Phase 6D · Source-based structural correspondence
Experimental domain comparison
Two original deposited PWWP structures and the source-qualified least-squares comparison. Alignment values are descriptive geometry; ligand potency or binding function is not inferred.
57Globally mapped Cα pairs
3.136 ÅGlobal aligned-core RMSD
23Local mapped Cα pairs
2.670 ÅLocal reference-region RMSD
DNMT3B · 5NRR
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NSD3 · 6G25
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Structural fit and evidence
- Comparison status
- Calculated
- Whole core
- qualified_frozen_MSA_Calpha
- Local region
- NSD2_ligand_site_homology_transferred_reference_patch
- Source reference
- Frozen qualified 39-instance evolutionary alignment and independently observed representative core coordinates
Downloadable precomputed rigid transformation (B into A)
Row-vector convention: coordinate B × R + t → coordinate A. These values correspond to the listed mapped Cα positions and exclude reflections.
Rotation: [[0.6488141149657609, 0.6010849973653329, -0.4666230493273062], [0.6700499418664445, -0.1606514151885111, 0.7247235322539919], [0.3606567892414753, -0.7828716042495386, -0.5069898733049641]]\nTranslation (Å): [-73.33980084114569, 66.65955708848237, -91.36900336616976]\nAligned MSA columns: ["132", "133", "134", "135", "136", "137", "138", "139", "140", "141", "142", "143", "144", "145", "146", "152", "153", "154", "155", "156", "157", "158", "159", "160", "161", "162", "163", "164", "165", "166", "167", "24", "25", "26", "27", "28", "29", "30", "31", "32", "43", "44", "45", "46", "47", "48", "49", "50", "51", "52", "53", "54", "55", "56", "57", "58", "59"]