{"assembly_context":"asymmetric_unit_multi_chain_possible","assessment_status":"calculated_observed_ligand_environment","broader_pfam_contacts_at_5A":2,"ccd_id":"Y6V","contacting_residues_missing_sidechain_atoms":0,"contacts":[{"annotation_core":true,"canonical_position":228,"distance_angstrom":5.4279,"label_seq_id":18,"ligand_alt":null,"ligand_atom":"C9","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":[],"missing_sidechain_atoms_union":[],"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"O","protein_auth_asym_id":"A","protein_auth_seq_id":"228","protein_chain":"A","protein_component":"SER","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"native_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":true,"canonical_position":229,"distance_angstrom":5.9589,"label_seq_id":19,"ligand_alt":null,"ligand_atom":"C9","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":[],"missing_sidechain_atoms_union":[],"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"C","protein_auth_asym_id":"A","protein_auth_seq_id":"229","protein_chain":"A","protein_component":"LYS","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"native_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":true,"canonical_position":230,"distance_angstrom":3.687,"label_seq_id":20,"ligand_alt":null,"ligand_atom":"C9","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":[],"missing_sidechain_atoms_union":[],"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"CG2","protein_auth_asym_id":"A","protein_auth_seq_id":"230","protein_chain":"A","protein_component":"VAL","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"native_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":true,"canonical_position":233,"distance_angstrom":3.2316,"label_seq_id":23,"ligand_alt":null,"ligand_atom":"O1","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":[],"missing_sidechain_atoms_union":[],"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"CZ","protein_auth_asym_id":"A","protein_auth_seq_id":"233","protein_chain":"A","protein_component":"TYR","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"native_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":true,"canonical_position":234,"distance_angstrom":4.8696,"label_seq_id":24,"ligand_alt":null,"ligand_atom":"C8","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":[],"missing_sidechain_atoms_union":[],"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"O","protein_auth_asym_id":"A","protein_auth_seq_id":"234","protein_chain":"A","protein_component":"PRO","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"native_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":true,"canonical_position":236,"distance_angstrom":3.5963,"label_seq_id":26,"ligand_alt":null,"ligand_atom":"C8","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":[],"missing_sidechain_atoms_union":[],"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"CE3","protein_auth_asym_id":"A","protein_auth_seq_id":"236","protein_chain":"A","protein_component":"TRP","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"native_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":true,"canonical_position":266,"distance_angstrom":3.3574,"label_seq_id":56,"ligand_alt":null,"ligand_atom":"O3","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":[],"missing_sidechain_atoms_union":[],"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"CB","protein_auth_asym_id":"A","protein_auth_seq_id":"266","protein_chain":"A","protein_component":"PHE","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"native_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":true,"canonical_position":267,"distance_angstrom":3.3424,"label_seq_id":57,"ligand_alt":null,"ligand_atom":"C15","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":[],"missing_sidechain_atoms_union":[],"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"O","protein_auth_asym_id":"A","protein_auth_seq_id":"267","protein_chain":"A","protein_component":"PHE","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"native_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":true,"canonical_position":268,"distance_angstrom":3.2053,"label_seq_id":58,"ligand_alt":null,"ligand_atom":"O2","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":[],"missing_sidechain_atoms_union":[],"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"CA","protein_auth_asym_id":"A","protein_auth_seq_id":"268","protein_chain":"A","protein_component":"GLY","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"native_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":true,"canonical_position":269,"distance_angstrom":3.3252,"label_seq_id":59,"ligand_alt":null,"ligand_atom":"O2","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":[],"missing_sidechain_atoms_union":[],"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"N","protein_auth_asym_id":"A","protein_auth_seq_id":"269","protein_chain":"A","protein_component":"ASP","