{
  "science_site": null,
  "structure": {
    "pdb_id": "8PEP",
    "title": "H3K36me2 nucleosome-LEDGF/p75 PWWP domain complex - pose 2",
    "method": "[\"ELECTRON MICROSCOPY\"]",
    "resolution_angstrom": 3.33,
    "primary_classification": "Complexes",
    "observed_PWWP": 1,
    "review_required": 0,
    "review_reasons": "[]",
    "release_date": "2023-08-16T00:00:00.000+00:00",
    "source_url": "https://www.rcsb.org/structure/8PEP",
    "coordinate_url": "https://files.rcsb.org/download/8PEP.cif",
    "original_cif_sha256": "ae0e6f6a194df30c8e2861262fea362e7bc23da27b18f70d0af5fdf0372233af",
    "classification_status": "v1 classification retained; independent coverage/contact evidence and sampled scientific audit are separate layers"
  },
  "chains": [
    {
      "auth_asym_ids_observed": "[\"K\"]",
      "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
      "chain_id": "PDB:8PEP:CHAIN:J:UP:O75475",
      "core_definition_source": "UniProtKB reviewed feature",
      "domain_id": "UP:O75475:PWWP1",
      "entity_id": "7",
      "gene": "PSIP1",
      "isolated_PWWP_containing_construct_candidate": 0,
      "label_asym_id": "J",
      "mapped_construct_ranges": "[[1, 530]]",
      "native_core_end": 64,
      "native_core_start": 1,
      "observed_chain_residue_count": 86,
      "observed_core_residue_count": 59,
      "pdb_id": "8PEP",
      "pfam_entity_ranges": "[[8, 89]]",
      "protein_id": "UP:O75475",
      "source_entity_json": "Structures/PSIP1__HUMAN__O75475/Complexes/8PEP/polymer_entities.json",
      "source_entity_json_sha256": "d9857f31b4706fc2ad36db14b3714eb360c7a9106ed0735dfe51e4c1662c5145"
    },
    {
      "auth_asym_ids_observed": "[\"L\"]",
      "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
      "chain_id": "PDB:8PEP:CHAIN:L:UP:O75475",
      "core_definition_source": "UniProtKB reviewed feature",
      "domain_id": "UP:O75475:PWWP1",
      "entity_id": "7",
      "gene": "PSIP1",
      "isolated_PWWP_containing_construct_candidate": 0,
      "label_asym_id": "L",
      "mapped_construct_ranges": "[[1, 530]]",
      "native_core_end": 64,
      "native_core_start": 1,
      "observed_chain_residue_count": 86,
      "observed_core_residue_count": 59,
      "pdb_id": "8PEP",
      "pfam_entity_ranges": "[[8, 89]]",
      "protein_id": "UP:O75475",
      "source_entity_json": "Structures/PSIP1__HUMAN__O75475/Complexes/8PEP/polymer_entities.json",
      "source_entity_json_sha256": "d9857f31b4706fc2ad36db14b3714eb360c7a9106ed0735dfe51e4c1662c5145"
    }
  ],
  "chain": {
    "auth_asym_ids_observed": "[\"L\"]",
    "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
    "chain_id": "PDB:8PEP:CHAIN:L:UP:O75475",
    "core_definition_source": "UniProtKB reviewed feature",
    "domain_id": "UP:O75475:PWWP1",
    "entity_id": "7",
    "gene": "PSIP1",
    "isolated_PWWP_containing_construct_candidate": 0,
    "label_asym_id": "L",
    "mapped_construct_ranges": "[[1, 530]]",
    "native_core_end": 64,
    "native_core_start": 1,
    "observed_chain_residue_count": 86,
    "observed_core_residue_count": 59,
    "pdb_id": "8PEP",
    "pfam_entity_ranges": "[[8, 89]]",
    "protein_id": "UP:O75475",
    "source_entity_json": "Structures/PSIP1__HUMAN__O75475/Complexes/8PEP/polymer_entities.json",
    "source_entity_json_sha256": "d9857f31b4706fc2ad36db14b3714eb360c7a9106ed0735dfe51e4c1662c5145"
  },
  "sites": [],
  "site": null,
  "quality": null,
  "contacts": [],
  "comparison": {
    "comparison_id": "8PEP:L:UP:O75475:PWWP1",
    "pdb_id": "8PEP",
    "protein_id": "UP:O75475",
    "gene": "PSIP1",
    "taxonomy_id": "9606",
    "domain_id": "UP:O75475:PWWP1",
    "label_asym_id": "L",
    "auth_asym_ids": "[\"L\"]",
    "first_model": "1",
    "domain_start": 1,
    "domain_end": 64,
    "annotation_core_length": 64,
    "n_observed_CA": 59,
    "core_CA_coverage": 0.921875,
    "v1_observed_any_atom_residues": 59,
    "CA_minus_v1_any_atom": 0,
    "n_common_AF_CA": 59,
    "core_observed_substitutions": 0,
    "substitutions": "[]",
    "duplicate_canonical_positions": "[]",
    "experimental_method": "ELECTRON MICROSCOPY",
    "resolution_angstrom": 3.33,
    "primary_classification": "Complexes",
    "classification_review_required": 0,
    "source_cif": "Structures/PSIP1__HUMAN__O75475/Complexes/8PEP/original.cif",
    "source_sha256": "ae0e6f6a194df30c8e2861262fea362e7bc23da27b18f70d0af5fdf0372233af",
    "mapping_sha256": "d1076d849e4d751bc12872dcf490b7889fd6a4b1340ef1b6b06acbb570d7eab8",
    "comparison_status": "eligible",
    "AF_model_record_id": "AF-O75475-F1:v6",
    "rmsd_all_common_CA": 2.340848,
    "n_AF_CA_ge70": 54,
    "rmsd_AF_ge70_CA": 1.568273,
    "AF_core_mean_plddt": 90.8088
  },
  "assays": [],
  "local_coordinates": true,
  "coordinate_url": "/coordinates/phase6c1/8PEP.cif",
  "interpretation": "Heavy-atom distances use the first deposited model and asymmetric unit, occupancy >0 and retained alternate locations. No symmetry expansion or affinity inference.",
  "quality_scope": "Detailed atom completeness only for the three packaged original-coordinate files; quality uses observed atom-name union across positive-occupancy alternate conformers, with per-alt differences retained. Missing entire residues are separate. Nonstandard amino-acid templates are unassessed. No density reinterpretation, receptor repair, docking or MD.",
  "analysis_id": "PWWP_POCKET_QUALITY_1.0.0",
  "source_conflict": null
}