Phase 6D · Source-based structural correspondence
Experimental domain comparison
Two original deposited PWWP structures and the source-qualified least-squares comparison. Alignment values are descriptive geometry; ligand potency or binding function is not inferred.
57Globally mapped Cα pairs
2.709 ÅGlobal aligned-core RMSD
23Local mapped Cα pairs
2.432 ÅLocal reference-region RMSD
BRPF1 · 3L42
Source label chain A · original mmCIF hash verified before rendering
Browser/WebGL and exact source integrity will be checked when loaded.
NSD3 · 6G25
Source label chain A · original mmCIF hash verified before rendering
Browser/WebGL and exact source integrity will be checked when loaded.
Structural fit and evidence
- Comparison status
- Calculated
- Whole core
- qualified_frozen_MSA_Calpha
- Local region
- NSD2_ligand_site_homology_transferred_reference_patch
- Source reference
- Frozen qualified 39-instance evolutionary alignment and independently observed representative core coordinates
Downloadable precomputed rigid transformation (B into A)
Row-vector convention: coordinate B × R + t → coordinate A. These values correspond to the listed mapped Cα positions and exclude reflections.
Rotation: [[0.6694936349897584, -0.6169675078828492, 0.4136778540422786], [-0.2505630753015052, -0.7118336459916889, -0.6561333749548418], [0.6992827882935848, 0.3356247229436552, -0.6311573712992209]]\nTranslation (Å): [20.59076090078857, -7.15497004135889, -10.925746392940537]\nAligned MSA columns: ["132", "133", "134", "135", "136", "137", "138", "139", "140", "141", "142", "143", "144", "145", "146", "152", "153", "154", "155", "156", "157", "158", "159", "160", "161", "162", "163", "164", "165", "166", "167", "24", "25", "26", "27", "28", "29", "30", "31", "32", "43", "44", "45", "46", "47", "48", "49", "50", "51", "52", "53", "54", "55", "56", "57", "58", "59"]