STRUCTURAL BIOLOGY & CHEMICAL EVIDENCEDataset v1.2 · Phase 6D · Comparative experimental recognition environments

Experimental structure

8EII

Cryo-EM structure of human DNMT3B homo-tetramer (form II)

Unclassified_Review No mapped PWWP coordinates ELECTRON MICROSCOPY

Original coordinates

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PDB deposition
8EII Deposited model
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Original coordinates are available from a locally verified historical archive or the bundled source and load on request.

Coordinate coverage

Mapped chains

4 chain / domain rows

Label and author chain identifiers are kept separately. Observed Cα counts refer to each mapped annotation core.

ProteinLabel chainAuthor chainDomainObserved Cα / coreObserved substitutions
DNMT3BA["A"]UP:Q9UBC3:PWWP10 / 590
DNMT3BB["B"]UP:Q9UBC3:PWWP10 / 590
DNMT3BC["C"]UP:Q9UBC3:PWWP10 / 590
DNMT3BD["D"]UP:Q9UBC3:PWWP10 / 590

Chemical identity

Chemical components and interpretation

2 component records
CCDNameRoleFull InChIKey
SAHS-ADENOSYL-L-HOMOCYSTEINEbiological cofactor
functional
ZJUKTBDSGOFHSH-WFMPWKQPSA-N
ZNZINC IONion/cofactor_requires_context
incidental
PTFCDOFLOPIGGS-UHFFFAOYSA-N

Geometry, with defined scope

Independent contact evidence

Inspect 11 retained contact records
CCD / instanceProtein chainContact classMinimum core / broader domain distance Å
SAH · EDNMT3B · Anoncore contact in multidomain chain— / —
SAH · IDNMT3B · Bnoncore contact in multidomain chain— / —
ZN · FDNMT3B · Anoncore contact in multidomain chain— / —
ZN · GDNMT3B · Anoncore contact in multidomain chain— / —
ZN · HDNMT3B · Anoncore contact in multidomain chain— / —
ZN · JDNMT3B · Bnoncore contact in multidomain chain— / —
ZN · KDNMT3B · Bnoncore contact in multidomain chain— / —
ZN · LDNMT3B · Bnoncore contact in multidomain chain— / —
ZN · MDNMT3B · Cnoncore contact in multidomain chain— / —
ZN · NDNMT3B · Cnoncore contact in multidomain chain— / —
ZN · ODNMT3B · Cnoncore contact in multidomain chain— / —

Biological partners

No curated macromolecular partner record.

Source interpretation

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This entry was included in all-entry coordinate/contact calculations but not in the 36-entry focused structural sample.