[
  {
    "query": "PWWP inhibitors NSD2 NSD3 chemical probes UNC6934 UNC7145 BI-9321",
    "source": "web search for primary sources",
    "retrieval_date": "2026-10-26",
    "inclusion_rule": "explicit PWWP-domain assay or source-supported cellular modulator; identity/source context checked before curation"
  },
  {
    "query": "PWWP HDGF LEDGF small molecule inhibitor direct binding MR927",
    "source": "web search for primary sources",
    "retrieval_date": "2026-10-26",
    "inclusion_rule": "explicit PWWP-domain assay or source-supported cellular modulator; identity/source context checked before curation"
  },
  {
    "query": "PWWP NSD2 inhibitor 2024 2025 compound Collie",
    "source": "web search for primary sources",
    "retrieval_date": "2026-10-26",
    "inclusion_rule": "explicit PWWP-domain assay or source-supported cellular modulator; identity/source context checked before curation"
  },
  {
    "query": "PWWP NSD3 inhibitors 2024 2025 compound degrader",
    "source": "web search for primary sources",
    "retrieval_date": "2026-10-26",
    "inclusion_rule": "explicit PWWP-domain assay or source-supported cellular modulator; identity/source context checked before curation"
  },
  {
    "query": "HDGFL2 PWWP fragment Kd rational fragment-based 2024",
    "source": "web search for primary sources",
    "retrieval_date": "2026-10-26",
    "inclusion_rule": "explicit PWWP-domain assay or source-supported cellular modulator; identity/source context checked before curation"
  },
  {
    "query": "LEDGF PWWP inhibitor compound 2026",
    "source": "web search for primary sources",
    "retrieval_date": "2026-10-26",
    "inclusion_rule": "explicit PWWP-domain assay or source-supported cellular modulator; identity/source context checked before curation"
  },
  {
    "query": "site:pmc.ncbi.nlm.nih.gov NSD2 UNC8153",
    "source": "web search for primary sources",
    "retrieval_date": "2026-10-26",
    "inclusion_rule": "explicit PWWP-domain assay or source-supported cellular modulator; identity/source context checked before curation"
  },
  {
    "query": "NSD3 MS9715 Kd",
    "source": "web search for primary sources",
    "retrieval_date": "2026-10-26",
    "inclusion_rule": "explicit PWWP-domain assay or source-supported cellular modulator; identity/source context checked before curation"
  },
  {
    "query": "1873-3468.14981 PSIP1",
    "source": "web search for primary sources",
    "retrieval_date": "2026-10-26",
    "inclusion_rule": "explicit PWWP-domain assay or source-supported cellular modulator; identity/source context checked before curation"
  },
  {
    "query": "NSD2 HS13 IC50",
    "source": "web search for primary sources",
    "retrieval_date": "2026-10-26",
    "inclusion_rule": "explicit PWWP-domain assay or source-supported cellular modulator; identity/source context checked before curation"
  },
  {
    "query": "Identification of Novel Potent NSD2-PWWP1 Ligands pdf",
    "source": "web search for primary sources",
    "retrieval_date": "2026-10-26",
    "inclusion_rule": "explicit PWWP-domain assay or source-supported cellular modulator; identity/source context checked before curation"
  },
  {
    "query": "Recruitment of FBXO22 UNC8732 Kd",
    "source": "web search for primary sources",
    "retrieval_date": "2026-10-26",
    "inclusion_rule": "explicit PWWP-domain assay or source-supported cellular modulator; identity/source context checked before curation"
  },
  {
    "query": "Fragment-based discovery BI-9466 32",
    "source": "web search for primary sources",
    "retrieval_date": "2026-10-26",
    "inclusion_rule": "explicit PWWP-domain assay or source-supported cellular modulator; identity/source context checked before curation"
  },
  {
    "query": "PWWP ChEMBL Carlino",
    "source": "web search for primary sources",
    "retrieval_date": "2026-10-26",
    "inclusion_rule": "explicit PWWP-domain assay or source-supported cellular modulator; identity/source context checked before curation"
  },
  {
    "query": "ChEMBL assay description__icontains=PWWP; limit1000; first-page total110 next=null",
    "source": "ChEMBL API",
    "url": "https://www.ebi.ac.uk/chembl/api/data/assay.json?description__icontains=PWWP&limit=1000",
    "retrieval_date": "2026-10-26",
    "records_found": 110,
    "coverage_note": "Bounded keyword discovery across all ChEMBL targets plus exact component-accession mapping for NSD2/NSD3/PSIP1/HDGFL2. Contains indirect PWWP2B expression assays and non-PWWP counter-screen targets; all require review."
  },
  {
    "query": "\"MR927\" PWWP",
    "source": "web primary-source search",
    "retrieval_date": "2026-10-26",
    "purpose": "Final source audit and named-candidate verification"
  },
  {
    "query": "\"MR927\" inhibitor NSD2",
    "source": "web primary-source search",
    "retrieval_date": "2026-10-26",
    "purpose": "Final source audit and named-candidate verification"
  },
  {
    "query": "\"1873-3468.14981\" BPP ITC",
    "source": "web primary-source search",
    "retrieval_date": "2026-10-26",
    "purpose": "Final source audit and named-candidate verification"
  },
  {
    "query": "\"BPP\" \"PWWP\" \"14\" \"NMR\"",
    "source": "web primary-source search",
    "retrieval_date": "2026-10-26",
    "purpose": "Final source audit and named-candidate verification"
  },
  {
    "query": "\"HS13\" \"PWWP\" \"21.62\"",
    "source": "web primary-source search",
    "retrieval_date": "2026-10-26",
    "purpose": "Final source audit and named-candidate verification"
  },
  {
    "query": "site:febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14981 \"14\" \"27\"",
    "source": "web primary-source search",
    "retrieval_date": "2026-10-26",
    "purpose": "Final source audit and named-candidate verification"
  },
  {
    "query": "site:febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14981 \"7 ±\" \"250\"",
    "source": "web primary-source search",
    "retrieval_date": "2026-10-26",
    "purpose": "Final source audit and named-candidate verification"
  },
  {
    "query": "\"1873-3468.14981\" \"Tris\" NMR",
    "source": "web primary-source search",
    "retrieval_date": "2026-10-26",
    "purpose": "Final source audit and named-candidate verification"
  }
]