Phase 6C · Actual deposited atom evidence

Experimental structure quality

Which PWWP regions have observed heavy atoms and experimentally defined ligand environments? Inspect the provenance, missing residues, and local contact limitations without generating receptor models or binding predictions.

666Chain/domain inventory rows

22Locally parsed coordinate records

4Experimental research-ligand environments

644All-atom assessment not possible here

Authoritative experimental observations

Source-supported pocket context

Export measured local environments

6G2O · NSD3 PWWP1

Observed EJE environment

One source-tagged experimental research ligand and a locally complete observed annotation core. Residue/ligand contacts are independently recalculated.

Inspect 6G2O atomic assessment

6XCG · NSD2 PWWP1

Three V01 ligand instances

Distinct deposited ligand instances and protein chains are retained. Local alternative-conformer and partial-occupancy annotations are visible separately.

Inspect 6XCG atomic assessment

11OA · DNMT3A PWWP1

Side-chain coordinate gap

Five observed cores contain 990 missing standard side-chain heavy atoms. Thirteen other mapped chains have no observed PWWP-core coordinates.

Inspect 11OA atom evidence

Directly calculated from the bundled coordinates

Measured structural differences

Observed PWWP core missing side-chain heavy atoms, 6G2O zero, 6XCG 4 to 12 and five 11OA cores each 198. — Missing heavy-atom evidence among observed residues; no-core chains are not treated as complete.

Line plot comparing distinct residue contacts across 3.5, 4, 5 and 6 angstrom distance thresholds for four deposited ligand instances. — Simple geometric proximity and sensitivity, not a hydrogen-bond, density-fit or affinity assessment.

All 666 chain/domain records

Structural-quality inventory

Full inventory CSV Assessment CSV

Protein, PDB or domain Protein Domain Processing outcome Observed-core finding Ligand environment

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666 matching chain/domain records. Filters apply to the same assessed row, not a mixture of unrelated structures. Displaying up to 100 records per page.

