STRUCTURAL BIOLOGY & CHEMICAL EVIDENCEDataset v1.2 · Phase 6D · Comparative experimental recognition environments

Original experimental coordinate assessment

11OA · DNMT3A PWWP1

Label protein chain O · author chain(s) O · canonical annotation core 292–350

assessed from original mmcifrequires structural reviewELECTRON MICROSCOPY
Original deposited structureProtein/domain evidenceOriginal-coordinate 3D viewerDownload record as JSON
59 / 59Core Cα observations
59Residues with coordinates
198Missing heavy side-chain atoms in observed residues
0Verified local PWWP research-ligand instances

Independent actual-atom audit

Core residue completeness

All residue records CSV

The annotation core is shown only at positions supported by the original protein/entity-to-UniProt mapping. Unobserved residues are separate from observed residues whose side chains lack deposited atoms. Partial occupancies and alternate conformations are recorded independently.

CanonicalAuthor residueComponentSource presenceObserved heavy atomsMissing backbone atomsMissing side-chain atomsAlternate/occupancy warnings
292O:292ILEObserved5CD1, CG1, CG2
293O:293GLYObserved4None
294O:294GLUObserved5CD, CG, OE1, OE2
295O:295LEUObserved5CD1, CD2, CG
296O:296VALObserved5CG1, CG2
297O:297TRPObserved5CD1, CD2, CE2, CE3, CG, CH2, CZ2, CZ3, NE1
298O:298GLYObserved4None
299O:299LYSObserved5CD, CE, CG, NZ
300O:300LEUObserved5CD1, CD2, CG
301O:301ARGObserved5CD, CG, CZ, NE, NH1, NH2
302O:302GLYObserved4None
303O:303PHEObserved5CD1, CD2, CE1, CE2, CG, CZ
304O:304SERObserved5OG
305O:305TRPObserved5CD1, CD2, CE2, CE3, CG, CH2, CZ2, CZ3, NE1
306O:306TRPObserved5CD1, CD2, CE2, CE3, CG, CH2, CZ2, CZ3, NE1
307O:307PROObserved5CD, CG
308O:308GLYObserved4None
309O:309ARGObserved5CD, CG, CZ, NE, NH1, NH2
310O:310ILEObserved5CD1, CG1, CG2
311O:311VALObserved5CG1, CG2
312O:312SERObserved5OG
313O:313TRPObserved5CD1, CD2, CE2, CE3, CG, CH2, CZ2, CZ3, NE1
314O:314TRPObserved5CD1, CD2, CE2, CE3, CG, CH2, CZ2, CZ3, NE1
315O:315METObserved5CE, CG, SD
316O:316THRObserved5CG2, OG1
317O:317GLYObserved4None
318O:318ARGObserved5CD, CG, CZ, NE, NH1, NH2
319O:319SERObserved5OG
320O:320ARGObserved5CD, CG, CZ, NE, NH1, NH2
321O:321ALAObserved5None
322O:322ALAObserved5None
323O:323GLUObserved5CD, CG, OE1, OE2
324O:324GLYObserved4None
325O:325THRObserved5CG2, OG1
326O:326ARGObserved5CD, CG, CZ, NE, NH1, NH2
327O:327TRPObserved5CD1, CD2, CE2, CE3, CG, CH2, CZ2, CZ3, NE1
328O:328VALObserved5CG1, CG2
329O:329METObserved5CE, CG, SD
330O:330TRPObserved5CD1, CD2, CE2, CE3, CG, CH2, CZ2, CZ3, NE1
331O:331PHEObserved5CD1, CD2, CE1, CE2, CG, CZ
332O:332GLYObserved4None
333O:333ASPObserved5CG, OD1, OD2
334O:334GLYObserved4None
335O:335LYSObserved5CD, CE, CG, NZ
336O:336PHEObserved5CD1, CD2, CE1, CE2, CG, CZ
337O:337SERObserved5OG
338O:338VALObserved5CG1, CG2
339O:339VALObserved5CG1, CG2
340O:340CYSObserved5SG
341O:341VALObserved5CG1, CG2
342O:342GLUObserved5CD, CG, OE1, OE2
343O:343LYSObserved5CD, CE, CG, NZ
344O:344LEUObserved5CD1, CD2, CG
345O:345METObserved5CE, CG, SD
346O:346PROObserved5CD, CG
347O:347LEUObserved5CD1, CD2, CG
348O:348SERObserved5OG
349O:349SERObserved5OG
350O:350PHEObserved5CD1, CD2, CE1, CE2, CG, CZ

Exact deposited instances

Experimentally defined PWWP ligand environments

No actual PWWP research-ligand environment was established by the available Phase 6C coordinates. This does not imply that the domain is inactive or that no ligands have been reported elsewhere.

Source and interpretation

PDB source: 11OA; domain: UP:Q9Y6K1:PWWP1.

Original coordinate SHA-256: 22b69191b56482b52a2cc8a8a6f517b143b90300e647239a8ef53c45b3c5873c. The program never creates modeled missing atoms, rescores affinities, or declares a docking-ready receptor. Official validation reports and experimental maps were not independently inspected.