Resolved chemical identity

GLYCEROL

Other PDB component · not a studied ligand

complete_deposited_InChIKey

O75475 PWWP1 O96028 PWWP1 Q6NUJ5 PWWP1 Q7Z4V5 PWWP1 Q9UBC3 PWWP1

0 assay / association records0 preparations0 research-ligand PDB entries

No deposited PWWP research-ligand geometry is classified for this preparation in the selected release. Deposition of a buffer/ion is not binding evidence.

Clinical / development status: Not independently curated. A chemical probe classification does not imply medicinal approval.

Identity is separate from preparation

Chemical identity

Stable identity: INCHIKEY:PEDCQBHIVMGVHV-UHFFFAOYSA-N
Full InChIKey: PEDCQBHIVMGVHV-UHFFFAOYSA-N
Source identity status: complete deposited InChIKey
Deposited CCD identifiers: GOL
External identifiers: See deposited identity and source links

Reference formula: C3H8O3
Calculated molecular weight: 92.094
Calculated descriptors: cLogP -1.6681 · TPSA 60.69 Å² · HBD 3 · HBA 3RDKit 2025.09.3; calculations for this source identity, not experimental measurements.
Depiction validation: verified smiles full inchikey match

SMILES, InChI & complete identity record

Isomeric SMILES: C(C(CO)O)O
InChI: Not curated

{
  "aliases": [
    "GLYCEROL"
  ],
  "ccd_ids": [
    "GOL"
  ],
  "ccd_names": "[\"GLYCEROL\"]",
  "ccd_types": "[\"non-polymer\"]",
  "chemical_id": "INCHIKEY:PEDCQBHIVMGVHV-UHFFFAOYSA-N",
  "connectivity_block": "PEDCQBHIVMGVHV",
  "curated_source_sha256": null,
  "curation_version": "frozen-v1.2",
  "external_identifiers": {},
  "formal_charge_by_ccd": "{\"GOL\": 0}",
  "formulae": "[\"C3 H8 O3\"]",
  "geometry_note": "CCD ideal SDF is a reference chemical geometry, not a deposited bound pose.",
  "identity_status": "complete_deposited_InChIKey",
  "inchikey": "PEDCQBHIVMGVHV-UHFFFAOYSA-N",
  "inventory_origin": "v1_CCD_inventory",
  "isomeric_smiles": "C(C(CO)O)O",
  "primary_name": "GLYCEROL",
  "retrieval_date": "2026-10-24",
  "smiles_stereo_by_ccd": "{\"GOL\": \"C(C(CO)O)O\"}",
  "source_metadata_sha256": "{\"GOL\": \"66aeba7585a9ac47748bba1ce40011f52f7cb5769eb6984f7e380d477e47dd17\"}",
  "source_urls": [
    "https://www.rcsb.org/ligand/GOL"
  ]
}

Measured target and original context

Bioactivity & experimental observations

Download assay CSV

Each row is one source-specific observation. Repeated measurements of this compound are not independent compounds. Direct binding, functional displacement and cellular outcomes retain their distinct endpoints.

Preparation	Tested target & construct	Method / endpoint	Original observation	Conditions & uncertainty	Source & verification
No observations match these filters. Missing curation is not evidence of biological inactivity.

Exact deposited instances

Experimental structures

Native-core and broader Pfam proximity are distinguished from contacts elsewhere in a protein. Each action opens the actual deposited ligand instance. Geometric proximity does not supply a measured binding affinity.

Entry / ligand	Native domain & protein chain	Geometric evidence	Minimum distance	Inspect
4FU6 · GOLPDB:4FU6:LIG:E:GOL:204:.	PSIP1 PWWP1Protein label chain A · ligand label chain E	native annotation core contactcryoprotectant/additivecryoprotectant · other component. Deposited geometry is not solution affinity.	Core: 2.4323 Å Pfam: 2.4323 Å	View deposited instance
4LD6 · GOLPDB:4LD6:LIG:B:GOL:3001:.	PWWP2B PWWP1Protein label chain A · ligand label chain B	native annotation core contactcryoprotectant/additivecryoprotectant · other component. Deposited geometry is not solution affinity.	Core: 2.6227 Å Pfam: 2.6227 Å	View deposited instance
5CIU · GOLPDB:5CIU:LIG:E:GOL:401:.	DNMT3B PWWP1Protein label chain B · ligand label chain E	native annotation core contactcryoprotectant/additivecryoprotectant · other component. Deposited geometry is not solution affinity.	Core: 2.2725 Å Pfam: 2.2725 Å	View deposited instance
5Y1Z · GOLPDB:5Y1Z:LIG:Q:GOL:506:.	ZMYND8 PWWP1Protein label chain C · ligand label chain Q	noncore contact in multidomain chaincryoprotectant/additivecryoprotectant · other component. Deposited geometry is not solution affinity.	Core: 15.1281 Å Pfam: 5.8007 Å	View deposited instance
5Y1Z · GOLPDB:5Y1Z:LIG:Q:GOL:506:.	ZMYND8 PWWP1Protein label chain D · ligand label chain Q	noncore contact in multidomain chaincryoprotectant/additivecryoprotectant · other component. Deposited geometry is not solution affinity.	Core: 35.1251 Å Pfam: 35.1251 Å	View deposited instance
9I7D · GOLPDB:9I7D:LIG:C:GOL:201:.	HDGFL2 PWWP1Protein label chain A · ligand label chain C	native annotation core contactcryoprotectant/additivecryoprotectant · other component. Deposited geometry is not solution affinity.	Core: 3.0647 Å Pfam: 3.0647 Å	View deposited instance
9I7D · GOLPDB:9I7D:LIG:H:GOL:201:.	HDGFL2 PWWP1Protein label chain B · ligand label chain H	native annotation core contactcryoprotectant/additivecryoprotectant · other component. Deposited geometry is not solution affinity.	Core: 2.6142 Å Pfam: 2.6142 Å	View deposited instance
9KNA · GOLPDB:9KNA:LIG:F:GOL:404:.	NSD2 PWWP1Protein label chain A · ligand label chain F	native annotation core contactcryoprotectant/additivecryoprotectant · other component. Deposited geometry is not solution affinity.	Core: 3.4689 Å Pfam: 3.4689 Å	View deposited instance
9KNA · GOLPDB:9KNA:LIG:F:GOL:404:.	NSD2 PWWP1Protein label chain B · ligand label chain F	native annotation core contactcryoprotectant/additivecryoprotectant · other component. Deposited geometry is not solution affinity.	Core: 2.9209 Å Pfam: 2.9209 Å	View deposited instance
9KNA · GOLPDB:9KNA:LIG:K:GOL:403:.	NSD2 PWWP1Protein label chain A · ligand label chain K	native annotation core contactcryoprotectant/additivecryoprotectant · other component. Deposited geometry is not solution affinity.	Core: 3.5362 Å Pfam: 3.5362 Å	View deposited instance
9KNA · GOLPDB:9KNA:LIG:K:GOL:403:.	NSD2 PWWP1Protein label chain B · ligand label chain K	native annotation core contactcryoprotectant/additivecryoprotectant · other component. Deposited geometry is not solution affinity.	Core: 3.2023 Å Pfam: 3.2023 Å	View deposited instance

Preparations, identities and controls remain separate

Experimental context

No measured preparation is linked to this deposited identity in the curated snapshot.

Provenance and reproducibility

Sources & downloads

https://www.rcsb.org/ligand/GOL

Download complete evidence JSON Curation methods & source receipts

Snapshot 2026-10-26 · phase5-1.0.0 · original measurements, operators, constructs and uncertainty are retained in the exports.