PDB / label chain	Protein/domain	Core Cα	Original experiment	Observed missing side-chain atoms	Processing	Receptor assessment
7HGS · C	HDGFL2 PWWP1	49 / 58	X-RAY DIFFRACTION · 1.51 Å	Not assessed	coordinates not packaged	not assessed
7HGT · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.57 Å	Not assessed	coordinates not packaged	not assessed
7HGT · B	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.57 Å	Not assessed	coordinates not packaged	not assessed
7HGT · C	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.57 Å	Not assessed	coordinates not packaged	not assessed
7HGU · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.67 Å	Not assessed	coordinates not packaged	not assessed
7HGU · B	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.67 Å	Not assessed	coordinates not packaged	not assessed
7HGU · C	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.67 Å	Not assessed	coordinates not packaged	not assessed
7HGV · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.48 Å	Not assessed	coordinates not packaged	not assessed
7HGV · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.48 Å	Not assessed	coordinates not packaged	not assessed
7HGV · C	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.48 Å	Not assessed	coordinates not packaged	not assessed
7HGW · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.59 Å	Not assessed	coordinates not packaged	not assessed
7HGW · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.59 Å	Not assessed	coordinates not packaged	not assessed
7HGW · C	HDGFL2 PWWP1	52 / 58	X-RAY DIFFRACTION · 1.59 Å	Not assessed	coordinates not packaged	not assessed
7HGX · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.57 Å	Not assessed	coordinates not packaged	not assessed
7HGX · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.57 Å	Not assessed	coordinates not packaged	not assessed
7HGX · C	HDGFL2 PWWP1	51 / 58	X-RAY DIFFRACTION · 1.57 Å	Not assessed	coordinates not packaged	not assessed
7HGY · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.61 Å	Not assessed	coordinates not packaged	not assessed
7HGY · B	HDGFL2 PWWP1	52 / 58	X-RAY DIFFRACTION · 1.61 Å	Not assessed	coordinates not packaged	not assessed
7HGY · C	HDGFL2 PWWP1	55 / 58	X-RAY DIFFRACTION · 1.61 Å	Not assessed	coordinates not packaged	not assessed
7HGZ · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.65 Å	Not assessed	coordinates not packaged	not assessed
7HGZ · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.65 Å	Not assessed	coordinates not packaged	not assessed
7HGZ · C	HDGFL2 PWWP1	51 / 58	X-RAY DIFFRACTION · 1.65 Å	Not assessed	coordinates not packaged	not assessed
7HH0 · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.6 Å	Not assessed	coordinates not packaged	not assessed
7HH0 · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.6 Å	Not assessed	coordinates not packaged	not assessed
7HH0 · C	HDGFL2 PWWP1	52 / 58	X-RAY DIFFRACTION · 1.6 Å	Not assessed	coordinates not packaged	not assessed
7HH1 · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.53 Å	Not assessed	coordinates not packaged	not assessed
7HH1 · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.53 Å	Not assessed	coordinates not packaged	not assessed
7HH1 · C	HDGFL2 PWWP1	52 / 58	X-RAY DIFFRACTION · 1.53 Å	Not assessed	coordinates not packaged	not assessed
7HH2 · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.78 Å	Not assessed	coordinates not packaged	not assessed
7HH2 · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.78 Å	Not assessed	coordinates not packaged	not assessed
7HH2 · C	HDGFL2 PWWP1	51 / 58	X-RAY DIFFRACTION · 1.78 Å	Not assessed	coordinates not packaged	not assessed
7HH3 · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.64 Å	Not assessed	coordinates not packaged	not assessed
7HH3 · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.64 Å	Not assessed	coordinates not packaged	not assessed
7HH3 · C	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.64 Å	Not assessed	coordinates not packaged	not assessed
7HH4 · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.49 Å	Not assessed	coordinates not packaged	not assessed
7HH4 · B	HDGFL2 PWWP1	55 / 58	X-RAY DIFFRACTION · 1.49 Å	Not assessed	coordinates not packaged	not assessed
7HH4 · C	HDGFL2 PWWP1	56 / 58	X-RAY DIFFRACTION · 1.49 Å	Not assessed	coordinates not packaged	not assessed
7HH5 · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.66 Å	Not assessed	coordinates not packaged	not assessed
7HH5 · B	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.66 Å	Not assessed	coordinates not packaged	not assessed
7HH5 · C	HDGFL2 PWWP1	55 / 58	X-RAY DIFFRACTION · 1.66 Å	Not assessed	coordinates not packaged	not assessed
7HH6 · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.71 Å	Not assessed	coordinates not packaged	not assessed
7HH6 · B	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.71 Å	Not assessed	coordinates not packaged	not assessed
7HH6 · C	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.71 Å	Not assessed	coordinates not packaged	not assessed
7HH7 · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.73 Å	Not assessed	coordinates not packaged	not assessed
7HH7 · B	HDGFL2 PWWP1	51 / 58	X-RAY DIFFRACTION · 1.73 Å	Not assessed	coordinates not packaged	not assessed
7HH7 · C	HDGFL2 PWWP1	51 / 58	X-RAY DIFFRACTION · 1.73 Å	Not assessed	coordinates not packaged	not assessed
7HH8 · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.81 Å	Not assessed	coordinates not packaged	not assessed
7HH8 · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.81 Å	Not assessed	coordinates not packaged	not assessed
7HH8 · C	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.81 Å	Not assessed	coordinates not packaged	not assessed
7HH9 · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.54 Å	Not assessed	coordinates not packaged	not assessed
7HH9 · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.54 Å	Not assessed	coordinates not packaged	not assessed
7HH9 · C	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.54 Å	Not assessed	coordinates not packaged	not assessed
