{
  "science_site": null,
  "structure": {
    "pdb_id": "3EAE",
    "title": "PWWP domain of human hepatoma-derived growth factor 2 (HDGF2)",
    "method": "[\"X-RAY DIFFRACTION\"]",
    "resolution_angstrom": 2.24,
    "primary_classification": "APO",
    "observed_PWWP": 1,
    "review_required": 0,
    "review_reasons": "[]",
    "release_date": "2008-09-16T00:00:00.000+00:00",
    "source_url": "https://www.rcsb.org/structure/3EAE",
    "coordinate_url": "https://files.rcsb.org/download/3EAE.cif",
    "original_cif_sha256": "3073a9f7f57ac2d4bb5511c8c6a9c6aed8f18f89d16ebac7d54e6984f02aace1",
    "classification_status": "v1 classification retained; independent coverage/contact evidence and sampled scientific audit are separate layers"
  },
  "chains": [
    {
      "auth_asym_ids_observed": "[\"A\"]",
      "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
      "chain_id": "PDB:3EAE:CHAIN:A:UP:Q7Z4V5",
      "core_definition_source": "UniProtKB reviewed feature",
      "domain_id": "UP:Q7Z4V5:PWWP1",
      "entity_id": "1",
      "gene": "HDGFL2",
      "isolated_PWWP_containing_construct_candidate": 1,
      "label_asym_id": "A",
      "mapped_construct_ranges": "[[1, 93]]",
      "native_core_end": 64,
      "native_core_start": 7,
      "observed_chain_residue_count": 92,
      "observed_core_residue_count": 58,
      "pdb_id": "3EAE",
      "pfam_entity_ranges": "[[8, 89]]",
      "protein_id": "UP:Q7Z4V5",
      "source_entity_json": "Structures/HDGFL2__HUMAN__Q7Z4V5/APO/3EAE/polymer_entities.json",
      "source_entity_json_sha256": "662895729265f3834d3dc9b21499da91f6300c566fa827039117927efd0677e6"
    },
    {
      "auth_asym_ids_observed": "[\"B\"]",
      "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
      "chain_id": "PDB:3EAE:CHAIN:B:UP:Q7Z4V5",
      "core_definition_source": "UniProtKB reviewed feature",
      "domain_id": "UP:Q7Z4V5:PWWP1",
      "entity_id": "1",
      "gene": "HDGFL2",
      "isolated_PWWP_containing_construct_candidate": 1,
      "label_asym_id": "B",
      "mapped_construct_ranges": "[[1, 93]]",
      "native_core_end": 64,
      "native_core_start": 7,
      "observed_chain_residue_count": 75,
      "observed_core_residue_count": 47,
      "pdb_id": "3EAE",
      "pfam_entity_ranges": "[[8, 89]]",
      "protein_id": "UP:Q7Z4V5",
      "source_entity_json": "Structures/HDGFL2__HUMAN__Q7Z4V5/APO/3EAE/polymer_entities.json",
      "source_entity_json_sha256": "662895729265f3834d3dc9b21499da91f6300c566fa827039117927efd0677e6"
    }
  ],
  "chain": {
    "auth_asym_ids_observed": "[\"B\"]",
    "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
    "chain_id": "PDB:3EAE:CHAIN:B:UP:Q7Z4V5",
    "core_definition_source": "UniProtKB reviewed feature",
    "domain_id": "UP:Q7Z4V5:PWWP1",
    "entity_id": "1",
    "gene": "HDGFL2",
    "isolated_PWWP_containing_construct_candidate": 1,
    "label_asym_id": "B",
    "mapped_construct_ranges": "[[1, 93]]",
    "native_core_end": 64,
    "native_core_start": 7,
    "observed_chain_residue_count": 75,
    "observed_core_residue_count": 47,
    "pdb_id": "3EAE",
    "pfam_entity_ranges": "[[8, 89]]",
    "protein_id": "UP:Q7Z4V5",
    "source_entity_json": "Structures/HDGFL2__HUMAN__Q7Z4V5/APO/3EAE/polymer_entities.json",
    "source_entity_json_sha256": "662895729265f3834d3dc9b21499da91f6300c566fa827039117927efd0677e6"
  },
  "sites": [],
  "site": null,
  "quality": null,
  "contacts": [],
  "comparison": {
    "comparison_id": "3EAE:B:UP:Q7Z4V5:PWWP1",
    "pdb_id": "3EAE",
    "protein_id": "UP:Q7Z4V5",
    "gene": "HDGFL2",
    "taxonomy_id": "9606",
    "domain_id": "UP:Q7Z4V5:PWWP1",
    "label_asym_id": "B",
    "auth_asym_ids": "[\"B\"]",
    "first_model": "1",
    "domain_start": 7,
    "domain_end": 64,
    "annotation_core_length": 58,
    "n_observed_CA": 47,
    "core_CA_coverage": 0.810345,
    "v1_observed_any_atom_residues": 47,
    "CA_minus_v1_any_atom": 0,
    "n_common_AF_CA": 47,
    "core_observed_substitutions": 0,
    "substitutions": "[]",
    "duplicate_canonical_positions": "[]",
    "experimental_method": "X-RAY DIFFRACTION",
    "resolution_angstrom": 2.24,
    "primary_classification": "APO",
    "classification_review_required": 0,
    "source_cif": "Structures/HDGFL2__HUMAN__Q7Z4V5/APO/3EAE/original.cif",
    "source_sha256": "3073a9f7f57ac2d4bb5511c8c6a9c6aed8f18f89d16ebac7d54e6984f02aace1",
    "mapping_sha256": "75106960304aa764cb9f1e122aba4ddba85556ce3ed87a42a817870c9a8f8897",
    "comparison_status": "eligible",
    "AF_model_record_id": "AF-Q7Z4V5-F1:v6",
    "rmsd_all_common_CA": 0.339038,
    "n_AF_CA_ge70": 47,
    "rmsd_AF_ge70_CA": 0.339038,
    "AF_core_mean_plddt": 94.0557
  },
  "assays": [],
  "local_coordinates": true,
  "coordinate_url": "/coordinates/phase6c1/3EAE.cif",
  "interpretation": "Heavy-atom distances use the first deposited model and asymmetric unit, occupancy >0 and retained alternate locations. No symmetry expansion or affinity inference.",
  "quality_scope": "Detailed atom completeness only for the three packaged original-coordinate files; quality uses observed atom-name union across positive-occupancy alternate conformers, with per-alt differences retained. Missing entire residues are separate. Nonstandard amino-acid templates are unassessed. No density reinterpretation, receptor repair, docking or MD.",
  "analysis_id": "PWWP_POCKET_QUALITY_1.0.0",
  "source_conflict": null
}