STRUCTURAL BIOLOGY & CHEMICAL EVIDENCEDataset v1.2 · Phase 6D · Comparative experimental recognition environments

Published assay observation

MR837 (3f) and NSD2

PWWP:ASSAY:0002

direct binding affinity

Reported observation

SPR Kd

= 3.4 µM ± 0.4

Reported uncertainty; definition uncurated

Target domain
UP:O96028:PWWP1
Assay construct
Uncurated–Uncurated
Identity scope
exact single CCD identity

Evidence provenance

Primary source

PMID:33522809

Results; Figure S6

Verification scope
primary_article_selected_indexed_full_text_passages; original figures and supplement not independently opened
Assay and verification JSON

Field-level provenance

Assay conditions and source verification

Missing information is not proof of absence. The v1.2 source overlay separates not reported in inspected material, not inspected, not transcribed and not applicable.

buffer
Uncurated; field-level source review not performed for this record
pH
Uncurated; field-level source review not performed for this record
DMSO percent
0.5
temperature C
Uncurated; field-level source review not performed for this record
replicates
Uncurated; field-level source review not performed for this record
uncertainty type
Uncurated; field-level source review not performed for this record

Structure → Component → Assay

Exact identity contact links

16 contact links

6UE6 Q5D

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

6UE6 Q5D

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

6UE6 Q5D

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

6UE6 Q5D

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

6UE6 Q5D

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

6UE6 Q5D

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

6UE6 Q5D

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

6UE6 Q5D

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

6UE6 Q5D

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

6UE6 Q5D

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

6UE6 Q5D

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

6UE6 Q5D

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

6UE6 Q5D

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

6UE6 Q5D

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

6UE6 Q5D

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed

6UE6 Q5D

native annotation core contact

same exact chemical identity and native domain; construct equivalence not assumed