{
  "science_site": null,
  "structure": {
    "pdb_id": "6G3P",
    "title": "X-ray structure of seleno-methionine labelled NSD3-PWWP1",
    "method": "[\"X-RAY DIFFRACTION\"]",
    "resolution_angstrom": 2.8,
    "primary_classification": "APO",
    "observed_PWWP": 1,
    "review_required": 0,
    "review_reasons": "[]",
    "release_date": "2019-06-26T00:00:00.000+00:00",
    "source_url": "https://www.rcsb.org/structure/6G3P",
    "coordinate_url": "https://files.rcsb.org/download/6G3P.cif",
    "original_cif_sha256": "ccd521e797a74fb99b19d2058837b9b848f522886e1772907e6b742dff24e0ad",
    "classification_status": "v1 classification retained; independent coverage/contact evidence and sampled scientific audit are separate layers"
  },
  "chains": [
    {
      "auth_asym_ids_observed": "[\"A\"]",
      "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
      "chain_id": "PDB:6G3P:CHAIN:A:UP:Q9BZ95",
      "core_definition_source": "UniProtKB reviewed feature",
      "domain_id": "UP:Q9BZ95:PWWP1",
      "entity_id": "1",
      "gene": "NSD3",
      "isolated_PWWP_containing_construct_candidate": 1,
      "label_asym_id": "A",
      "mapped_construct_ranges": "[[247, 398]]",
      "native_core_end": 333,
      "native_core_start": 270,
      "observed_chain_residue_count": 124,
      "observed_core_residue_count": 64,
      "pdb_id": "6G3P",
      "pfam_entity_ranges": "[[26, 135]]",
      "protein_id": "UP:Q9BZ95",
      "source_entity_json": "Structures/NSD3__HUMAN__Q9BZ95/APO/6G3P/polymer_entities.json",
      "source_entity_json_sha256": "04ecbae3c0946736db969550694e316445d136820012d8579d795eb0aca7cc7b"
    },
    {
      "auth_asym_ids_observed": "[\"B\"]",
      "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
      "chain_id": "PDB:6G3P:CHAIN:B:UP:Q9BZ95",
      "core_definition_source": "UniProtKB reviewed feature",
      "domain_id": "UP:Q9BZ95:PWWP1",
      "entity_id": "1",
      "gene": "NSD3",
      "isolated_PWWP_containing_construct_candidate": 1,
      "label_asym_id": "B",
      "mapped_construct_ranges": "[[247, 398]]",
      "native_core_end": 333,
      "native_core_start": 270,
      "observed_chain_residue_count": 128,
      "observed_core_residue_count": 64,
      "pdb_id": "6G3P",
      "pfam_entity_ranges": "[[26, 135]]",
      "protein_id": "UP:Q9BZ95",
      "source_entity_json": "Structures/NSD3__HUMAN__Q9BZ95/APO/6G3P/polymer_entities.json",
      "source_entity_json_sha256": "04ecbae3c0946736db969550694e316445d136820012d8579d795eb0aca7cc7b"
    },
    {
      "auth_asym_ids_observed": "[\"C\"]",
      "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
      "chain_id": "PDB:6G3P:CHAIN:C:UP:Q9BZ95",
      "core_definition_source": "UniProtKB reviewed feature",
      "domain_id": "UP:Q9BZ95:PWWP1",
      "entity_id": "1",
      "gene": "NSD3",
      "isolated_PWWP_containing_construct_candidate": 1,
      "label_asym_id": "C",
      "mapped_construct_ranges": "[[247, 398]]",
      "native_core_end": 333,
      "native_core_start": 270,
      "observed_chain_residue_count": 111,
      "observed_core_residue_count": 64,
      "pdb_id": "6G3P",
      "pfam_entity_ranges": "[[26, 135]]",
      "protein_id": "UP:Q9BZ95",
      "source_entity_json": "Structures/NSD3__HUMAN__Q9BZ95/APO/6G3P/polymer_entities.json",
      "source_entity_json_sha256": "04ecbae3c0946736db969550694e316445d136820012d8579d795eb0aca7cc7b"
    },
    {
      "auth_asym_ids_observed": "[\"D\"]",
      "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
      "chain_id": "PDB:6G3P:CHAIN:D:UP:Q9BZ95",
