STRUCTURAL BIOLOGY & CHEMICAL EVIDENCEDataset v1.2 · Phase 6D · Comparative experimental recognition environments

Experimental structure

8EIK

Cryo-EM structure of human DNMT3B homo-hexamer

Unclassified_Review No mapped PWWP coordinates ELECTRON MICROSCOPY

Original coordinates

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PDB deposition
8EIK Deposited model
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Original coordinates are available from a locally verified historical archive or the bundled source and load on request.

Coordinate coverage

Mapped chains

6 chain / domain rows

Label and author chain identifiers are kept separately. Observed Cα counts refer to each mapped annotation core.

ProteinLabel chainAuthor chainDomainObserved Cα / coreObserved substitutions
DNMT3BA["A"]UP:Q9UBC3:PWWP10 / 590
DNMT3BB["B"]UP:Q9UBC3:PWWP10 / 590
DNMT3BC["D"]UP:Q9UBC3:PWWP10 / 590
DNMT3BD["C"]UP:Q9UBC3:PWWP10 / 590
DNMT3BE["E"]UP:Q9UBC3:PWWP10 / 590
DNMT3BF["F"]UP:Q9UBC3:PWWP10 / 590

Chemical identity

Chemical components and interpretation

2 component records
CCDNameRoleFull InChIKey
SAHS-ADENOSYL-L-HOMOCYSTEINEbiological cofactor
functional
ZJUKTBDSGOFHSH-WFMPWKQPSA-N
ZNZINC IONion/cofactor_requires_context
incidental
PTFCDOFLOPIGGS-UHFFFAOYSA-N

Geometry, with defined scope

Independent contact evidence

Inspect 15 retained contact records
CCD / instanceProtein chainContact classMinimum core / broader domain distance Å
SAH · GDNMT3B · Anoncore contact in multidomain chain— / —
SAH · KDNMT3B · Bnoncore contact in multidomain chain— / —
SAH · ODNMT3B · Dnoncore contact in multidomain chain— / —
ZN · HDNMT3B · Anoncore contact in multidomain chain— / —
ZN · IDNMT3B · Anoncore contact in multidomain chain— / —
ZN · JDNMT3B · Anoncore contact in multidomain chain— / —
ZN · LDNMT3B · Bnoncore contact in multidomain chain— / —
ZN · MDNMT3B · Bnoncore contact in multidomain chain— / —
ZN · NDNMT3B · Bnoncore contact in multidomain chain— / —
ZN · PDNMT3B · Dnoncore contact in multidomain chain— / —
ZN · QDNMT3B · Dnoncore contact in multidomain chain— / —
ZN · RDNMT3B · Dnoncore contact in multidomain chain— / —
ZN · SDNMT3B · Enoncore contact in multidomain chain— / —
ZN · TDNMT3B · Enoncore contact in multidomain chain— / —
ZN · UDNMT3B · Enoncore contact in multidomain chain— / —

Biological partners

No curated macromolecular partner record.

Source interpretation

Focused scientific audit

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This entry was included in all-entry coordinate/contact calculations but not in the 36-entry focused structural sample.