Phase 6D · Source-based structural correspondence
Experimental domain comparison
Two original deposited PWWP structures and the source-qualified least-squares comparison. Alignment values are descriptive geometry; ligand potency or binding function is not inferred.
57Globally mapped Cα pairs
1.524 ÅGlobal aligned-core RMSD
23Local mapped Cα pairs
1.221 ÅLocal reference-region RMSD
MSH6 · 6OQM
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NSD3 · 6G25
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Structural fit and evidence
- Comparison status
- Calculated
- Whole core
- qualified_frozen_MSA_Calpha
- Local region
- NSD2_ligand_site_homology_transferred_reference_patch
- Source reference
- Frozen qualified 39-instance evolutionary alignment and independently observed representative core coordinates
Downloadable precomputed rigid transformation (B into A)
Row-vector convention: coordinate B × R + t → coordinate A. These values correspond to the listed mapped Cα positions and exclude reflections.
Rotation: [[-0.25666976857798246, -0.23136740534646305, -0.9383974390637305], [-0.08989466790831839, 0.9724302623823123, -0.21517047540199108], [0.9623095024885571, 0.029129170024406396, -0.27039214647232607]]\nTranslation (Å): [-5.140428351149328, 2.774903700896237, 65.89156426928378]\nAligned MSA columns: ["132", "133", "134", "135", "136", "137", "138", "139", "140", "141", "142", "143", "144", "145", "146", "152", "153", "154", "155", "156", "157", "158", "159", "160", "161", "162", "163", "164", "165", "166", "167", "24", "25", "26", "27", "28", "29", "30", "31", "32", "43", "44", "45", "46", "47", "48", "49", "50", "51", "52", "53", "54", "55", "56", "57", "58", "59"]