Phase 6D · Source-based structural correspondence
Experimental domain comparison
Two original deposited PWWP structures and the source-qualified least-squares comparison. Alignment values are descriptive geometry; ligand potency or binding function is not inferred.
51Globally mapped Cα pairs
3.649 ÅGlobal aligned-core RMSD
22Local mapped Cα pairs
3.614 ÅLocal reference-region RMSD
ZMYND11 · 4NS5
Source label chain A · original mmCIF hash verified before rendering
Browser/WebGL and exact source integrity will be checked when loaded.
NSD3 · 6G25
Source label chain A · original mmCIF hash verified before rendering
Browser/WebGL and exact source integrity will be checked when loaded.
Structural fit and evidence
- Comparison status
- Calculated
- Whole core
- qualified_frozen_MSA_Calpha
- Local region
- NSD2_ligand_site_homology_transferred_reference_patch
- Source reference
- Frozen qualified 39-instance evolutionary alignment and independently observed representative core coordinates
Downloadable precomputed rigid transformation (B into A)
Row-vector convention: coordinate B × R + t → coordinate A. These values correspond to the listed mapped Cα positions and exclude reflections.
Rotation: [[0.3078488781093723, 0.38106830212366466, -0.8717889752476732], [-0.7233207370043361, 0.6889952284077591, 0.04574589217452747], [0.6180907535842164, 0.6165002225043613, 0.4877410132291193]]\nTranslation (Å): [27.45431847559466, 2.133050339056659, 12.883736447011538]\nAligned MSA columns: ["136", "137", "138", "139", "140", "141", "142", "143", "144", "145", "146", "152", "153", "154", "155", "156", "157", "158", "159", "160", "161", "162", "163", "164", "165", "166", "167", "24", "25", "26", "27", "28", "29", "30", "31", "32", "43", "44", "45", "46", "47", "48", "49", "50", "51", "52", "53", "54", "55", "56", "57"]