Experimental structure
2GFU
NMR solution structure of the PWWP domain of Mismatch repair protein hMSH6
Original coordinates
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Original coordinates are available from a locally verified historical archive or the bundled source and load on request.
Coordinate coverage
Mapped chains
Label and author chain identifiers are kept separately. Observed Cα counts refer to each mapped annotation core.
| Protein | Label chain | Author chain | Domain | Observed Cα / core | Observed substitutions |
|---|---|---|---|---|---|
| MSH6 | A | ["A"] | UP:P52701:PWWP1 | 63 / 63 | 1 |
Chemical identity
Chemical components and interpretation
| CCD | Name | Role | Full InChIKey |
|---|---|---|---|
| No non-water chemical component in the curated inventory. | |||
Geometry, with defined scope
Independent contact evidence
Inspect 0 retained contact records
| CCD / instance | Protein chain | Contact class | Minimum core / broader domain distance Å |
|---|---|---|---|
| No retained positive proximity record. | |||
Biological partners
No curated macromolecular partner record.
Source interpretation
Focused scientific audit
retain with stated interpretation/caveats. APO supported. Original sequence contains C88S/C108S/C196S versus UniProt; C108S lies within core 92–154. Preserve engineered-sequence caution.