{
  "science_site": null,
  "structure": {
    "pdb_id": "7E29",
    "title": "Crystal Structure of Saccharomyces cerevisiae Ioc4 PWWP domain fused with MBP",
    "method": "[\"X-RAY DIFFRACTION\"]",
    "resolution_angstrom": 2.303,
    "primary_classification": "APO",
    "observed_PWWP": 1,
    "review_required": 0,
    "review_reasons": "[]",
    "release_date": "2022-02-09T00:00:00.000+00:00",
    "source_url": "https://www.rcsb.org/structure/7E29",
    "coordinate_url": "https://files.rcsb.org/download/7E29.cif",
    "original_cif_sha256": "be170b7f5d76f97ab8c857b3137e15972e49648f512e2fa59f67906a6e98f617",
    "classification_status": "v1 classification retained; independent coverage/contact evidence and sampled scientific audit are separate layers"
  },
  "chains": [
    {
      "auth_asym_ids_observed": "[\"A\"]",
      "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
      "chain_id": "PDB:7E29:CHAIN:A:UP:Q04213",
      "core_definition_source": "InterPro/Pfam PF00855",
      "domain_id": "UP:Q04213:PWWP1",
      "entity_id": "1",
      "gene": "IOC4",
      "isolated_PWWP_containing_construct_candidate": 0,
      "label_asym_id": "A",
      "mapped_construct_ranges": "[[1, 178]]",
      "native_core_end": 160,
      "native_core_start": 10,
      "observed_chain_residue_count": 496,
      "observed_core_residue_count": 101,
      "pdb_id": "7E29",
      "pfam_entity_ranges": "[[382, 536]]",
      "protein_id": "UP:Q04213",
      "source_entity_json": "Structures/IOC4__TAX559292__Q04213/APO/7E29/polymer_entities.json",
      "source_entity_json_sha256": "fb2be6ee86ef4532fa13fe44e644565ed9e9624ce1c02120d5ff75f01a30c5f3"
    }
  ],
  "chain": {
    "auth_asym_ids_observed": "[\"A\"]",
    "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
    "chain_id": "PDB:7E29:CHAIN:A:UP:Q04213",
    "core_definition_source": "InterPro/Pfam PF00855",
    "domain_id": "UP:Q04213:PWWP1",
    "entity_id": "1",
    "gene": "IOC4",
    "isolated_PWWP_containing_construct_candidate": 0,
    "label_asym_id": "A",
    "mapped_construct_ranges": "[[1, 178]]",
    "native_core_end": 160,
    "native_core_start": 10,
    "observed_chain_residue_count": 496,
    "observed_core_residue_count": 101,
    "pdb_id": "7E29",
    "pfam_entity_ranges": "[[382, 536]]",
    "protein_id": "UP:Q04213",
    "source_entity_json": "Structures/IOC4__TAX559292__Q04213/APO/7E29/polymer_entities.json",
    "source_entity_json_sha256": "fb2be6ee86ef4532fa13fe44e644565ed9e9624ce1c02120d5ff75f01a30c5f3"
  },
  "sites": [],
  "site": null,
  "quality": null,
  "contacts": [],
  "comparison": {
    "comparison_id": "7E29:A:UP:Q04213:PWWP1",
    "pdb_id": "7E29",
    "protein_id": "UP:Q04213",
    "gene": "IOC4",
    "taxonomy_id": "559292",
    "domain_id": "UP:Q04213:PWWP1",
    "label_asym_id": "A",
    "auth_asym_ids": "[\"A\"]",
    "first_model": "1",
    "domain_start": 10,
    "domain_end": 160,
    "annotation_core_length": 151,
    "n_observed_CA": 101,
    "core_CA_coverage": 0.668874,
    "v1_observed_any_atom_residues": 101,
    "CA_minus_v1_any_atom": 0,
    "n_common_AF_CA": 101,
    "core_observed_substitutions": 0,
    "substitutions": "[]",
    "duplicate_canonical_positions": "[]",
    "experimental_method": "X-RAY DIFFRACTION",
    "resolution_angstrom": 2.303,
    "primary_classification": "APO",
    "classification_review_required": 0,
    "source_cif": "Structures/IOC4__TAX559292__Q04213/APO/7E29/original.cif",
    "source_sha256": "be170b7f5d76f97ab8c857b3137e15972e49648f512e2fa59f67906a6e98f617",
    "mapping_sha256": "39c763e07ae9df65ad61d0499ba6ea568fa11b29eec74f92f0c7f00fea50ca35",
    "comparison_status": "insufficient_common_core_CA",
    "AF_model_record_id": "AF-Q04213-F1:v6",
    "rmsd_all_common_CA": null,
    "n_AF_CA_ge70": 0,
    "rmsd_AF_ge70_CA": null,
    "AF_core_mean_plddt": 90.688
  },
  "assays": [],
  "local_coordinates": true,
  "coordinate_url": "/coordinates/phase6c1/7E29.cif",
  "interpretation": "Heavy-atom distances use the first deposited model and asymmetric unit, occupancy >0 and retained alternate locations. No symmetry expansion or affinity inference.",
  "quality_scope": "Detailed atom completeness only for the three packaged original-coordinate files; quality uses observed atom-name union across positive-occupancy alternate conformers, with per-alt differences retained. Missing entire residues are separate. Nonstandard amino-acid templates are unassessed. No density reinterpretation, receptor repair, docking or MD.",
  "analysis_id": "PWWP_POCKET_QUALITY_1.0.0",
  "source_conflict": null
}