{
  "science_site": null,
  "structure": {
    "pdb_id": "7LH9",
    "title": "Crystal structure of BRPF2 PWWP domain in complex with DNA",
    "method": "[\"X-RAY DIFFRACTION\"]",
    "resolution_angstrom": 2.6,
    "primary_classification": "Complexes",
    "observed_PWWP": 1,
    "review_required": 0,
    "review_reasons": "[]",
    "release_date": "2021-02-17T00:00:00.000+00:00",
    "source_url": "https://www.rcsb.org/structure/7LH9",
    "coordinate_url": "https://files.rcsb.org/download/7LH9.cif",
    "original_cif_sha256": "16bc43072d6966ab65ffb692c573a44ffac1eb40f56d82639543cb19d9bceeb1",
    "classification_status": "v1 classification retained; independent coverage/contact evidence and sampled scientific audit are separate layers"
  },
  "chains": [
    {
      "auth_asym_ids_observed": "[\"B\"]",
      "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
      "chain_id": "PDB:7LH9:CHAIN:B:UP:O95696",
      "core_definition_source": "UniProtKB reviewed feature",
      "domain_id": "UP:O95696:PWWP1",
      "entity_id": "1",
      "gene": "BRD1",
      "isolated_PWWP_containing_construct_candidate": 1,
      "label_asym_id": "B",
      "mapped_construct_ranges": "[[925, 1049]]",
      "native_core_end": 1012,
      "native_core_start": 929,
      "observed_chain_residue_count": 117,
      "observed_core_residue_count": 84,
      "pdb_id": "7LH9",
      "pfam_entity_ranges": "[[7, 120]]",
      "protein_id": "UP:O95696",
      "source_entity_json": "Structures/BRD1__HUMAN__O95696/Complexes/7LH9/polymer_entities.json",
      "source_entity_json_sha256": "87a9f8a4129c067ed75e25018402e731863fda8c401faa29db9ca9cd842e286e"
    },
    {
      "auth_asym_ids_observed": "[\"D\"]",
      "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
      "chain_id": "PDB:7LH9:CHAIN:D:UP:O95696",
      "core_definition_source": "UniProtKB reviewed feature",
      "domain_id": "UP:O95696:PWWP1",
      "entity_id": "1",
      "gene": "BRD1",
      "isolated_PWWP_containing_construct_candidate": 1,
      "label_asym_id": "D",
      "mapped_construct_ranges": "[[925, 1049]]",
      "native_core_end": 1012,
      "native_core_start": 929,
      "observed_chain_residue_count": 116,
      "observed_core_residue_count": 81,
      "pdb_id": "7LH9",
      "pfam_entity_ranges": "[[7, 120]]",
      "protein_id": "UP:O95696",
      "source_entity_json": "Structures/BRD1__HUMAN__O95696/Complexes/7LH9/polymer_entities.json",
      "source_entity_json_sha256": "87a9f8a4129c067ed75e25018402e731863fda8c401faa29db9ca9cd842e286e"
    },
    {
      "auth_asym_ids_observed": "[\"A\"]",
      "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
      "chain_id": "PDB:7LH9:CHAIN:A:UP:O95696",
      "core_definition_source": "UniProtKB reviewed feature",
      "domain_id": "UP:O95696:PWWP1",
      "entity_id": "1",
      "gene": "BRD1",
      "isolated_PWWP_containing_construct_candidate": 1,
      "label_asym_id": "A",
      "mapped_construct_ranges": "[[925, 1049]]",
      "native_core_end": 1012,
      "native_core_start": 929,
      "observed_chain_residue_count": 112,
      "observed_core_residue_count": 74,
      "pdb_id": "7LH9",
      "pfam_entity_ranges": "[[7, 120]]",
      "protein_id": "UP:O95696",
      "source_entity_json": "Structures/BRD1__HUMAN__O95696/Complexes/7LH9/polymer_entities.json",
      "source_entity_json_sha256": "87a9f8a4129c067ed75e25018402e731863fda8c401faa29db9ca9cd842e286e"
    },
    {
      "auth_asym_ids_observed": "[\"C\"]",
      "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
      "chain_id": "PDB:7LH9:CHAIN:C:UP:O95696",
