{
  "science_site": null,
  "structure": {
    "pdb_id": "8QZM",
    "title": "Structure of DNMT3A1 UDR region bound to H2AK119ub nucleosome",
    "method": "[\"ELECTRON MICROSCOPY\"]",
    "resolution_angstrom": 3.1,
    "primary_classification": "Unclassified_Review",
    "observed_PWWP": 0,
    "review_required": 1,
    "review_reasons": "[\"No observed mapped PWWP residues; retained as associated deposition, excluded from experimental PWWP-coordinate counts\"]",
    "release_date": "2024-10-23T00:00:00.000+00:00",
    "source_url": "https://www.rcsb.org/structure/8QZM",
    "coordinate_url": "https://files.rcsb.org/download/8QZM.cif",
    "original_cif_sha256": "df338d612b7680fe4107c27eea6fcefaa8cdfa4e191d355742c1661eab55c7fe",
    "classification_status": "v1 classification retained; independent coverage/contact evidence and sampled scientific audit are separate layers"
  },
  "chains": [
    {
      "auth_asym_ids_observed": "[\"K\"]",
      "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
      "chain_id": "PDB:8QZM:CHAIN:K:UP:Q9Y6K1",
      "core_definition_source": "UniProtKB reviewed feature",
      "domain_id": "UP:Q9Y6K1:PWWP1",
      "entity_id": "7",
      "gene": "DNMT3A",
      "isolated_PWWP_containing_construct_candidate": 0,
      "label_asym_id": "K",
      "mapped_construct_ranges": "[[1, 912]]",
      "native_core_end": 350,
      "native_core_start": 292,
      "observed_chain_residue_count": 24,
      "observed_core_residue_count": 0,
      "pdb_id": "8QZM",
      "pfam_entity_ranges": "[]",
      "protein_id": "UP:Q9Y6K1",
      "source_entity_json": "Structures/DNMT3A__HUMAN__Q9Y6K1/Unclassified_Review/8QZM/polymer_entities.json",
      "source_entity_json_sha256": "f8dcf568f425c0509382ed3cae152fd6dcab6e0f49f8085698eeb9b22fbb525e"
    }
  ],
  "chain": {
    "auth_asym_ids_observed": "[\"K\"]",
    "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
    "chain_id": "PDB:8QZM:CHAIN:K:UP:Q9Y6K1",
    "core_definition_source": "UniProtKB reviewed feature",
    "domain_id": "UP:Q9Y6K1:PWWP1",
    "entity_id": "7",
    "gene": "DNMT3A",
    "isolated_PWWP_containing_construct_candidate": 0,
    "label_asym_id": "K",
    "mapped_construct_ranges": "[[1, 912]]",
    "native_core_end": 350,
    "native_core_start": 292,
    "observed_chain_residue_count": 24,
    "observed_core_residue_count": 0,
    "pdb_id": "8QZM",
    "pfam_entity_ranges": "[]",
    "protein_id": "UP:Q9Y6K1",
    "source_entity_json": "Structures/DNMT3A__HUMAN__Q9Y6K1/Unclassified_Review/8QZM/polymer_entities.json",
    "source_entity_json_sha256": "f8dcf568f425c0509382ed3cae152fd6dcab6e0f49f8085698eeb9b22fbb525e"
  },
  "sites": [],
  "site": null,
  "quality": null,
  "contacts": [],
  "comparison": {
    "comparison_id": "8QZM:K:UP:Q9Y6K1:PWWP1",
    "pdb_id": "8QZM",
    "protein_id": "UP:Q9Y6K1",
    "gene": "DNMT3A",
    "taxonomy_id": "9606",
    "domain_id": "UP:Q9Y6K1:PWWP1",
    "label_asym_id": "K",
    "auth_asym_ids": "[\"K\"]",
    "first_model": "1",
    "domain_start": 292,
    "domain_end": 350,
    "annotation_core_length": 59,
    "n_observed_CA": 0,
    "core_CA_coverage": 0.0,
    "v1_observed_any_atom_residues": 0,
    "CA_minus_v1_any_atom": 0,
    "n_common_AF_CA": 0,
    "core_observed_substitutions": 0,
    "substitutions": "[]",
    "duplicate_canonical_positions": "[]",
    "experimental_method": "ELECTRON MICROSCOPY",
    "resolution_angstrom": 3.1,
    "primary_classification": "Unclassified_Review",
    "classification_review_required": 1,
    "source_cif": "Structures/DNMT3A__HUMAN__Q9Y6K1/Unclassified_Review/8QZM/original.cif",
    "source_sha256": "df338d612b7680fe4107c27eea6fcefaa8cdfa4e191d355742c1661eab55c7fe",
    "mapping_sha256": "83403fb378dae2097d640c90e55c25df4dd86320a8453a65553904833b4026bc",
    "comparison_status": "no_observed_core_CA",
    "AF_model_record_id": "AF-Q9Y6K1-F1:v6",
    "rmsd_all_common_CA": null,
    "n_AF_CA_ge70": 0,
    "rmsd_AF_ge70_CA": null,
    "AF_core_mean_plddt": null
  },
  "assays": [],
  "local_coordinates": true,
  "coordinate_url": "/coordinates/phase6c1/8QZM.cif",
  "interpretation": "Heavy-atom distances use the first deposited model and asymmetric unit, occupancy >0 and retained alternate locations. No symmetry expansion or affinity inference.",
  "quality_scope": "Detailed atom completeness only for the three packaged original-coordinate files; quality uses observed atom-name union across positive-occupancy alternate conformers, with per-alt differences retained. Missing entire residues are separate. Nonstandard amino-acid templates are unassessed. No density reinterpretation, receptor repair, docking or MD.",
  "analysis_id": "PWWP_POCKET_QUALITY_1.0.0",
  "source_conflict": null
}