Phase 6D · Source-based structural correspondence
Experimental domain comparison
Two original deposited PWWP structures and the source-qualified least-squares comparison. Alignment values are descriptive geometry; ligand potency or binding function is not inferred.
57Globally mapped Cα pairs
3.390 ÅGlobal aligned-core RMSD
23Local mapped Cα pairs
3.405 ÅLocal reference-region RMSD
NSD3 · 4RXJ
Source label chain A · original mmCIF hash verified before rendering
Browser/WebGL and exact source integrity will be checked when loaded.
NSD3 · 6G25
Source label chain A · original mmCIF hash verified before rendering
Browser/WebGL and exact source integrity will be checked when loaded.
Structural fit and evidence
- Comparison status
- Calculated
- Whole core
- qualified_frozen_MSA_Calpha
- Local region
- NSD2_ligand_site_homology_transferred_reference_patch
- Source reference
- Frozen qualified 39-instance evolutionary alignment and independently observed representative core coordinates
Downloadable precomputed rigid transformation (B into A)
Row-vector convention: coordinate B × R + t → coordinate A. These values correspond to the listed mapped Cα positions and exclude reflections.
Rotation: [[0.6164146578542617, 0.7874203790039624, 0.0014547548481822687], [0.735798449927731, -0.5766595335996273, 0.3550555215633303], [0.2804168516091016, -0.21779102148140983, -0.9348440834148344]]\nTranslation (Å): [-55.20524993397275, 27.341784931935653, 4.201236884760002]\nAligned MSA columns: ["132", "133", "134", "135", "136", "137", "138", "139", "140", "141", "142", "143", "144", "145", "146", "152", "153", "154", "155", "156", "157", "158", "159", "160", "161", "162", "163", "164", "165", "166", "167", "24", "25", "26", "27", "28", "29", "30", "31", "32", "43", "44", "45", "46", "47", "48", "49", "50", "51", "52", "53", "54", "55", "56", "57", "58", "59"]