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"native_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":true,"canonical_position":270,"distance_angstrom":2.9387,"label_seq_id":60,"ligand_alt":null,"ligand_atom":"C14","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":[],"missing_sidechain_atoms_union":[],"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"O","protein_auth_asym_id":"A","protein_auth_seq_id":"270","protein_chain":"A","protein_component":"ALA","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"native_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":true,"canonical_position":271,"distance_angstrom":4.1671,"label_seq_id":61,"ligand_alt":null,"ligand_atom":"C15","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":[],"missing_sidechain_atoms_union":[],"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"CA","protein_auth_asym_id":"A","protein_auth_seq_id":"271","protein_chain":"A","protein_component":"PRO","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"native_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":true,"canonical_position":272,"distance_angstrom":3.3897,"label_seq_id":62,"ligand_alt":null,"ligand_atom":"C17","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":[],"missing_sidechain_atoms_union":[],"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"CG","protein_auth_asym_id":"A","protein_auth_seq_id":"272","protein_chain":"A","protein_component":"GLU","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"native_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":true,"canonical_position":273,"distance_angstrom":3.5671,"label_seq_id":63,"ligand_alt":null,"ligand_atom":"C6","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":[],"missing_sidechain_atoms_union":[],"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"O","protein_auth_asym_id":"A","protein_auth_seq_id":"273","protein_chain":"A","protein_component":"ARG","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"native_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":true,"canonical_position":274,"distance_angstrom":3.7595,"label_seq_id":64,"ligand_alt":null,"ligand_atom":"C5","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":[],"missing_sidechain_atoms_union":[],"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"CB","protein_auth_asym_id":"A","protein_auth_seq_id":"274","protein_chain":"A","protein_component":"ALA","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"native_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":true,"canonical_position":276,"distance_angstrom":5.765,"label_seq_id":66,"ligand_alt":null,"ligand_atom":"C4","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":[],"missing_sidechain_atoms_union":[],"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"CD1","protein_auth_asym_id":"A","protein_auth_seq_id":"276","protein_chain":"A","protein_component":"ILE","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"native_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":false,"canonical_position":318,"distance_angstrom":3.7833,"label_seq_id":108,"ligand_alt":null,"ligand_atom":"C12","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":null,"missing_sidechain_atoms_union":null,"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"CD1","protein_auth_asym_id":"A","protein_auth_seq_id":"318","protein_chain":"A","protein_component":"LEU","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"broader_pfam_outside_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"},{"annotation_core":false,"canonical_position":321,"distance_angstrom":2.9546,"label_seq_id":111,"ligand_alt":null,"ligand_atom":"N2","ligand_auth_asym_id":"A","ligand_component":"Y6V","ligand_label_asym_id":"I","ligand_occupancy":1.0,"missing_sidechain_atoms_conformer_consistent":null,"missing_sidechain_atoms_union":null,"model":1,"model_number":1,"pdb_id":"7MDN","protein_alt":null,"protein_atom":"OE1","protein_auth_asym_id":"A","protein_auth_seq_id":"321","protein_chain":"A","protein_component":"GLN","protein_insertion_code":null,"protein_occupancy":1.0,"quality_id":"7MDN:A:UP:O96028:PWWP1","region_type":"broader_pfam_outside_annotation_core","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a"}],"contacts_at_6A":18,"core_contacts_at_5A":13,"interpretation":"Observed source classified geometry, representative consistent alt state; distances do not imply favorable interaction or validated electron density.","ligand_alternate_conformers":[],"ligand_instance_id":"PDB:7MDN:LIG:I:Y6V:401:.","ligand_label_asym_id":"I","minimum_core_distance_angstrom":2.9387,"model":1,"pdb_id":"7MDN","protein_label_asym_id":"A","quality_id":"7MDN:A:UP:O96028:PWWP1","site_id":"PDB:7MDN:LIG:I:Y6V:401:.:SITE:UP:O96028:PWWP1:A","source_component_is_unmodified_parent":null,"source_coordinate_sha256":"411eea421108aa7f0e46d8c191904297040016aeabc0f48ef43d4a7503888c2a","source_role":"research_ligand","warnings":["multi_chain_environment_source_annotation"]}