{
  "science_site": null,
  "structure": {
    "pdb_id": "7V8N",
    "title": "Crystal structure of the PWWP-ARID domain of ARID4A",
    "method": "[\"X-RAY DIFFRACTION\"]",
    "resolution_angstrom": 2.05,
    "primary_classification": "APO",
    "observed_PWWP": 1,
    "review_required": 0,
    "review_reasons": "[]",
    "release_date": "2022-08-31T00:00:00.000+00:00",
    "source_url": "https://www.rcsb.org/structure/7V8N",
    "coordinate_url": "https://files.rcsb.org/download/7V8N.cif",
    "original_cif_sha256": "d33ca5e9bcd7721563170a9c48be248295c3778879e47ca008908a349a8ef1ef",
    "classification_status": "v1 classification retained; independent coverage/contact evidence and sampled scientific audit are separate layers"
  },
  "chains": [
    {
      "auth_asym_ids_observed": "[\"A\"]",
      "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
      "chain_id": "PDB:7V8N:CHAIN:A:UP:P29374",
      "core_definition_source": "pfam via InterPro API",
      "domain_id": "UP:P29374:PWWP1",
      "entity_id": "1",
      "gene": "ARID4A",
      "isolated_PWWP_containing_construct_candidate": 0,
      "label_asym_id": "A",
      "mapped_construct_ranges": "[[169, 417]]",
      "native_core_end": 262,
      "native_core_start": 170,
      "observed_chain_residue_count": 220,
      "observed_core_residue_count": 93,
      "pdb_id": "7V8N",
      "pfam_entity_ranges": "[[6, 98]]",
      "protein_id": "UP:P29374",
      "source_entity_json": "Structures/ARID4A__HUMAN__P29374/APO/7V8N/polymer_entities.json",
      "source_entity_json_sha256": "42305fc64c9b95651ff69c54e1ceeef4401872a9c62f4d288a79723b9c112ca2"
    },
    {
      "auth_asym_ids_observed": "[\"B\"]",
      "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
      "chain_id": "PDB:7V8N:CHAIN:B:UP:P29374",
      "core_definition_source": "pfam via InterPro API",
      "domain_id": "UP:P29374:PWWP1",
      "entity_id": "1",
      "gene": "ARID4A",
      "isolated_PWWP_containing_construct_candidate": 0,
      "label_asym_id": "B",
      "mapped_construct_ranges": "[[169, 417]]",
      "native_core_end": 262,
      "native_core_start": 170,
      "observed_chain_residue_count": 208,
      "observed_core_residue_count": 85,
      "pdb_id": "7V8N",
      "pfam_entity_ranges": "[[6, 98]]",
      "protein_id": "UP:P29374",
      "source_entity_json": "Structures/ARID4A__HUMAN__P29374/APO/7V8N/polymer_entities.json",
      "source_entity_json_sha256": "42305fc64c9b95651ff69c54e1ceeef4401872a9c62f4d288a79723b9c112ca2"
    }
  ],
  "chain": {
    "auth_asym_ids_observed": "[\"A\"]",
    "broader_scope_basis": "source Pfam feature intersecting native core; entire chain reported separately",
    "chain_id": "PDB:7V8N:CHAIN:A:UP:P29374",
    "core_definition_source": "pfam via InterPro API",
    "domain_id": "UP:P29374:PWWP1",
    "entity_id": "1",
    "gene": "ARID4A",
    "isolated_PWWP_containing_construct_candidate": 0,
    "label_asym_id": "A",
    "mapped_construct_ranges": "[[169, 417]]",
    "native_core_end": 262,
    "native_core_start": 170,
    "observed_chain_residue_count": 220,
    "observed_core_residue_count": 93,
    "pdb_id": "7V8N",
    "pfam_entity_ranges": "[[6, 98]]",
    "protein_id": "UP:P29374",
    "source_entity_json": "Structures/ARID4A__HUMAN__P29374/APO/7V8N/polymer_entities.json",
    "source_entity_json_sha256": "42305fc64c9b95651ff69c54e1ceeef4401872a9c62f4d288a79723b9c112ca2"
  },
  "sites": [],
  "site": null,
  "quality": null,
  "contacts": [],
  "comparison": {
    "comparison_id": "7V8N:A:UP:P29374:PWWP1",
    "pdb_id": "7V8N",
    "protein_id": "UP:P29374",
    "gene": "ARID4A",
    "taxonomy_id": "9606",
    "domain_id": "UP:P29374:PWWP1",
    "label_asym_id": "A",
    "auth_asym_ids": "[\"A\"]",
    "first_model": "1",
    "domain_start": 170,
    "domain_end": 262,
    "annotation_core_length": 93,
    "n_observed_CA": 93,
    "core_CA_coverage": 1.0,
    "v1_observed_any_atom_residues": 93,
    "CA_minus_v1_any_atom": 0,
    "n_common_AF_CA": 93,
    "core_observed_substitutions": 0,
    "substitutions": "[]",
    "duplicate_canonical_positions": "[]",
    "experimental_method": "X-RAY DIFFRACTION",
    "resolution_angstrom": 2.05,
    "primary_classification": "APO",
    "classification_review_required": 0,
    "source_cif": "Structures/ARID4A__HUMAN__P29374/APO/7V8N/original.cif",
    "source_sha256": "d33ca5e9bcd7721563170a9c48be248295c3778879e47ca008908a349a8ef1ef",
    "mapping_sha256": "7ce57656980b1aa6a0047f11ac802f61c7169ef9d12b9399ba94f1b23a00fc9b",
    "comparison_status": "eligible",
    "AF_model_record_id": "AF-P29374-F1:v6",
    "rmsd_all_common_CA": 1.819829,
    "n_AF_CA_ge70": 91,
    "rmsd_AF_ge70_CA": 1.450526,
    "AF_core_mean_plddt": 86.6214
  },
  "assays": [],
  "local_coordinates": true,
  "coordinate_url": "/coordinates/phase6c1/7V8N.cif",
  "interpretation": "Heavy-atom distances use the first deposited model and asymmetric unit, occupancy >0 and retained alternate locations. No symmetry expansion or affinity inference.",
  "quality_scope": "Detailed atom completeness only for the three packaged original-coordinate files; quality uses observed atom-name union across positive-occupancy alternate conformers, with per-alt differences retained. Missing entire residues are separate. Nonstandard amino-acid templates are unassessed. No density reinterpretation, receptor repair, docking or MD.",
  "analysis_id": "PWWP_POCKET_QUALITY_1.0.0",
  "source_conflict": null
}