STRUCTURAL BIOLOGY & CHEMICAL EVIDENCEDataset v1.2 · Phase 6D · Comparative experimental recognition environments

Experimental structure

5CIU

Structural basis of the recognition of H3K36me3 by DNMT3B PWWP domain

Complexes PWWP coordinates observed X-RAY DIFFRACTION

Original coordinates

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PDB deposition
5CIU Deposited model
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Original coordinates are available from a locally verified historical archive or the bundled source and load on request.

Coordinate coverage

Mapped chains

2 chain / domain rows

Label and author chain identifiers are kept separately. Observed Cα counts refer to each mapped annotation core.

ProteinLabel chainAuthor chainDomainObserved Cα / coreObserved substitutions
DNMT3BA["A"]UP:Q9UBC3:PWWP159 / 590
DNMT3BB["B"]UP:Q9UBC3:PWWP159 / 590

Chemical identity

Chemical components and interpretation

2 component records
CCDNameRoleFull InChIKey
GOLGLYCEROLcryoprotectant/additive
incidental
PEDCQBHIVMGVHV-UHFFFAOYSA-N
HOHWATERsolvent
incidental
XLYOFNOQVPJJNP-UHFFFAOYSA-N

Geometry, with defined scope

Independent contact evidence

Inspect 3 retained contact records
CCD / instanceProtein chainContact classMinimum core / broader domain distance Å
GOL · EDNMT3B · Bnative annotation core contact2.27 / 2.27
M3L · DDNMT3B · Anative annotation core contact2.99 / 2.99
M3L · CDNMT3B · Bnative annotation core contact2.89 / 2.89

Biological partners

Histone H3.2 · histone or histone peptide · label chains ["C","D"]

Source interpretation

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This entry was included in all-entry coordinate/contact calculations but not in the 36-entry focused structural sample.