39 sequence-qualified evolutionary PWWP instances
Domain-level structural evidence gaps
An inventory of experimental coordinates, source-classified ligand sites and the limited source-linked biochemical context; these priorities are evidence-completeness categories, not inferred target druggability or novel biological functions.
| Gene / PWWP domain | Observed-core mappings | Deposited ligand instances | Source-linked assay rows | Experimental reference | Evidence status |
|---|---|---|---|---|---|
| 28H13_90 · PWWP1 | 1 / 1 | 0 | 0 | Not selected | A: observed domain, site chemistry not experimentally ligand-defined3 evidence qualifiers
|
| ARID4A · PWWP1 | 4 / 4 | 0 | 0 | 7V8N | A: observed domain, site chemistry not experimentally ligand-defined2 evidence qualifiers
|
| BRPF3 · PWWP1 | 2 / 2 | 0 | 0 | 3PFS | A: observed domain, site chemistry not experimentally ligand-defined2 evidence qualifiers
|
| DNMT3A · PWWP1 | 31 / 104 | 0 | 1 | 3LLR | A: observed domain, site chemistry not experimentally ligand-defined2 evidence qualifiers
|
| Dnmt3b · PWWP1 | 1 / 1 | 0 | 0 | Not selected | A: observed domain, site chemistry not experimentally ligand-defined3 evidence qualifiers
|
| HDGF · PWWP1 | 3 / 3 | 0 | 0 | 1RI0 | A: observed domain, site chemistry not experimentally ligand-defined2 evidence qualifiers
|
| HDGFL3 · PWWP1 | 11 / 11 | 0 | 1 | 6IIP | A: observed domain, site chemistry not experimentally ligand-defined2 evidence qualifiers
|
| Hdgf · PWWP1 | 4 / 4 | 0 | 0 | Not selected | A: observed domain, site chemistry not experimentally ligand-defined3 evidence qualifiers
|
| Hdgfl3 · PWWP1 | 1 / 1 | 0 | 0 | Not selected | A: observed domain, site chemistry not experimentally ligand-defined3 evidence qualifiers
|
| IOC4 · PWWP1 | 1 / 1 | 0 | 0 | Not selected | A: observed domain, site chemistry not experimentally ligand-defined3 evidence qualifiers
|
| Jasper · PWWP1 | 25 / 25 | 0 | 0 | Not selected | A: observed domain, site chemistry not experimentally ligand-defined3 evidence qualifiers
|
| MSH6 · PWWP1 | 2 / 3 | 0 | 0 | 6OQM | A: observed domain, site chemistry not experimentally ligand-defined2 evidence qualifiers
|
| NSD3 · PWWP2 | 2 / 6 | 0 | 0 | 4RXJ | A: observed domain, site chemistry not experimentally ligand-defined2 evidence qualifiers
|
| PSIP1 · PWWP1 | 18 / 48 | 0 | 3 | 2M16 | A: observed domain, site chemistry not experimentally ligand-defined2 evidence qualifiers
|
| PWWP2B · PWWP1 | 1 / 1 | 0 | 0 | 4LD6 | A: observed domain, site chemistry not experimentally ligand-defined2 evidence qualifiers
|
| PWWP3A · PWWP1 | 4 / 4 | 0 | 0 | 3PMI | A: observed domain, site chemistry not experimentally ligand-defined2 evidence qualifiers
|
| ZMYND11 · PWWP1 | 1 / 1 | 0 | 0 | 4NS5 | A: observed domain, site chemistry not experimentally ligand-defined2 evidence qualifiers
|
| ZMYND8 · PWWP1 | 6 / 6 | 0 | 0 | 9T2G | A: observed domain, site chemistry not experimentally ligand-defined2 evidence qualifiers
|
| Zmynd11 · PWWP1 | 3 / 3 | 0 | 0 | Not selected | A: observed domain, site chemistry not experimentally ligand-defined3 evidence qualifiers
|
| pdp1 · PWWP1 | 1 / 1 | 0 | 0 | Not selected | A: observed domain, site chemistry not experimentally ligand-defined3 evidence qualifiers
|
| pdp2 · PWWP1 | 1 / 1 | 0 | 0 | Not selected | A: observed domain, site chemistry not experimentally ligand-defined3 evidence qualifiers
|
| BRD1 · PWWP1 | 8 / 8 | 2 | 0 | 4Z02 | B: ligand site observed, biochemical context needs domain resolution2 evidence qualifiers
|
| BRPF1 · PWWP1 | 17 / 17 | 1 | 0 | 3L42 | B: ligand site observed, biochemical context needs domain resolution3 evidence qualifiers
|
| A0A494C071 · PWWP1 | 0 / 0 | 0 | 0 | Not selected | C: experimental PWWP core not observed in frozen inventory2 evidence qualifiers
|
| NSD2 · PWWP2 | 0 / 4 | 0 | 0 | Not selected | C: experimental PWWP core not observed in frozen inventory2 evidence qualifiers
|
| Q49A26 · PWWP1 | 0 / 0 | 0 | 0 | Not selected | C: experimental PWWP core not observed in frozen inventory2 evidence qualifiers
|
| Q4LE39 · PWWP1 | 0 / 0 | 0 | 0 | Not selected | C: experimental PWWP core not observed in frozen inventory2 evidence qualifiers
|
| Q504Y3 · PWWP1 | 0 / 0 | 0 | 0 | Not selected | C: experimental PWWP core not observed in frozen inventory2 evidence qualifiers
|
| Q5H9M0 · PWWP1 | 0 / 0 | 0 | 0 | Not selected | C: experimental PWWP core not observed in frozen inventory2 evidence qualifiers
|
| Q5TGJ6 · PWWP1 | 0 / 0 | 0 | 0 | Not selected | C: experimental PWWP core not observed in frozen inventory2 evidence qualifiers
|
| Q96L73 · PWWP1 | 0 / 0 | 0 | 0 | Not selected | C: experimental PWWP core not observed in frozen inventory2 evidence qualifiers
|
| Q96L73 · PWWP2 | 0 / 0 | 0 | 0 | Not selected | C: experimental PWWP core not observed in frozen inventory2 evidence qualifiers
|
| Q96N64 · PWWP1 | 0 / 0 | 0 | 0 | Not selected | C: experimental PWWP core not observed in frozen inventory2 evidence qualifiers
|
| Q9H0M4 · PWWP1 | 0 / 0 | 0 | 0 | Not selected | C: experimental PWWP core not observed in frozen inventory2 evidence qualifiers
|
| Q9P267 · PWWP1 | 0 / 0 | 0 | 0 | Not selected | C: experimental PWWP core not observed in frozen inventory2 evidence qualifiers
|
| DNMT3B · PWWP1 | 28 / 86 | 17 | 1 | 5NRR | D: characterized domain, targeted uncertainty review1 evidence qualifiers
|
| HDGFL2 · PWWP1 | 252 / 252 | 176 | 5 | 8Z6O | D: characterized domain, targeted uncertainty review2 evidence qualifiers
|
| NSD2 · PWWP1 | 51 / 51 | 78 | 28 | 9FOC | D: characterized domain, targeted uncertainty review2 evidence qualifiers
|
| NSD3 · PWWP1 | 17 / 17 | 9 | 9 | 6G25 | D: characterized domain, targeted uncertainty review1 evidence qualifiers
|
Counts are source-versioned and refer to the frozen atlas inventory, not to all published structures or assays in the world. All original evidence is preserved.