      "core_definition_source": "UniProtKB reviewed feature",
      "domain_id": "UP:O95696:PWWP1",
      "entity_id": "1",
      "gene": "BRD1",
      "isolated_PWWP_containing_construct_candidate": 1,
      "label_asym_id": "C",
      "mapped_construct_ranges": "[[925, 1049]]",
      "native_core_end": 1012,
      "native_core_start": 929,
      "observed_chain_residue_count": 107,
      "observed_core_residue_count": 71,
      "pdb_id": "7LH9",
      "pfam_entity_ranges": "[[7, 120]]",
      "protein_id": "UP:O95696",
      "source_entity_json": "Structures/BRD1__HUMAN__O95696/Complexes/7LH9/polymer_entities.json",
      "source_entity_json_sha256": "87a9f8a4129c067ed75e25018402e731863fda8c401faa29db9ca9cd842e286e"
    }
  ],
  "chain": {
    "auth_asym_ids_observed": "[\"D\"]",
    "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
    "chain_id": "PDB:7LH9:CHAIN:D:UP:O95696",
    "core_definition_source": "UniProtKB reviewed feature",
    "domain_id": "UP:O95696:PWWP1",
    "entity_id": "1",
    "gene": "BRD1",
    "isolated_PWWP_containing_construct_candidate": 1,
    "label_asym_id": "D",
    "mapped_construct_ranges": "[[925, 1049]]",
    "native_core_end": 1012,
    "native_core_start": 929,
    "observed_chain_residue_count": 116,
    "observed_core_residue_count": 81,
    "pdb_id": "7LH9",
    "pfam_entity_ranges": "[[7, 120]]",
    "protein_id": "UP:O95696",
    "source_entity_json": "Structures/BRD1__HUMAN__O95696/Complexes/7LH9/polymer_entities.json",
    "source_entity_json_sha256": "87a9f8a4129c067ed75e25018402e731863fda8c401faa29db9ca9cd842e286e"
  },
  "sites": [],
  "site": null,
  "quality": null,
  "contacts": [],
  "comparison": {
    "comparison_id": "7LH9:D:UP:O95696:PWWP1",
    "pdb_id": "7LH9",
    "protein_id": "UP:O95696",
    "gene": "BRD1",
    "taxonomy_id": "9606",
    "domain_id": "UP:O95696:PWWP1",
    "label_asym_id": "D",
    "auth_asym_ids": "[\"D\"]",
    "first_model": "1",
    "domain_start": 929,
    "domain_end": 1012,
    "annotation_core_length": 84,
    "n_observed_CA": 81,
    "core_CA_coverage": 0.964286,
    "v1_observed_any_atom_residues": 81,
    "CA_minus_v1_any_atom": 0,
    "n_common_AF_CA": 81,
    "core_observed_substitutions": 0,
    "substitutions": "[]",
    "duplicate_canonical_positions": "[]",
    "experimental_method": "X-RAY DIFFRACTION",
    "resolution_angstrom": 2.6,
    "primary_classification": "Complexes",
    "classification_review_required": 0,
    "source_cif": "Structures/BRD1__HUMAN__O95696/Complexes/7LH9/original.cif",
    "source_sha256": "16bc43072d6966ab65ffb692c573a44ffac1eb40f56d82639543cb19d9bceeb1",
    "mapping_sha256": "2373b01a6e35b38594beea85337643292ac6017a53522e80c4359b6ec183700d",
    "comparison_status": "eligible",
    "AF_model_record_id": "AF-O95696-F1:v6",
    "rmsd_all_common_CA": 0.721817,
    "n_AF_CA_ge70": 76,
    "rmsd_AF_ge70_CA": 0.634023,
    "AF_core_mean_plddt": 87.284
  },
  "assays": [],
  "local_coordinates": true,
  "coordinate_url": "/coordinates/phase6c1/7LH9.cif",
  "interpretation": "Heavy-atom distances use the first deposited model and asymmetric unit, occupancy >0 and retained alternate locations. No symmetry expansion or affinity inference.",
  "quality_scope": "Detailed atom completeness only for the three packaged original-coordinate files; quality uses observed atom-name union across positive-occupancy alternate conformers, with per-alt differences retained. Missing entire residues are separate. Nonstandard amino-acid templates are unassessed. No density reinterpretation, receptor repair, docking or MD.",
  "analysis_id": "PWWP_POCKET_QUALITY_1.0.0",
  "source_conflict": null
}