Phase 6D · Source-based structural correspondence
Experimental domain comparison
Two original deposited PWWP structures and the source-qualified least-squares comparison. Alignment values are descriptive geometry; ligand potency or binding function is not inferred.
51Globally mapped Cα pairs
3.210 ÅGlobal aligned-core RMSD
22Local mapped Cα pairs
3.293 ÅLocal reference-region RMSD
ZMYND8 · 9T2G
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NSD3 · 6G25
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Structural fit and evidence
- Comparison status
- Calculated
- Whole core
- qualified_frozen_MSA_Calpha
- Local region
- NSD2_ligand_site_homology_transferred_reference_patch
- Source reference
- Frozen qualified 39-instance evolutionary alignment and independently observed representative core coordinates
Downloadable precomputed rigid transformation (B into A)
Row-vector convention: coordinate B × R + t → coordinate A. These values correspond to the listed mapped Cα positions and exclude reflections.
Rotation: [[0.6447570502763305, -0.1235813503102651, 0.7543314894490731], [-0.5231224764946935, 0.6482056460779478, 0.553328397047115], [-0.5573430009473739, -0.7513701419727579, 0.3532869783148165]]\nTranslation (Å): [-17.532826294701053, -3.157146943559834, -20.021587022958744]\nAligned MSA columns: ["136", "137", "138", "139", "140", "141", "142", "143", "144", "145", "146", "152", "153", "154", "155", "156", "157", "158", "159", "160", "161", "162", "163", "164", "165", "166", "167", "24", "25", "26", "27", "28", "29", "30", "31", "32", "43", "44", "45", "46", "47", "48", "49", "50", "51", "52", "53", "54", "55", "56", "57"]