STRUCTURAL BIOLOGY & CHEMICAL EVIDENCEDataset v1.2 · Phase 6D · Comparative experimental recognition environments

Exact scientific data · reusable graphics

Scientific figures.

Six linked views of PWWP evolution, architecture, residues, structures and chemical evidence. Inspect a figure, then take its source-linked SVG or high-resolution PNG.

Figures A–F · light & dark

Figure A

Supported PWWP relationships

The original unrooted support-collapsed tree, with source branch support and observed-core structure counts.

Figure A: Supported PWWP relationships — light themeFigure A: Supported PWWP relationships — dark theme

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Figure B

Tree with protein architecture

The same domain tips aligned with canonical protein architecture, analyzed cores and selected construct intervals.

Figure B: Tree with protein architecture — light themeFigure B: Tree with protein architecture — dark theme

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Figure C

Tree with scientific evidence

Shared tree rows connect each domain to its structural and chemical evidence in the curated snapshot.

Figure C: Tree with scientific evidence — light themeFigure C: Tree with scientific evidence — dark theme

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Figure D

Residue conservation and source annotations

Seven HDGF/PSIP1-clade sequences, the original alignment mask, descriptive conservation, source cage annotations and deposited contacts.

Figure D: Residue conservation and source annotations — light themeFigure D: Residue conservation and source annotations — dark theme

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Figure E

Chemical evidence across human domains

Thirty human domain rows with separate exact-bound, measured-bioactivity-only and association-only profile counts.

Figure E: Chemical evidence across human domains — light themeFigure E: Chemical evidence across human domains — dark theme

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Figure F

NSD2 PWWP1 and NSD3 PWWP1

Frozen Cα coordinates under the original least-squares transform, domain-specific evidence and six separate source observations.

Figure F: NSD2 PWWP1 and NSD3 PWWP1 — light themeFigure F: NSD2 PWWP1 and NSD3 PWWP1 — dark theme

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Reproducible scientific exports

Sources, geometry & methods.

PWWP-PHASE5-FIGURES-1.0.0

The exact source snapshot, shared row geometry and interpretation notes accompany the figures. The figure manifest contains the output and source hashes. Its own served-byte SHA-256 is shown below; supporting files are verified against the hashes recorded in that manifest.

Manifest SHA-256 and export scope

c4765569fe54f0fd5462fe735085eecf8fa55ef0c909c7eddbee9fed5d91756e

12 SVG files and 12 high-resolution PNG files; six figures in two themes. PNGs were rendered at 3× from their corresponding SVGs. Preview thumbnails in the release package are separate inspection aids and are not substituted for these exports.

Tree edge spacing in the support-collapsed representation has no evolutionary distance scale. Descriptive conservation, coordinate proximity and experimental bioactivity remain distinct evidence types. Figure E preserves target-specific profile denominators; Figure F preserves separate source observations.