Phase 6D · Source-based structural correspondence
Experimental domain comparison
Two original deposited PWWP structures and the source-qualified least-squares comparison. Alignment values are descriptive geometry; ligand potency or binding function is not inferred.
56Globally mapped Cα pairs
1.533 ÅGlobal aligned-core RMSD
23Local mapped Cα pairs
0.590 ÅLocal reference-region RMSD
NSD2 · 9FOC
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NSD3 · 6G25
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Structural fit and evidence
- Comparison status
- Calculated
- Whole core
- qualified_frozen_MSA_Calpha
- Local region
- NSD2_ligand_site_homology_transferred_reference_patch
- Source reference
- Frozen qualified 39-instance evolutionary alignment and independently observed representative core coordinates
Downloadable precomputed rigid transformation (B into A)
Row-vector convention: coordinate B × R + t → coordinate A. These values correspond to the listed mapped Cα positions and exclude reflections.
Rotation: [[-0.06207560678973585, 0.8672651752355649, 0.4939612685882465], [-0.6139987815742449, 0.3569998591554261, -0.7039578089547329], [-0.7868621958558105, -0.34699022520328954, 0.510338778015488]]\nTranslation (Å): [10.572507077769778, 59.682026971506, 140.50127699976252]\nAligned MSA columns: ["132", "133", "134", "135", "136", "137", "138", "139", "140", "141", "142", "143", "144", "145", "146", "152", "153", "154", "155", "156", "157", "158", "159", "160", "161", "162", "163", "164", "165", "166", "24", "25", "26", "27", "28", "29", "30", "31", "32", "43", "44", "45", "46", "47", "48", "49", "50", "51", "52", "53", "54", "55", "56", "57", "58", "59"]