pharmacological activity assigned No numeric activity assigned Preparation identity	Uncurated boundaries Primary evidence Pocket occupancy in high-concentration crystallization buffer is not evidence of potency. Link interpretation same exact chemical identity and native domain; construct equivalence not assumed
3LLR Chain B	PWWP1 · BTB INCHIKEY:OWMVSZAMULFTJU-UHFFFAOYSA-N	native annotation core contact Core 2.56 Å Broader 2.56 Å Distance rank 1	Bis-Tris No pharmacological activity assigned No numeric activity assigned Preparation identity	Uncurated boundaries Primary evidence Pocket occupancy in high-concentration crystallization buffer is not evidence of potency. Link interpretation same exact chemical identity and native domain; construct equivalence not assumed
3LLR Chain C	PWWP1 · BTB INCHIKEY:OWMVSZAMULFTJU-UHFFFAOYSA-N	native annotation core contact Core 2.41 Å Broader 2.41 Å Distance rank 1; multiple chains contact this component	Bis-Tris No pharmacological activity assigned No numeric activity assigned Preparation identity	Uncurated boundaries Primary evidence Pocket occupancy in high-concentration crystallization buffer is not evidence of potency. Link interpretation same exact chemical identity and native domain; construct equivalence not assumed
3LLR Chain E	PWWP1 · BTB INCHIKEY:OWMVSZAMULFTJU-UHFFFAOYSA-N	isolated construct contact outside annotations Core 9.65 Å Broader 9.65 Å Distance rank 2; multiple chains contact this component	Bis-Tris No pharmacological activity assigned No numeric activity assigned Preparation identity	Uncurated boundaries Primary evidence Pocket occupancy in high-concentration crystallization buffer is not evidence of potency. Link interpretation same exact chemical identity and native domain; construct equivalence not assumed
3LLR Chain D	PWWP1 · BTB INCHIKEY:OWMVSZAMULFTJU-UHFFFAOYSA-N	native annotation core contact Core 2.62 Å Broader 2.62 Å Distance rank 1	Bis-Tris No pharmacological activity assigned No numeric activity assigned Preparation identity	Uncurated boundaries Primary evidence Pocket occupancy in high-concentration crystallization buffer is not evidence of potency. Link interpretation same exact chemical identity and native domain; construct equivalence not assumed
3LLR Chain E	PWWP1 · BTB INCHIKEY:OWMVSZAMULFTJU-UHFFFAOYSA-N	native annotation core contact Core 2.64 Å Broader 2.64 Å Distance rank 1	Bis-Tris No pharmacological activity assigned No numeric activity assigned Preparation identity	Uncurated boundaries Primary evidence Pocket occupancy in high-concentration crystallization buffer is not evidence of potency. Link interpretation same exact chemical identity and native domain; construct equivalence not assumed

DNMT3A · Additional published evidence

Assays without an exact contact link

0 records

These observations remain usable at their stated preparation and assay level. A negative result, missing co-crystal, unresolved preparation or mixed stereochemistry can prevent an exact contact link.

Preparation	Result	Identity status	Source
No additional assay-only row.

DNMT3A · Identity scope

Preparation identities and modeled candidates

1 records

Preparation	Identity status	Exact identity	Modeled candidates
Bis-Tris	exact single CCD identity	INCHIKEY:OWMVSZAMULFTJU-UHFFFAOYSA-N	[] Complete deposited identity retained; no connectivity-only or name-only merge.