STRUCTURAL BIOLOGY & CHEMICAL EVIDENCEDataset v1.2 · Phase 6D · Comparative experimental recognition environments

Published assay observation

Bis-Tris and DNMT3A

PWWP:ASSAY:0033

structural occupancy association

Reported observation

No pharmacological activity assigned

No verified numeric result

Target domain
UP:Q9Y6K1:PWWP1
Assay construct
Uncurated–Uncurated
Identity scope
exact single CCD identity

Evidence provenance

Primary source

PMID:21720545

Results: Trimethylated lysine histone recognition; crystallization methods

Verification scope
local_primary_full_text_XML; Tables 1-2, crystallization methods and ligand Results inspected
Assay and verification JSON

Field-level provenance

Assay conditions and source verification

Missing information is not proof of absence. The v1.2 source overlay separates not reported in inspected material, not inspected, not transcribed and not applicable.

buffer
Crystallization reservoir contains 0.1 M Bis-Tris; not an affinity assay
pH
6.0
DMSO percent
Uncurated; field-level source review not performed for this record
temperature C
Uncurated; field-level source review not performed for this record
replicates
Uncurated; field-level source review not performed for this record
uncertainty type
Uncurated; field-level source review not performed for this record

Structure → Component → Assay

Exact identity contact links

6 contact links

3LLR BTB

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

3LLR BTB

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

3LLR BTB

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

3LLR BTB

isolated construct contact outside annotations

same exact chemical identity and native domain; construct equivalence not assumed

3LLR BTB

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

3LLR BTB

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed