{"assay_preparations":[{"chemical_id":"INCHIKEY:LKKNQJJSEMQTHQ-UHFFFAOYSA-N","entity_type":"small_molecule_preparation","exact_ccd_id":"A1D73","identity_note":"Complete deposited identity retained; no connectivity-only or name-only merge.","identity_status":"exact_single_CCD_identity","modeled_candidate_ccd_ids":"[]","modeled_candidate_chemical_ids":"[]","name":"BPP","preparation_id":"PREP:BPP","role":"assay_preparation","sequence_if_defined":null}],"assays_without_exact_contact_link":[{"DMSO_percent":null,"abstract_reported_endpoint":null,"abstract_reported_method":null,"abstract_reported_units":null,"abstract_reported_value":null,"assay_construct_end":null,"assay_construct_start":null,"assay_record_id":"PWWP:ASSAY:0013","assay_type":"Binding Kd; specific assay in Figure S2 not independently inspected","assay_value_transferred_to_modeled_stereoisomers":0,"audit_decision":"retain_with_explicit_endpoint_and_identity","baseline_assay_record":1,"buffer":null,"ccd_id":"A1D73","ccd_mapping_source":"Provenance/Literature/ligand_ccd_associations.json","chemical_id":"INCHIKEY:LKKNQJJSEMQTHQ-UHFFFAOYSA-N","chemical_identity_status":"exact_single_CCD_identity","component_context":null,"compound_name":"BPP","conditions":"{}","crystallographic_component_ids":null,"domain":"PWWP","domain_id":"UP:Q9Y3E1:PWWP1","endpoint_label_status":null,"evidence_class":"direct_binding_affinity","evidence_location":"Results: selectivity paragraph","evidence_url":"https://febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14981","gene":"HDGFL3","interpretation":"Numerical result verified in main text; precise supporting-assay details remain to be checked.","molecular_entity_type":"small_molecule_preparation","numeric_transcription_status":"matches_primary_report","numeric_value_inferred_from_structure":0,"pH":null,"pdb_id":null,"preparation_id":"PREP:BPP","protein_id":"UP:Q9Y3E1","qualitative_result":null,"reference_id":"PMID:39031937","remaining_uncertainty":"14 \u00b1 2 \u00b5M confirmed in primary Results; specific Figure S2 assay method remains unresolved.","replicates":null,"role":"experimentally_studied_fragment_ligand","source_component_url":null,"source_id":"S04","source_reported_uncertainty":"2","source_reported_units":"\u00b5M","source_reported_value":"14","source_verification_scope":"primary_publisher_selected_indexed_Results_and_Methods_passages; Figure S2 not independently retrieved","temperature_C":null,"uncertainty":2.0,"uncertainty_type":"fitting_error","uncertainty_uM":2.0,"unit_conversion":null,"units":"\u00b5M","value":14.0,"value_operator":"=","value_uM":14.0,"verification_level":"primary_full_text_sections_verified"}],"interpretation":"Exact links require chemical identity and the same native target/domain. An assay value remains attached to its measured construct and preparation. Unresolved and negative observations remain available without an exact-contact link.","protein":{"aliases":"[\"HDGF-2\",\"HDGF2\",\"HDGFRP3\",\"Hepatoma-derived growth factor 2\"]","attribution":"UniProt, CC BY 4.0","gene":"HDGFL3","length":203,"membership_tier":"annotation_supported","name":"Hepatoma-derived growth factor-related protein 3","organism":"Homo sapiens","protein_existence_caution":null,"protein_id":"UP:Q9Y3E1","sequence":"MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKTSEGT","sequence_sha256":"a1d99c34eb83960002f21423c5ba1db47d287c107a850d5dc14ccf73eb8da9bc","source_url":"https://www.uniprot.org/uniprotkb/Q9Y3E1","taxonomy_id":"9606","uniprot":"Q9Y3E1"},"structure_contact_assay_links":[]}