Experimental structure
3LLR
Crystal structure of the PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 alpha
Original coordinates
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Coordinate coverage
Mapped chains
Label and author chain identifiers are kept separately. Observed Cα counts refer to each mapped annotation core.
| Protein | Label chain | Author chain | Domain | Observed Cα / core | Observed substitutions |
|---|---|---|---|---|---|
| DNMT3A | A | ["A"] | UP:Q9Y6K1:PWWP1 | 59 / 59 | 0 |
| DNMT3A | B | ["B"] | UP:Q9Y6K1:PWWP1 | 59 / 59 | 0 |
| DNMT3A | C | ["C"] | UP:Q9Y6K1:PWWP1 | 59 / 59 | 0 |
| DNMT3A | D | ["D"] | UP:Q9Y6K1:PWWP1 | 59 / 59 | 0 |
| DNMT3A | E | ["E"] | UP:Q9Y6K1:PWWP1 | 59 / 59 | 0 |
Chemical identity
Chemical components and interpretation
Geometry, with defined scope
Independent contact evidence
Inspect 7 retained contact records
| CCD / instance | Protein chain | Contact class | Minimum core / broader domain distance Å |
|---|---|---|---|
| BTB · F | DNMT3A · A | native annotation core contact | 2.68 / 2.68 |
| BTB · G | DNMT3A · B | native annotation core contact | 2.56 / 2.56 |
| BTB · I | DNMT3A · C | native annotation core contact | 2.41 / 2.41 |
| BTB · J | DNMT3A · D | native annotation core contact | 2.62 / 2.62 |
| BTB · I | DNMT3A · E | isolated construct contact outside annotations | 9.65 / 9.65 |
| BTB · K | DNMT3A · E | native annotation core contact | 2.64 / 2.64 |
| SO4 · H | DNMT3A · B | native annotation core contact | 3.1 / 3.1 |
Biological partners
No curated macromolecular partner record.
Source interpretation
Focused scientific audit
retain with stated interpretation/caveats. APO is justified under the declared functional-ligand definition: nearby BTB and sulfate are buffer/additive species. APO does not mean absence of all heteroatoms.