      "core_definition_source": "UniProtKB reviewed feature",
      "domain_id": "UP:Q9BZ95:PWWP1",
      "entity_id": "1",
      "gene": "NSD3",
      "isolated_PWWP_containing_construct_candidate": 1,
      "label_asym_id": "D",
      "mapped_construct_ranges": "[[247, 398]]",
      "native_core_end": 333,
      "native_core_start": 270,
      "observed_chain_residue_count": 110,
      "observed_core_residue_count": 64,
      "pdb_id": "6G3P",
      "pfam_entity_ranges": "[[26, 135]]",
      "protein_id": "UP:Q9BZ95",
      "source_entity_json": "Structures/NSD3__HUMAN__Q9BZ95/APO/6G3P/polymer_entities.json",
      "source_entity_json_sha256": "04ecbae3c0946736db969550694e316445d136820012d8579d795eb0aca7cc7b"
    }
  ],
  "chain": {
    "auth_asym_ids_observed": "[\"B\"]",
    "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
    "chain_id": "PDB:6G3P:CHAIN:B:UP:Q9BZ95",
    "core_definition_source": "UniProtKB reviewed feature",
    "domain_id": "UP:Q9BZ95:PWWP1",
    "entity_id": "1",
    "gene": "NSD3",
    "isolated_PWWP_containing_construct_candidate": 1,
    "label_asym_id": "B",
    "mapped_construct_ranges": "[[247, 398]]",
    "native_core_end": 333,
    "native_core_start": 270,
    "observed_chain_residue_count": 128,
    "observed_core_residue_count": 64,
    "pdb_id": "6G3P",
    "pfam_entity_ranges": "[[26, 135]]",
    "protein_id": "UP:Q9BZ95",
    "source_entity_json": "Structures/NSD3__HUMAN__Q9BZ95/APO/6G3P/polymer_entities.json",
    "source_entity_json_sha256": "04ecbae3c0946736db969550694e316445d136820012d8579d795eb0aca7cc7b"
  },
  "sites": [],
  "site": null,
  "quality": null,
  "contacts": [],
  "comparison": {
    "comparison_id": "6G3P:B:UP:Q9BZ95:PWWP1",
    "pdb_id": "6G3P",
    "protein_id": "UP:Q9BZ95",
    "gene": "NSD3",
    "taxonomy_id": "9606",
    "domain_id": "UP:Q9BZ95:PWWP1",
    "label_asym_id": "B",
    "auth_asym_ids": "[\"B\"]",
    "first_model": "1",
    "domain_start": 270,
    "domain_end": 333,
    "annotation_core_length": 64,
    "n_observed_CA": 64,
    "core_CA_coverage": 1.0,
    "v1_observed_any_atom_residues": 64,
    "CA_minus_v1_any_atom": 0,
    "n_common_AF_CA": 64,
    "core_observed_substitutions": 0,
    "substitutions": "[]",
    "duplicate_canonical_positions": "[]",
    "experimental_method": "X-RAY DIFFRACTION",
    "resolution_angstrom": 2.8,
    "primary_classification": "APO",
    "classification_review_required": 0,
    "source_cif": "Structures/NSD3__HUMAN__Q9BZ95/APO/6G3P/original.cif",
    "source_sha256": "ccd521e797a74fb99b19d2058837b9b848f522886e1772907e6b742dff24e0ad",
    "mapping_sha256": "c90c45d1c74515e47c408cad642872483dd9ad18c634dbada7dee6d367083e5f",
    "comparison_status": "eligible",
    "AF_model_record_id": "AF-Q9BZ95-F1:v6",
    "rmsd_all_common_CA": 0.747916,
    "n_AF_CA_ge70": 63,
    "rmsd_AF_ge70_CA": 0.731572,
    "AF_core_mean_plddt": 89.4437
  },
  "assays": [],
  "local_coordinates": true,
  "coordinate_url": "/coordinates/phase6c1/6G3P.cif",
  "interpretation": "Heavy-atom distances use the first deposited model and asymmetric unit, occupancy >0 and retained alternate locations. No symmetry expansion or affinity inference.",
  "quality_scope": "Detailed atom completeness only for the three packaged original-coordinate files; quality uses observed atom-name union across positive-occupancy alternate conformers, with per-alt differences retained. Missing entire residues are separate. Nonstandard amino-acid templates are unassessed. No density reinterpretation, receptor repair, docking or MD.",
  "analysis_id": "PWWP_POCKET_QUALITY_1.0.0",
  "source_conflict": null
}