{"assay":{"DMSO_percent":null,"abstract_reported_endpoint":null,"abstract_reported_method":null,"abstract_reported_units":null,"abstract_reported_value":null,"assay_construct_end":null,"assay_construct_start":null,"assay_record_id":"PWWP:ASSAY:0036","assay_type":"X-ray structural association; no pharmacological activity assigned","assay_value_transferred_to_modeled_stereoisomers":0,"audit_decision":"separate_whole_peptide_preparation_from_M3L_monomer","baseline_assay_record":1,"buffer":null,"ccd_id":"M3L","ccd_mapping_source":null,"chemical_id":null,"chemical_identity_status":"defined_modified_peptide_sequence_not_monomer_identity","component_context":"nonstandard_polymer_monomer","compound_name":"H4K20me3 peptide / trimethyllysine monomer","conditions":"{}","crystallographic_component_ids":null,"domain":"PWWP","domain_id":"UP:Q7Z4V5:PWWP1","endpoint_label_status":null,"evidence_class":"structural_occupancy_association","evidence_location":"Table 2; RCSB polymer entity 2","evidence_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3119473/","gene":"HDGFL2","interpretation":"Chain H is an 11-residue H4K20me3 peptide AKRHR(M3L)VLRDN. M3L is a modified polymer monomer, not a free drug. The modeled subset must be distinguished from the full deposited peptide.","molecular_entity_type":"modified_histone_peptide","numeric_transcription_status":"not_a_quantitative_affinity_record","numeric_value_inferred_from_structure":0,"pH":null,"pdb_id":"3QBY","preparation_id":"PREP:H4K20me3_11mer","protein_id":"UP:Q7Z4V5","qualitative_result":null,"reference_id":"PMID:21720545","remaining_uncertainty":"M3L has a polymer residue identity. 3QBY structural occupancy coexists with very weak unfittable solution affinity in Table 1.","replicates":null,"role":"histone methyllysine surrogate/partially resolved peptide","source_component_url":"https://data.rcsb.org/rest/v1/core/polymer_entity/3QBY/2","source_id":"S07","source_reported_uncertainty":null,"source_reported_units":null,"source_reported_value":null,"source_verification_scope":"local_primary_full_text_XML; Tables 1-2, crystallization methods and ligand Results inspected","temperature_C":null,"uncertainty":null,"uncertainty_type":null,"uncertainty_uM":null,"unit_conversion":null,"units":null,"value":null,"value_operator":null,"value_uM":null,"verification_level":"primary_full_text_sections_verified"},"source_verification":null}