7HHA · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.8 Å	Not assessed	coordinates not packaged	not assessed
7HHA · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.8 Å	Not assessed	coordinates not packaged	not assessed
7HHA · C	HDGFL2 PWWP1	55 / 58	X-RAY DIFFRACTION · 1.8 Å	Not assessed	coordinates not packaged	not assessed
7HHB · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.78 Å	Not assessed	coordinates not packaged	not assessed
7HHB · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.78 Å	Not assessed	coordinates not packaged	not assessed
7HHB · C	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.78 Å	Not assessed	coordinates not packaged	not assessed
7HHC · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.59 Å	Not assessed	coordinates not packaged	not assessed
7HHC · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.59 Å	Not assessed	coordinates not packaged	not assessed
7HHC · C	HDGFL2 PWWP1	52 / 58	X-RAY DIFFRACTION · 1.59 Å	Not assessed	coordinates not packaged	not assessed
7HHD · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.57 Å	Not assessed	coordinates not packaged	not assessed
7HHD · B	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.57 Å	Not assessed	coordinates not packaged	not assessed
7HHD · C	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.57 Å	Not assessed	coordinates not packaged	not assessed
7HHE · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 2.04 Å	Not assessed	coordinates not packaged	not assessed
7HHE · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 2.04 Å	Not assessed	coordinates not packaged	not assessed
7HHE · C	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 2.04 Å	Not assessed	coordinates not packaged	not assessed
7HHF · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.86 Å	Not assessed	coordinates not packaged	not assessed
7HHF · B	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.86 Å	Not assessed	coordinates not packaged	not assessed
7HHF · C	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.86 Å	Not assessed	coordinates not packaged	not assessed
7HHG · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.5 Å	Not assessed	coordinates not packaged	not assessed
7HHG · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.5 Å	Not assessed	coordinates not packaged	not assessed
7HHG · C	HDGFL2 PWWP1	51 / 58	X-RAY DIFFRACTION · 1.5 Å	Not assessed	coordinates not packaged	not assessed
7HHH · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.69 Å	Not assessed	coordinates not packaged	not assessed
7HHH · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.69 Å	Not assessed	coordinates not packaged	not assessed
7HHH · C	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.69 Å	Not assessed	coordinates not packaged	not assessed
7HHI · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 2.11 Å	Not assessed	coordinates not packaged	not assessed
7HHI · B	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 2.11 Å	Not assessed	coordinates not packaged	not assessed
7HHI · C	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 2.11 Å	Not assessed	coordinates not packaged	not assessed
7HHJ · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.78 Å	Not assessed	coordinates not packaged	not assessed
7HHJ · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.78 Å	Not assessed	coordinates not packaged	not assessed
7HHJ · C	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.78 Å	Not assessed	coordinates not packaged	not assessed
7HHK · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.94 Å	Not assessed	coordinates not packaged	not assessed
7HHK · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.94 Å	Not assessed	coordinates not packaged	not assessed
7HHK · C	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.94 Å	Not assessed	coordinates not packaged	not assessed
7HHL · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.71 Å	Not assessed	coordinates not packaged	not assessed
7HHL · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.71 Å	Not assessed	coordinates not packaged	not assessed
7HHL · C	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.71 Å	Not assessed	coordinates not packaged	not assessed
7HHM · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.78 Å	Not assessed	coordinates not packaged	not assessed
7HHM · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.78 Å	Not assessed	coordinates not packaged	not assessed
7HHM · C	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.78 Å	Not assessed	coordinates not packaged	not assessed
7HHN · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.77 Å	Not assessed	coordinates not packaged	not assessed
7HHN · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.77 Å	Not assessed	coordinates not packaged	not assessed
7HHN · C	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.77 Å	Not assessed	coordinates not packaged	not assessed
7HHO · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.76 Å	Not assessed	coordinates not packaged	not assessed
7HHO · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.76 Å	Not assessed	coordinates not packaged	not assessed
7HHO · C	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.76 Å	Not assessed	coordinates not packaged	not assessed
7HHP · A	HDGFL2 PWWP1	58 / 58	X-RAY DIFFRACTION · 1.78 Å	Not assessed	coordinates not packaged	not assessed
7HHP · B	HDGFL2 PWWP1	54 / 58	X-RAY DIFFRACTION · 1.78 Å	Not assessed	coordinates not packaged	not assessed
7HHP · C	HDGFL2 PWWP1	53 / 58	X-RAY DIFFRACTION · 1.78 Å	Not assessed	coordinates not packaged	not assessed

Methods, receptor qualifications & downloads

One independent Gemmi parse checked first-model experimental protein atoms against the earlier Biopython results. Atom-name completeness uses the mmCIF's own standard amino-acid component definitions, excludes hydrogens, and never interprets missing coordinates as chemical inactivity. Ligand–residue geometric contacts use a declared 5 Å primary cutoff with sensitivity analyses, and are not hydrogen bonds, binding energies or density validation.

Residue and missing-atom table Atom-pair distance evidence 11OA audit Source hashes and methods